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Xenon Pharmaceuticals Inc. (XENE) Fundamental Analysis & AI Grade 2026

XENE Nasdaq Pharmaceutical Preparations A1 CIK: 0001582313
Update Pending • Analysis: May 9, 2026 • SEC Data: 2026-03-31
Combined AI Grade
B
42% Confidence
N/A
B
42% Conf
Pending
Analysis scheduled

📊 XENE Key Takeaways

Revenue: $0.0
Net Margin: N/A
Free Cash Flow: $-89.0M
Current Ratio: 27.79x
Debt/Equity: 0.01x
EPS: $-1.17
AI Grade: B with 42% confidence
Xenon Pharmaceuticals Inc. (XENE) receives a B fundamental grade with 42% confidence from our AI analysis based on SEC 10-K filings. With revenue of $0, and return on equity (ROE) of -7.6%, Xenon Pharmaceuticals Inc. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete XENE stock analysis for 2026.

Is Xenon Pharmaceuticals Inc. (XENE) a Good Investment?

Claude

Xenon is a development-stage pharmaceutical company with a strong balance sheet ($546M cash, minimal debt) providing runway for R&D activities, but deteriorating net losses (-47.6% YoY) and complete revenue absence indicate substantial execution risk. Financial viability depends critically on clinical pipeline advancement and regulatory approval achievements.

Xenon Pharmaceuticals Inc. Key Strengths (XENE)

Claude
  • + Exceptional balance sheet with $546M cash and Debt/Equity of 0.01x
  • + Superior liquidity position (Current Ratio 27.79x) enabling extended development timeline
  • + Minimal financial distress risk with low absolute debt load ($11M long-term)

XENE Stock Risks: Xenon Pharmaceuticals Inc. Investment Risks

Claude
  • ! Zero revenue with undefined commercialization timeline
  • ! Deteriorating profitability trend (-47.6% YoY net loss decline)
  • ! Unsustainable cash burn rate of ~$89M annually dependent on pipeline success

Key Metrics to Watch

Claude
  • * Operating cash flow burn rate and remaining runway duration
  • * Clinical trial progression milestones and regulatory pathway status
  • * Revenue generation or partnership announcements indicating commercial traction

Xenon Pharmaceuticals Inc. (XENE) Financial Metrics & Key Ratios

Revenue
$0.0
Net Income
$-102.3M
EPS (Diluted)
$-1.17
Free Cash Flow
$-89.0M
Total Assets
$1.4B
Cash Position
$545.9M

💡 AI Analyst Insight

Strong liquidity with a 27.79x current ratio provides a solid financial cushion.

XENE Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin N/A
Net Margin N/A
ROE -7.6%
ROA -7.4%
FCF Margin N/A

XENE vs Healthcare Sector: How Xenon Pharmaceuticals Inc. Compares

How Xenon Pharmaceuticals Inc. compares to Healthcare sector averages

Net Margin
XENE 0.0%
vs
Sector Avg 12.0%
XENE Sector
ROE
XENE -7.6%
vs
Sector Avg 15.0%
XENE Sector
Current Ratio
XENE 27.8x
vs
Sector Avg 2.0x
XENE Sector
Debt/Equity
XENE 0.0x
vs
Sector Avg 0.6x
XENE Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Xenon Pharmaceuticals Inc. Stock Overvalued? XENE Valuation Analysis 2026

Based on fundamental analysis, Xenon Pharmaceuticals Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-7.6%
Sector avg: 15%
Net Profit Margin
N/A
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.01x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Xenon Pharmaceuticals Inc. Balance Sheet: XENE Debt, Cash & Liquidity

Current Ratio
27.79x
Quick Ratio
27.79x
Debt/Equity
0.01x
Debt/Assets
3.5%
Interest Coverage
-232.08x
Long-term Debt
$10.9M

XENE Revenue & Earnings Growth: 5-Year Financial Trend

XENE 5-year financial data: Year 2021: Revenue $32.2M, Net Income -$28.8M, EPS N/A. Year 2022: Revenue $32.2M, Net Income -$28.8M, EPS $-0.81. Year 2023: Revenue $18.4M, Net Income -$78.9M, EPS $-1.77. Year 2024: Revenue $9.4M, Net Income -$125.4M, EPS $-2.06. Year 2025: Revenue $7.5M, Net Income -$182.4M, EPS $-2.73.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Xenon Pharmaceuticals Inc.'s revenue has declined by 77% over the 5-year period, indicating business contraction. The most recent EPS of $-2.73 indicates the company is currently unprofitable.

XENE Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
N/A
Free cash flow / Revenue

XENE Quarterly Earnings & Performance

Quarterly financial performance data for Xenon Pharmaceuticals Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q1 2026 N/A -$65.0M $-0.83
Q3 2025 N/A -$47.9M $-0.81
Q2 2025 N/A -$47.9M $-0.75
Q1 2025 N/A -$47.9M $-0.62
Q3 2023 $132.0K -$19.7M $-0.57
Q2 2023 $536.0K -$19.7M $-0.55
Q1 2023 $8.8M -$19.7M $-0.35
Q3 2022 $132.0K -$15.4M $-0.36

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Xenon Pharmaceuticals Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$88.9M
Cash generated from operations
Capital Expenditures
$133.0K
Investment in assets
Dividends
None
No dividend program

XENE SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Xenon Pharmaceuticals Inc. (CIK: 0001582313)

📋 Recent SEC Filings

Date Form Document Action
Jun 8, 2026 4 xslF345X06/ownership.xml View →
Jun 8, 2026 4 xslF345X06/ownership.xml View →
Jun 3, 2026 4 xslF345X06/ownership.xml View →
Jun 3, 2026 4 xslF345X06/ownership.xml View →
Jun 3, 2026 4 xslF345X06/ownership.xml View →

Frequently Asked Questions about XENE

What is the AI rating for XENE?

Xenon Pharmaceuticals Inc. (XENE) has an AI grade of B with 42% confidence, based on fundamental analysis of SEC EDGAR filings.

What are XENE's key strengths?

Claude: Exceptional balance sheet with $546M cash and Debt/Equity of 0.01x. Superior liquidity position (Current Ratio 27.79x) enabling extended development timeline.

What are the risks of investing in XENE?

Claude: Zero revenue with undefined commercialization timeline. Deteriorating profitability trend (-47.6% YoY net loss decline).

What is XENE's revenue and growth?

Xenon Pharmaceuticals Inc. reported revenue of $0.0.

Does XENE pay dividends?

Xenon Pharmaceuticals Inc. does not currently pay dividends.

Where can I find XENE SEC filings?

Official SEC filings for Xenon Pharmaceuticals Inc. (CIK: 0001582313) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is XENE's EPS?

Xenon Pharmaceuticals Inc. has a diluted EPS of $-1.17.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined grade reflects both perspectives for balanced insights.

What is XENE's fundamental grade?

Based on our AI fundamental analysis in June 2026, Xenon Pharmaceuticals Inc. has a B grade with 42% confidence. Review the strengths and risks sections above for full context. This is not investment advice.

Is XENE stock overvalued or undervalued?

Valuation metrics for XENE: ROE of -7.6% (sector avg: 15%), net margin of N/A (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

What is XENE's AI grade for 2026?

Our dual AI analysis gives Xenon Pharmaceuticals Inc. a combined B grade for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is XENE's free cash flow?

Xenon Pharmaceuticals Inc.'s operating cash flow is $-88.9M, with capital expenditures of $133.0K.

How does XENE compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin N/A (avg: 12%), ROE -7.6% (avg: 15%), current ratio 27.79 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: May 9, 2026 | Data as of: 2026-03-31 | Powered by Claude AI