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Stoke Therapeutics, Inc. (STOK) Stock Fundamental Analysis & AI Rating 2026

STOK Nasdaq Pharmaceutical Preparations DE CIK: 0001623526
Recently Updated • Analysis: Apr 16, 2026 • SEC Data: 2025-12-31
BUY
73% Conf
Pending
Analysis scheduled

📊 STOK Key Takeaways

Revenue: $184.4M
Net Margin: -3.7%
Free Cash Flow: $44.9M
Current Ratio: 5.28x
Debt/Equity: 0.00x
EPS: $-0.12
AI Rating: BUY with 73% confidence
Stoke Therapeutics, Inc. (STOK) receives a BUY rating with 73% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $184.4M, net profit margin of -3.7%, and return on equity (ROE) of -2.0%, Stoke Therapeutics, Inc. demonstrates strong fundamentals in the Healthcare sector. Below is our complete STOK stock analysis for 2026.

Is Stoke Therapeutics, Inc. (STOK) a Good Investment?

Claude

Stoke Therapeutics demonstrates compelling commercial traction with 404% revenue growth paired with positive free cash flow of $44.9M and zero debt, indicating successful product commercialization with clear profitability inflection approaching. The pristine balance sheet ($352.5M equity, $84.2M cash) and improving net loss trajectory despite operating losses suggest the company has substantial financial runway and is transitioning from growth phase to sustainable profitability.

Why Buy Stoke Therapeutics, Inc. Stock? STOK Key Strengths

Claude
  • + Exceptional 404% YoY revenue growth demonstrating successful product commercialization and market adoption
  • + Positive free cash flow of $44.9M with 24.4% FCF margin despite current operating losses, indicating underlying business health
  • + Fortress balance sheet with $352.5M stockholders' equity, zero long-term debt, and 5.28x current ratio providing substantial financial flexibility
  • + Improving profitability metrics with net loss stabilizing as revenue scales 400%+ YoY

STOK Stock Risks: Stoke Therapeutics, Inc. Investment Risks

Claude
  • ! Company remains operationally unprofitable with -$20.6M operating income and -11.2% operating margin despite revenue scale
  • ! Pharmaceutical sector inherent risks including regulatory approval, clinical outcome variability, and competitive pressures
  • ! High insider trading activity (21 Form 4 filings in 90 days) requires monitoring for potential sentiment shifts
  • ! Profitability inflection not yet demonstrated; continued losses could pressure cash burn if revenue growth decelerates

Key Metrics to Watch

Claude
  • * Operating margin progression toward breakeven and profitability as revenue scales
  • * Free cash flow sustainability and whether positive FCF persists through profitability transition
  • * Revenue growth rate trajectory and deceleration pattern to assess market saturation
  • * Operating income improvement and timeline to positive EBITDA as cost structure optimizes

Stoke Therapeutics, Inc. (STOK) Financial Metrics & Key Ratios

Revenue
$184.4M
Net Income
$-6.9M
EPS (Diluted)
$-0.12
Free Cash Flow
$44.9M
Total Assets
$418.4M
Cash Position
$84.2M

💡 AI Analyst Insight

The 24.4% free cash flow margin provides substantial flexibility for dividends, buybacks, and strategic investments. Strong liquidity with a 5.28x current ratio provides a solid financial cushion.

STOK Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin -11.2%
Net Margin -3.7%
ROE -2.0%
ROA -1.6%
FCF Margin 24.4%

STOK vs Healthcare Sector: How Stoke Therapeutics, Inc. Compares

How Stoke Therapeutics, Inc. compares to Healthcare sector averages

Net Margin
STOK -3.7%
vs
Sector Avg 12.0%
STOK Sector
ROE
STOK -2.0%
vs
Sector Avg 15.0%
STOK Sector
Current Ratio
STOK 5.3x
vs
Sector Avg 2.0x
STOK Sector
Debt/Equity
STOK 0.0x
vs
Sector Avg 0.6x
STOK Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Stoke Therapeutics, Inc. Stock Overvalued? STOK Valuation Analysis 2026

Based on fundamental analysis, Stoke Therapeutics, Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-2.0%
Sector avg: 15%
Net Profit Margin
-3.7%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Stoke Therapeutics, Inc. Balance Sheet: STOK Debt, Cash & Liquidity

Current Ratio
5.28x
Quick Ratio
5.28x
Debt/Equity
0.00x
Debt/Assets
15.8%
Interest Coverage
-2,287.78x
Long-term Debt
N/A

STOK Revenue & Earnings Growth: 5-Year Financial Trend

STOK 5-year financial data: Year 2022: Revenue $12.4M, Net Income -$85.8M, EPS $-2.34. Year 2023: Revenue $12.4M, Net Income -$101.1M, EPS $-2.60. Year 2024: Revenue $36.6M, Net Income -$104.7M, EPS $-2.38. Year 2025: Revenue $184.4M, Net Income -$89.0M, EPS $-1.65.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Stoke Therapeutics, Inc.'s revenue has grown significantly by 1,387% over the 5-year period, indicating strong business expansion. The most recent EPS of $-1.65 indicates the company is currently unprofitable.

STOK Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
24.4%
Free cash flow / Revenue

STOK Quarterly Earnings & Performance

Quarterly financial performance data for Stoke Therapeutics, Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 $4.9M -$23.5M $-0.47
Q2 2025 $4.8M -$23.5M $-0.40
Q1 2025 $4.2M -$26.4M $-0.57
Q3 2024 $3.3M -$22.5M $-0.47
Q2 2024 -$2.5M -$22.5M $-0.46
Q1 2024 $4.2M -$22.5M $-0.53
Q3 2023 $2.9M -$22.5M $-0.55
Q2 2023 -$2.5M -$22.5M $-0.63

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Stoke Therapeutics, Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
$45.6M
Cash generated from operations
Capital Expenditures
$670.0K
Investment in assets
Dividends
None
No dividend program

STOK SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Stoke Therapeutics, Inc. (CIK: 0001623526)

📋 Recent SEC Filings

Date Form Document Action
Apr 7, 2026 4 xslF345X06/form4-04072026_110410.xml View →
Apr 7, 2026 8-K d63742d8k.htm View →
Apr 3, 2026 4 xslF345X06/form4-04032026_080432.xml View →
Mar 27, 2026 8-K d119051d8k.htm View →
Mar 24, 2026 4 xslF345X06/form4-03242026_080316.xml View →

Frequently Asked Questions about STOK

What is the AI rating for STOK?

Stoke Therapeutics, Inc. (STOK) has an AI rating of BUY with 73% confidence, based on fundamental analysis of SEC EDGAR filings.

What are STOK's key strengths?

Claude: Exceptional 404% YoY revenue growth demonstrating successful product commercialization and market adoption. Positive free cash flow of $44.9M with 24.4% FCF margin despite current operating losses, indicating underlying business health.

What are the risks of investing in STOK?

Claude: Company remains operationally unprofitable with -$20.6M operating income and -11.2% operating margin despite revenue scale. Pharmaceutical sector inherent risks including regulatory approval, clinical outcome variability, and competitive pressures.

What is STOK's revenue and growth?

Stoke Therapeutics, Inc. reported revenue of $184.4M.

Does STOK pay dividends?

Stoke Therapeutics, Inc. does not currently pay dividends.

Where can I find STOK SEC filings?

Official SEC filings for Stoke Therapeutics, Inc. (CIK: 0001623526) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is STOK's EPS?

Stoke Therapeutics, Inc. has a diluted EPS of $-0.12.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is STOK a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Stoke Therapeutics, Inc. has a BUY rating with 73% confidence. The AI analysis suggests favorable fundamentals based on SEC filings. This is not investment advice.

Is STOK stock overvalued or undervalued?

Valuation metrics for STOK: ROE of -2.0% (sector avg: 15%), net margin of -3.7% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy STOK stock in 2026?

Our dual AI analysis gives Stoke Therapeutics, Inc. a combined BUY rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is STOK's free cash flow?

Stoke Therapeutics, Inc.'s operating cash flow is $45.6M, with capital expenditures of $670.0K. FCF margin is 24.4%.

How does STOK compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -3.7% (avg: 12%), ROE -2.0% (avg: 15%), current ratio 5.28 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Apr 16, 2026 | Data as of: 2025-12-31 | Powered by Claude AI