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Schrodinger, Inc. (SDGR) Stock Fundamental Analysis & AI Rating 2026

SDGR Nasdaq Pharmaceutical Preparations DE CIK: 0001490978
Recently Updated • Analysis: Apr 15, 2026 • SEC Data: 2025-12-31
SELL
72% Conf
Pending
Analysis scheduled

📊 SDGR Key Takeaways

Revenue: $255.9M
Net Margin: -40.4%
Free Cash Flow: $12.5M
Current Ratio: 2.75x
Debt/Equity: 0.00x
EPS: $-1.41
AI Rating: SELL with 72% confidence
Schrodinger, Inc. (SDGR) receives a SELL rating with 72% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $255.9M, net profit margin of -40.4%, and return on equity (ROE) of -28.4%, Schrodinger, Inc. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete SDGR stock analysis for 2026.

Is Schrodinger, Inc. (SDGR) a Good Investment?

Claude

Schrodinger exhibits weak operational fundamentals with stagnant revenue growth (0% YoY) and unsustainable operating losses (-65.2% margin, -$166.9M absolute). While the strong balance sheet ($230.5M cash, zero debt) and positive free cash flow provide near-term resilience, the absence of revenue growth and persistent large-scale losses indicate structural operational challenges that threaten long-term viability without significant strategic improvement.

Why Buy Schrodinger, Inc. Stock? SDGR Key Strengths

Claude
  • + Strong balance sheet with $230.5M cash and zero long-term debt, providing 18+ months operational runway
  • + Positive free cash flow of $12.5M despite GAAP losses, indicating non-cash charges inflate net loss
  • + Respectable gross margin of 55.7% demonstrates pricing power and product-market traction at unit level
  • + Healthy liquidity metrics (2.75x current ratio) enable flexibility to fund operations and strategic initiatives

SDGR Stock Risks: Schrodinger, Inc. Investment Risks

Claude
  • ! Stagnant revenue growth (0% YoY) in competitive pharmaceutical/biotech sector where expansion is critical
  • ! Operating losses consuming 65.2% of revenue (-$166.9M operating loss on $255.9M revenue) are unsustainable
  • ! Negative return metrics (ROE -28.4%, ROA -14.2%) indicate poor capital efficiency despite substantial equity base
  • ! Deteriorating profitability trajectory: operating losses exceed revenue, creating path-to-profitability uncertainty

Key Metrics to Watch

Claude
  • * Quarterly revenue growth rate and customer/contract pipeline growth
  • * Operating expense ratio and quarterly path toward operating breakeven
  • * Monthly cash burn rate relative to remaining cash runway
  • * Gross margin trends by segment and customer retention/churn metrics

Schrodinger, Inc. (SDGR) Financial Metrics & Key Ratios

Revenue
$255.9M
Net Income
$-103.3M
EPS (Diluted)
$-1.41
Free Cash Flow
$12.5M
Total Assets
$726.2M
Cash Position
$230.5M

💡 AI Analyst Insight

The relatively thin 4.9% FCF margin may limit capital allocation flexibility. Strong liquidity with a 2.75x current ratio provides a solid financial cushion.

SDGR Profit Margin, ROE & Profitability Analysis

Gross Margin 55.7%
Operating Margin -65.2%
Net Margin -40.4%
ROE -28.4%
ROA -14.2%
FCF Margin 4.9%

SDGR vs Healthcare Sector: How Schrodinger, Inc. Compares

How Schrodinger, Inc. compares to Healthcare sector averages

Net Margin
SDGR -40.4%
vs
Sector Avg 12.0%
SDGR Sector
ROE
SDGR -28.4%
vs
Sector Avg 15.0%
SDGR Sector
Current Ratio
SDGR 2.7x
vs
Sector Avg 2.0x
SDGR Sector
Debt/Equity
SDGR 0.0x
vs
Sector Avg 0.6x
SDGR Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Schrodinger, Inc. Stock Overvalued? SDGR Valuation Analysis 2026

Based on fundamental analysis, Schrodinger, Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-28.4%
Sector avg: 15%
Net Profit Margin
-40.4%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Schrodinger, Inc. Balance Sheet: SDGR Debt, Cash & Liquidity

Current Ratio
2.75x
Quick Ratio
2.75x
Debt/Equity
0.00x
Debt/Assets
49.9%
Interest Coverage
N/A
Long-term Debt
N/A

SDGR Revenue & Earnings Growth: 5-Year Financial Trend

SDGR 5-year financial data: Year 2020: Revenue $108.1M, Net Income N/A, EPS N/A. Year 2021: Revenue $137.9M, Net Income -$24.6M, EPS N/A. Year 2023: Revenue $216.7M, Net Income -$100.4M, EPS $-1.42. Year 2024: Revenue $216.7M, Net Income -$149.2M, EPS $-2.10. Year 2025: Revenue $255.9M, Net Income $40.7M, EPS $0.54.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Schrodinger, Inc.'s revenue has grown significantly by 137% over the 5-year period, indicating strong business expansion. The most recent EPS of $0.54 reflects profitable operations.

SDGR Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
4.9%
Free cash flow / Revenue

SDGR Quarterly Earnings & Performance

Quarterly financial performance data for Schrodinger, Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 $35.3M -$32.8M $-0.45
Q2 2025 $47.3M -$43.2M $-0.59
Q1 2025 $36.6M -$54.7M $-0.76
Q3 2024 $35.3M $4.3M $-0.52
Q2 2024 $35.2M $4.3M $0.06
Q1 2024 $36.6M -$54.7M $-0.76
Q3 2023 $37.0M $4.3M $-0.56
Q2 2023 $35.2M $4.3M $0.06

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Schrodinger, Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
$13.9M
Cash generated from operations
Capital Expenditures
$1.4M
Investment in assets
Dividends
None
No dividend program

SDGR SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Schrodinger, Inc. (CIK: 0001490978)

📋 Recent SEC Filings

Date Form Document Action
Mar 12, 2026 8-K sdgr-20260306.htm View →
Mar 6, 2026 4 xslF345X05/wk-form4_1772836184.xml View →
Mar 6, 2026 4 xslF345X05/wk-form4_1772836142.xml View →
Mar 6, 2026 4 xslF345X05/wk-form4_1772836115.xml View →
Mar 6, 2026 4 xslF345X05/wk-form4_1772836083.xml View →

Frequently Asked Questions about SDGR

What is the AI rating for SDGR?

Schrodinger, Inc. (SDGR) has an AI rating of SELL with 72% confidence, based on fundamental analysis of SEC EDGAR filings.

What are SDGR's key strengths?

Claude: Strong balance sheet with $230.5M cash and zero long-term debt, providing 18+ months operational runway. Positive free cash flow of $12.5M despite GAAP losses, indicating non-cash charges inflate net loss.

What are the risks of investing in SDGR?

Claude: Stagnant revenue growth (0% YoY) in competitive pharmaceutical/biotech sector where expansion is critical. Operating losses consuming 65.2% of revenue (-$166.9M operating loss on $255.9M revenue) are unsustainable.

What is SDGR's revenue and growth?

Schrodinger, Inc. reported revenue of $255.9M.

Does SDGR pay dividends?

Schrodinger, Inc. does not currently pay dividends.

Where can I find SDGR SEC filings?

Official SEC filings for Schrodinger, Inc. (CIK: 0001490978) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is SDGR's EPS?

Schrodinger, Inc. has a diluted EPS of $-1.41.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is SDGR a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Schrodinger, Inc. has a SELL rating with 72% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is SDGR stock overvalued or undervalued?

Valuation metrics for SDGR: ROE of -28.4% (sector avg: 15%), net margin of -40.4% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy SDGR stock in 2026?

Our dual AI analysis gives Schrodinger, Inc. a combined SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is SDGR's free cash flow?

Schrodinger, Inc.'s operating cash flow is $13.9M, with capital expenditures of $1.4M. FCF margin is 4.9%.

How does SDGR compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -40.4% (avg: 12%), ROE -28.4% (avg: 15%), current ratio 2.75 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Apr 15, 2026 | Data as of: 2025-12-31 | Powered by Claude AI