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Neurogene Inc. (NGNE) Stock Fundamental Analysis & AI Rating 2026

NGNE Nasdaq Pharmaceutical Preparations CIK: 0001404644
Recently Updated • Analysis: Apr 13, 2026 • SEC Data: 2025-12-31
Combined AI Rating
SELL
74% Confidence
AGREEMENT
SELL
85% Conf
HOLD
63% Conf

📊 NGNE Key Takeaways

Revenue: $0.0
Net Margin: N/A
Free Cash Flow: $-78.4M
Current Ratio: 16.56x
Debt/Equity: 0.00x
EPS: $-4.24
AI Rating: SELL with 85% confidence
Neurogene Inc. (NGNE) receives a SELL rating with 74% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $0, and return on equity (ROE) of -34.1%, Neurogene Inc. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete NGNE stock analysis for 2026.

Is Neurogene Inc. (NGNE) a Good Investment?

Claude

Neurogene is a pre-revenue pharmaceutical development stage company with significant operating losses (-$103.3M) and substantial cash burn (-$78.4M FCF), providing only ~1.3 years of cash runway at current burn rates. While the company maintains a strong balance sheet with $103.8M cash and no meaningful debt, and losses are improving modestly year-over-year, the absence of commercial revenue and high execution risk make fundamental valuation untenable until pipeline progress demonstrates viability.

ChatGPT

Neurogene is a pre-revenue developer with a strong balance sheet—ample cash, minimal liabilities, and no debt—providing a reasonable runway to progress programs. However, operating losses and cash burn remain substantial and net losses appear elevated year over year. Until there is clear evidence of clinical milestones translating into partnerships or initial revenue, fundamentals are neutral.

Why Buy Neurogene Inc. Stock? NGNE Key Strengths

Claude
  • + Strong liquidity position with $103.8M cash and 16.56x current ratio
  • + Clean capital structure with zero long-term debt and minimal liabilities
  • + Net losses improving 20.2% YoY indicating potential progress toward profitability
  • + Moderate insider trading activity (15 Form 4 filings in 90 days) suggests engagement
ChatGPT
  • + Robust liquidity and 16.56x current ratio
  • + No long-term debt and low liabilities
  • + Large equity base relative to assets/liabilities

NGNE Stock Risks: Neurogene Inc. Investment Risks

Claude
  • ! Pre-revenue stage with zero commercial sales generating complete pipeline dependency
  • ! Cash runway of approximately 1.3 years at current -$77.2M annual operating burn rate
  • ! Negative return on equity (-34.1%) and assets (-31.3%) indicating capital inefficiency
  • ! All profitability metrics non-existent; company survival contingent on pipeline approval and commercialization
ChatGPT
  • ! Zero revenue with continued large net losses
  • ! High operating cash burn shortening runway
  • ! Execution/clinical and financing risk leading to potential dilution

Key Metrics to Watch

Claude
  • * Quarterly cash burn rate trend and cash balance depletion schedule
  • * Clinical pipeline advancement milestones and regulatory approval progress
  • * Operating expense management and ability to extend runway through fundraising
ChatGPT
  • * Cash & equivalents
  • * Operating cash flow (burn rate)

Neurogene Inc. (NGNE) Financial Metrics & Key Ratios

Revenue
$0.0
Net Income
$-90.4M
EPS (Diluted)
$-4.24
Free Cash Flow
$-78.4M
Total Assets
$288.6M
Cash Position
$103.8M

💡 AI Analyst Insight

Strong liquidity with a 16.56x current ratio provides a solid financial cushion.

NGNE Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin N/A
Net Margin N/A
ROE -34.1%
ROA -31.3%
FCF Margin N/A

NGNE vs Healthcare Sector: How Neurogene Inc. Compares

How Neurogene Inc. compares to Healthcare sector averages

Net Margin
NGNE 0.0%
vs
Sector Avg 12.0%
NGNE Sector
ROE
NGNE -34.1%
vs
Sector Avg 15.0%
NGNE Sector
Current Ratio
NGNE 16.6x
vs
Sector Avg 2.0x
NGNE Sector
Debt/Equity
NGNE 0.0x
vs
Sector Avg 0.6x
NGNE Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Neurogene Inc. Stock Overvalued? NGNE Valuation Analysis 2026

Based on fundamental analysis, Neurogene Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-34.1%
Sector avg: 15%
Net Profit Margin
N/A
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Neurogene Inc. Balance Sheet: NGNE Debt, Cash & Liquidity

Current Ratio
16.56x
Quick Ratio
16.56x
Debt/Equity
0.00x
Debt/Assets
8.2%
Interest Coverage
-34,442.67x
Long-term Debt
N/A

NGNE Revenue & Earnings Growth: 5-Year Financial Trend

NGNE 5-year financial data: Year 2018: Revenue $25.0M, Net Income N/A, EPS N/A. Year 2019: Revenue $25.0M, Net Income N/A, EPS N/A. Year 2024: Revenue $925.0K, Net Income -$36.3M, EPS $2.93. Year 2025: Revenue $925.0K, Net Income -$75.1M, EPS $-4.28.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Neurogene Inc.'s revenue has declined by 96% over the 5-year period, indicating business contraction. The most recent EPS of $-4.28 indicates the company is currently unprofitable.

NGNE Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
N/A
Free cash flow / Revenue

NGNE Quarterly Earnings & Performance

Quarterly financial performance data for Neurogene Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 N/A -$16.9M $-0.99
Q2 2025 N/A -$16.9M $-1.05
Q3 2024 N/A -$11.9M $-1.19
Q2 2024 N/A -$11.9M $-1.09
Q3 2019 $25.0M -$15.0M N/A
Q2 2019 $25.0M -$1.0K $-0.09
Q3 2018 $25.0M -$11.8M N/A
Q2 2018 $25.0M $2.9M $0.12

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Neurogene Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$77.2M
Cash generated from operations
Stock Buybacks
$350
Shares repurchased (TTM)
Capital Expenditures
$1.2M
Investment in assets
Dividends
None
No dividend program

NGNE SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Neurogene Inc. (CIK: 0001404644)

📋 Recent SEC Filings

Date Form Document Action
Mar 30, 2026 4 xslF345X06/wk-form4_1774905421.xml View →
Mar 30, 2026 4 xslF345X06/wk-form4_1774905414.xml View →
Mar 30, 2026 4 xslF345X06/wk-form4_1774905406.xml View →
Mar 24, 2026 10-K ngne-20251231.htm View →
Mar 24, 2026 8-K ngne-20260324.htm View →

Frequently Asked Questions about NGNE

What is the AI rating for NGNE?

Neurogene Inc. (NGNE) has a Combined AI Rating of SELL from Claude (SELL) and ChatGPT (HOLD) with 74% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are NGNE's key strengths?

Claude: Strong liquidity position with $103.8M cash and 16.56x current ratio. Clean capital structure with zero long-term debt and minimal liabilities. ChatGPT: Robust liquidity and 16.56x current ratio. No long-term debt and low liabilities.

What are the risks of investing in NGNE?

Claude: Pre-revenue stage with zero commercial sales generating complete pipeline dependency. Cash runway of approximately 1.3 years at current -$77.2M annual operating burn rate. ChatGPT: Zero revenue with continued large net losses. High operating cash burn shortening runway.

What is NGNE's revenue and growth?

Neurogene Inc. reported revenue of $0.0.

Does NGNE pay dividends?

Neurogene Inc. does not currently pay dividends.

Where can I find NGNE SEC filings?

Official SEC filings for Neurogene Inc. (CIK: 0001404644) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is NGNE's EPS?

Neurogene Inc. has a diluted EPS of $-4.24.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is NGNE a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Neurogene Inc. has a SELL rating with 74% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is NGNE stock overvalued or undervalued?

Valuation metrics for NGNE: ROE of -34.1% (sector avg: 15%), net margin of N/A (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy NGNE stock in 2026?

Our dual AI analysis gives Neurogene Inc. a combined SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is NGNE's free cash flow?

Neurogene Inc.'s operating cash flow is $-77.2M, with capital expenditures of $1.2M.

How does NGNE compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin N/A (avg: 12%), ROE -34.1% (avg: 15%), current ratio 16.56 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Apr 13, 2026 | Data as of: 2025-12-31 | Powered by Claude AI