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Pfizer Inc. (PFE) Stock Fundamental Analysis & AI Rating 2026

PFE NYSE Pharmaceutical Preparations DE CIK: 0000078003
Recently Updated • Analysis: Apr 14, 2026 • SEC Data: 2025-12-31
SELL
72% Conf
Pending
Analysis scheduled

📊 PFE Key Takeaways

Revenue: $62.6B
Net Margin: 12.4%
Free Cash Flow: $9.1B
Current Ratio: 1.16x
Debt/Equity: 0.71x
EPS: $1.36
AI Rating: SELL with 72% confidence
Pfizer Inc. (PFE) receives a SELL rating with 72% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $62.6B, net profit margin of 12.4%, and return on equity (ROE) of 9.0%, Pfizer Inc. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete PFE stock analysis for 2026.

Is Pfizer Inc. (PFE) a Good Investment?

Claude

Pfizer exhibits concerning fundamental deterioration with declining revenue (-1.6% YoY), flat net income growth, and weakening earnings per share (-3.5% YoY), despite maintaining positive free cash flow. The company faces significant headwinds: tight liquidity (0.87x quick ratio), elevated leverage with $61.6B long-term debt, low returns on equity (9.0%), and marginal interest coverage (2.8x), indicating limited financial flexibility and poor capital efficiency.

Why Buy Pfizer Inc. Stock? PFE Key Strengths

Claude
  • + Strong free cash flow generation at $9.1B with 14.5% FCF margin
  • + Solid operating cash flow of $11.7B demonstrates underlying business cash generation
  • + Reasonable net profit margin of 12.4% maintains profitability despite revenue pressure

PFE Stock Risks: Pfizer Inc. Investment Risks

Claude
  • ! Revenue contraction (-1.6% YoY) signals loss of market share or declining product demand
  • ! Liquidity constraints with quick ratio of 0.87x and minimal cash position ($1.1B relative to $208B assets)
  • ! Weak capital returns with ROE of 9.0% and ROA of 3.7% indicate poor asset utilization and shareholder value creation
  • ! Interest coverage ratio of 2.8x limits financial flexibility given $61.6B debt burden
  • ! EPS decline of 3.5% YoY despite flat net income suggests dilution from share count or one-time items

Key Metrics to Watch

Claude
  • * Quarterly revenue trends and product pipeline commercial success
  • * Operating cash flow sustainability and FCF conversion rate
  • * Debt reduction trajectory and leverage ratio improvement
  • * Return on equity improvement and capital allocation efficiency

Pfizer Inc. (PFE) Financial Metrics & Key Ratios

Revenue
$62.6B
Net Income
$7.8B
EPS (Diluted)
$1.36
Free Cash Flow
$9.1B
Total Assets
$208.2B
Cash Position
$1.1B

💡 AI Analyst Insight

Pfizer Inc. presents a mixed fundamental picture. Review the detailed metrics above to form your own investment thesis.

PFE Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin 12.0%
Net Margin 12.4%
ROE 9.0%
ROA 3.7%
FCF Margin 14.5%

PFE vs Healthcare Sector: How Pfizer Inc. Compares

How Pfizer Inc. compares to Healthcare sector averages

Net Margin
PFE 12.4%
vs
Sector Avg 12.0%
PFE Sector
ROE
PFE 9.0%
vs
Sector Avg 15.0%
PFE Sector
Current Ratio
PFE 1.2x
vs
Sector Avg 2.0x
PFE Sector
Debt/Equity
PFE 0.7x
vs
Sector Avg 0.6x
PFE Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Pfizer Inc. Stock Overvalued? PFE Valuation Analysis 2026

Based on fundamental analysis, Pfizer Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
9.0%
Sector avg: 15%
Net Profit Margin
12.4%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.71x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Pfizer Inc. Balance Sheet: PFE Debt, Cash & Liquidity

Current Ratio
1.16x
Quick Ratio
0.87x
Debt/Equity
0.71x
Debt/Assets
58.3%
Interest Coverage
2.82x
Long-term Debt
$61.6B

PFE Revenue & Earnings Growth: 5-Year Financial Trend

PFE 5-year financial data: Year 2018: Revenue $53.6B, Net Income N/A, EPS N/A. Year 2019: Revenue $53.6B, Net Income N/A, EPS N/A. Year 2020: Revenue $41.9B, Net Income N/A, EPS N/A. Year 2021: Revenue $81.3B, Net Income $16.0B, EPS $2.82. Year 2023: Revenue $91.8B, Net Income $22.0B, EPS $3.85.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Pfizer Inc.'s revenue has grown significantly by 71% over the 5-year period, indicating strong business expansion. The most recent EPS of $0.37 reflects profitable operations.

PFE Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
14.5%
Free cash flow / Revenue

PFE Quarterly Earnings & Performance

Quarterly financial performance data for Pfizer Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 $16.7B $3.5B $0.62
Q2 2025 $13.3B $41.0M $0.01
Q1 2025 $13.7B $3.0B $0.52
Q3 2024 $13.5B -$2.4B $-0.42
Q2 2024 $13.0B $41.0M $0.01
Q1 2024 $14.9B $3.1B $0.55
Q3 2023 $13.2B -$2.4B $-0.42
Q2 2023 $12.7B $2.3B $0.41

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Pfizer Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
$11.7B
Cash generated from operations
Capital Expenditures
$2.6B
Investment in assets
Dividends
None
No dividend program

PFE SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Pfizer Inc. (CIK: 0000078003)

📋 Recent SEC Filings

Date Form Document Action
Apr 16, 2026 4 xslF345X06/doc4.xml View →
Apr 1, 2026 4 xslF345X06/doc4.xml View →
Mar 30, 2026 4 xslF345X06/doc4.xml View →
Mar 30, 2026 4 xslF345X06/doc4.xml View →
Mar 30, 2026 4 xslF345X06/doc4.xml View →

Frequently Asked Questions about PFE

What is the AI rating for PFE?

Pfizer Inc. (PFE) has an AI rating of SELL with 72% confidence, based on fundamental analysis of SEC EDGAR filings.

What are PFE's key strengths?

Claude: Strong free cash flow generation at $9.1B with 14.5% FCF margin. Solid operating cash flow of $11.7B demonstrates underlying business cash generation.

What are the risks of investing in PFE?

Claude: Revenue contraction (-1.6% YoY) signals loss of market share or declining product demand. Liquidity constraints with quick ratio of 0.87x and minimal cash position ($1.1B relative to $208B assets).

What is PFE's revenue and growth?

Pfizer Inc. reported revenue of $62.6B.

Does PFE pay dividends?

Pfizer Inc. does not currently pay dividends.

Where can I find PFE SEC filings?

Official SEC filings for Pfizer Inc. (CIK: 0000078003) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is PFE's EPS?

Pfizer Inc. has a diluted EPS of $1.36.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is PFE a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Pfizer Inc. has a SELL rating with 72% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is PFE stock overvalued or undervalued?

Valuation metrics for PFE: ROE of 9.0% (sector avg: 15%), net margin of 12.4% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy PFE stock in 2026?

Our dual AI analysis gives Pfizer Inc. a combined SELL rating for 2026. Revenue is data pending, with profitability above sector average. Always conduct your own research.

What is PFE's free cash flow?

Pfizer Inc.'s operating cash flow is $11.7B, with capital expenditures of $2.6B. FCF margin is 14.5%.

How does PFE compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin 12.4% (avg: 12%), ROE 9.0% (avg: 15%), current ratio 1.16 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Apr 14, 2026 | Data as of: 2025-12-31 | Powered by Claude AI