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Talphera, Inc.. (TLPH) Stock Fundamental Analysis & AI Rating 2026

TLPH Nasdaq Pharmaceutical Preparations DE CIK: 0001427925
Recently Updated • Analysis: May 15, 2026 • SEC Data: 2026-03-31
Combined AI Rating
SELL
72% Confidence
N/A
SELL
72% Conf
Pending
Analysis scheduled

📊 TLPH Key Takeaways

Revenue: $0.0
Net Margin: N/A
Free Cash Flow: $-3.4M
Current Ratio: 5.30x
Debt/Equity: 0.31x
EPS: $-0.10
AI Rating: SELL with 72% confidence
Talphera, Inc.. (TLPH) receives a SELL rating with 72% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $0, and return on equity (ROE) of -13.8%, Talphera, Inc.. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete TLPH stock analysis for 2026.

Is Talphera, Inc.. (TLPH) a Good Investment?

Claude

Talphera is a pre-revenue pharmaceutical company burning approximately $3.4M annually with only ~13 months of cash runway at current burn rates. While the balance sheet maintains moderate leverage (0.31x debt-to-equity) and strong liquidity ratios, the absence of revenue generation, deteriorating year-over-year EPS trends (-122.6%), and lack of capital expenditure create substantial execution risk requiring near-term clinical or commercial milestones.

Why Buy Talphera, Inc.. Stock? TLPH Key Strengths

Claude
  • + Strong liquidity position with current ratio of 5.30x and quick ratio of 5.01x
  • + Moderate debt-to-equity ratio of 0.31x provides financial flexibility
  • + Reasonable stockholders' equity base of $18.5M relative to asset size

TLPH Stock Risks: Talphera, Inc.. Investment Risks

Claude
  • ! Zero revenue with no clear path to near-term commercialization
  • ! Negative operating cash flow of -$3.4M annually creating urgent refinancing need
  • ! Limited cash runway of approximately 13 months at current burn rate
  • ! Deteriorating profitability with -122.6% year-over-year EPS decline
  • ! Absence of capital expenditure suggests limited product development investment for pharma sector

Key Metrics to Watch

Claude
  • * Cash balance and runway duration relative to quarterly burn rates
  • * Clinical trial progression and regulatory milestones
  • * Revenue recognition from any commercial or partnership activities

Talphera, Inc.. (TLPH) Financial Metrics & Key Ratios

Revenue
$0.0
Net Income
$-2.6M
EPS (Diluted)
$-0.10
Free Cash Flow
$-3.4M
Total Assets
$30.2M
Cash Position
$3.8M

💡 AI Analyst Insight

Strong liquidity with a 5.30x current ratio provides a solid financial cushion.

TLPH Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin N/A
Net Margin N/A
ROE -13.8%
ROA -8.5%
FCF Margin N/A

TLPH vs Healthcare Sector: How Talphera, Inc.. Compares

How Talphera, Inc.. compares to Healthcare sector averages

Net Margin
TLPH 0.0%
vs
Sector Avg 12.0%
TLPH Sector
ROE
TLPH -13.8%
vs
Sector Avg 15.0%
TLPH Sector
Current Ratio
TLPH 5.3x
vs
Sector Avg 2.0x
TLPH Sector
Debt/Equity
TLPH 0.3x
vs
Sector Avg 0.6x
TLPH Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Talphera, Inc.. Stock Overvalued? TLPH Valuation Analysis 2026

Based on fundamental analysis, Talphera, Inc.. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-13.8%
Sector avg: 15%
Net Profit Margin
N/A
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.31x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Talphera, Inc.. Balance Sheet: TLPH Debt, Cash & Liquidity

Current Ratio
5.30x
Quick Ratio
5.01x
Debt/Equity
0.31x
Debt/Assets
38.7%
Interest Coverage
N/A
Long-term Debt
$5.8M

TLPH Revenue & Earnings Growth: 5-Year Financial Trend

TLPH 5-year financial data: Year 2021: Revenue $5.4M, Net Income -$40.4M, EPS N/A. Year 2022: Revenue $2.8M, Net Income -$35.1M, EPS $-5.86. Year 2023: Revenue $651.0K, Net Income $47.8M, EPS $5.72. Year 2024: Revenue $651.0K, Net Income -$18.4M, EPS N/A. Year 2025: Revenue $28.0K, Net Income -$13.0M, EPS N/A.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Talphera, Inc..'s revenue has declined by 99% over the 5-year period, indicating business contraction. The most recent EPS of $5.72 reflects profitable operations.

TLPH Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
N/A
Free cash flow / Revenue

TLPH Quarterly Earnings & Performance

Quarterly financial performance data for Talphera, Inc.. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q1 2026 N/A -$2.6M N/A
Q3 2025 N/A -$2.6M N/A
Q2 2025 N/A -$2.6M N/A
Q1 2025 N/A -$2.6M $-0.10
Q3 2024 N/A -$1.4M N/A
Q2 2024 N/A -$3.8M N/A
Q3 2023 N/A -$1.4M $-0.08
Q2 2023 N/A -$4.4M $-0.40

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Talphera, Inc.. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$3.4M
Cash generated from operations
Dividends
None
No dividend program

TLPH SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Talphera, Inc.. (CIK: 0001427925)

📋 Recent SEC Filings

Date Form Document Action
May 13, 2026 10-Q acrx20260331_10q.htm View →
May 13, 2026 8-K acrx20260511_8k.htm View →
Apr 29, 2026 DEF 14A acrx20260422_def14a.htm View →
Apr 3, 2026 4 xslF345X06/form4-04032026_100412.xml View →
Apr 3, 2026 4 xslF345X06/form4-04032026_100414.xml View →

Frequently Asked Questions about TLPH

What is the AI rating for TLPH?

Talphera, Inc.. (TLPH) has an AI rating of SELL with 72% confidence, based on fundamental analysis of SEC EDGAR filings.

What are TLPH's key strengths?

Claude: Strong liquidity position with current ratio of 5.30x and quick ratio of 5.01x. Moderate debt-to-equity ratio of 0.31x provides financial flexibility.

What are the risks of investing in TLPH?

Claude: Zero revenue with no clear path to near-term commercialization. Negative operating cash flow of -$3.4M annually creating urgent refinancing need.

What is TLPH's revenue and growth?

Talphera, Inc.. reported revenue of $0.0.

Does TLPH pay dividends?

Talphera, Inc.. does not currently pay dividends.

Where can I find TLPH SEC filings?

Official SEC filings for Talphera, Inc.. (CIK: 0001427925) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is TLPH's EPS?

Talphera, Inc.. has a diluted EPS of $-0.10.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is TLPH a good stock to buy right now?

Based on our AI fundamental analysis in May 2026, Talphera, Inc.. has a SELL rating with 72% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is TLPH stock overvalued or undervalued?

Valuation metrics for TLPH: ROE of -13.8% (sector avg: 15%), net margin of N/A (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy TLPH stock in 2026?

Our dual AI analysis gives Talphera, Inc.. a combined SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is TLPH's free cash flow?

Talphera, Inc..'s operating cash flow is $-3.4M, with capital expenditures of $0.0.

How does TLPH compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin N/A (avg: 12%), ROE -13.8% (avg: 15%), current ratio 5.30 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: May 15, 2026 | Data as of: 2026-03-31 | Powered by Claude AI