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Matinas BioPharma Holdings, Inc. (MTNB) Stock Fundamental Analysis & AI Rating 2026

MTNB NYSE Pharmaceutical Preparations DE CIK: 0001582554
Updated This Month • Analysis: Apr 2, 2026 • SEC Data: 2025-12-31
Combined AI Rating
STRONG SELL
87% Confidence
STRONG AGREEMENT
STRONG SELL
92% Conf
STRONG SELL
82% Conf

📊 MTNB Key Takeaways

Revenue: $1.1M
Net Margin: -943.9%
Free Cash Flow: $-7.2M
Current Ratio: 2.79x
Debt/Equity: 0.00x
EPS: $-2.00
AI Rating: STRONG SELL with 92% confidence
Matinas BioPharma Holdings, Inc. (MTNB) receives a STRONG SELL rating with 87% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $1.1M, net profit margin of -943.9%, and return on equity (ROE) of -214.2%, Matinas BioPharma Holdings, Inc. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete MTNB stock analysis for 2026.

Is Matinas BioPharma Holdings, Inc. (MTNB) a Good Investment?

Claude

Matinas BioPharma is in severe financial distress with revenue collapsing 65.6% YoY to just $1.1M while burning $7M in operating cash flow quarterly. The company's negative gross profit structure, extreme operating margin of -635%, and rapidly depleting cash position indicate an unsustainable business model nearing a critical funding crisis.

ChatGPT

Revenue has collapsed and margins remain deeply negative, with operating cash burn far exceeding the company’s $4M cash balance, implying a short runway. Although debt-free with a decent current ratio, fundamentals point to continued losses and a high likelihood of near-term dilution absent meaningful, recurring revenue.

Why Buy Matinas BioPharma Holdings, Inc. Stock? MTNB Key Strengths

Claude
  • + Maintains positive stockholders equity of $4.8M providing limited balance sheet cushion
  • + Current ratio of 2.79x indicates short-term liquidity to cover immediate liabilities
  • + Zero long-term debt eliminates refinancing risk
ChatGPT
  • + Debt-free balance sheet
  • + Solid current ratio (~2.8x)
  • + Net loss/EPS improved YoY

MTNB Stock Risks: Matinas BioPharma Holdings, Inc. Investment Risks

Claude
  • ! Revenue decline of 65.6% YoY signals complete loss of market traction and commercial viability
  • ! Quarterly operating cash burn of $7M with only $4M cash remaining translates to <2 quarters of runway
  • ! Massive negative margins (-943.9% net margin, -635% operating margin) indicate structural unprofitability with no clear path to positive returns
  • ! No insider buying activity in last 90 days suggests management has no confidence in turnaround
  • ! Clinical-stage pharma company with near-zero revenue indicating pipeline failure and failed commercialization
ChatGPT
  • ! Short cash runway and dilution risk
  • ! Sharp revenue decline and limited recurring revenue
  • ! Persistently negative margins and ROE

Key Metrics to Watch

Claude
  • * Monthly cash burn rate and remaining cash runway
  • * Pipeline advancement and clinical trial outcomes
  • * Quarterly revenue stabilization or further deterioration
  • * Financing activities and dilution events
  • * Operating expense reduction measures
ChatGPT
  • * Quarterly operating cash burn and runway
  • * Collaboration/grant revenue (non-dilutive funding)

Matinas BioPharma Holdings, Inc. (MTNB) Financial Metrics & Key Ratios

Revenue
$1.1M
Net Income
$-10.3M
EPS (Diluted)
$-2.00
Free Cash Flow
$-7.2M
Total Assets
$7.2M
Cash Position
$4.0M

💡 AI Analyst Insight

Strong liquidity with a 2.79x current ratio provides a solid financial cushion.

MTNB Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin -635.0%
Net Margin -943.9%
ROE -214.2%
ROA -143.5%
FCF Margin -659.6%

MTNB vs Healthcare Sector: How Matinas BioPharma Holdings, Inc. Compares

How Matinas BioPharma Holdings, Inc. compares to Healthcare sector averages

Net Margin
MTNB -943.9%
vs
Sector Avg 12.0%
MTNB Sector
ROE
MTNB -214.2%
vs
Sector Avg 15.0%
MTNB Sector
Current Ratio
MTNB 2.8x
vs
Sector Avg 2.0x
MTNB Sector
Debt/Equity
MTNB 0.0x
vs
Sector Avg 0.6x
MTNB Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Matinas BioPharma Holdings, Inc. Stock Overvalued? MTNB Valuation Analysis 2026

Based on fundamental analysis, Matinas BioPharma Holdings, Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-214.2%
Sector avg: 15%
Net Profit Margin
-943.9%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Matinas BioPharma Holdings, Inc. Balance Sheet: MTNB Debt, Cash & Liquidity

Current Ratio
2.79x
Quick Ratio
2.79x
Debt/Equity
0.00x
Debt/Assets
33.0%
Interest Coverage
N/A
Long-term Debt
N/A

MTNB Revenue & Earnings Growth: 5-Year Financial Trend

MTNB 5-year financial data: Year 2020: Revenue $158.3K, Net Income N/A, EPS N/A. Year 2021: Revenue $158.3K, Net Income -$22.4M, EPS N/A. Year 2022: Revenue $3.2M, Net Income -$23.3M, EPS N/A. Year 2023: Revenue $3.2M, Net Income -$21.0M, EPS $-0.10. Year 2024: Revenue $1.1M, Net Income -$22.9M, EPS $-5.28.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Matinas BioPharma Holdings, Inc.'s revenue has grown significantly by 592% over the 5-year period, indicating strong business expansion. The most recent EPS of $-4.98 indicates the company is currently unprofitable.

MTNB Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-659.6%
Free cash flow / Revenue

MTNB Quarterly Earnings & Performance

Quarterly financial performance data for Matinas BioPharma Holdings, Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2024 $1.1M -$4.3M $-0.85
Q2 2024 $1.1M -$5.7M $-0.02
Q1 2024 $1.1M -$5.5M $-0.03
Q3 2023 $1.1M -$5.5M $-0.03
Q2 2023 $1.1M -$5.9M $-0.03
Q1 2023 $1.1M -$5.5M N/A
Q3 2022 $33.3K -$5.5M N/A
Q2 2022 $33.3K -$4.8M N/A

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Matinas BioPharma Holdings, Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$7.0M
Cash generated from operations
Capital Expenditures
$218.0K
Investment in assets
Dividends
None
No dividend program

MTNB SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Matinas BioPharma Holdings, Inc. (CIK: 0001582554)

📋 Recent SEC Filings

Date Form Document Action
Apr 3, 2026 8-K form8-k.htm View →
Mar 31, 2026 10-K form10-k.htm View →
Jan 23, 2026 8-K form8-k.htm View →
Dec 12, 2025 8-K form8-k.htm View →
Nov 21, 2025 8-K form8-k.htm View →

Frequently Asked Questions about MTNB

What is the AI rating for MTNB?

Matinas BioPharma Holdings, Inc. (MTNB) has a Combined AI Rating of STRONG SELL from Claude (STRONG SELL) and ChatGPT (STRONG SELL) with 87% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are MTNB's key strengths?

Claude: Maintains positive stockholders equity of $4.8M providing limited balance sheet cushion. Current ratio of 2.79x indicates short-term liquidity to cover immediate liabilities. ChatGPT: Debt-free balance sheet. Solid current ratio (~2.8x).

What are the risks of investing in MTNB?

Claude: Revenue decline of 65.6% YoY signals complete loss of market traction and commercial viability. Quarterly operating cash burn of $7M with only $4M cash remaining translates to <2 quarters of runway. ChatGPT: Short cash runway and dilution risk. Sharp revenue decline and limited recurring revenue.

What is MTNB's revenue and growth?

Matinas BioPharma Holdings, Inc. reported revenue of $1.1M.

Does MTNB pay dividends?

Matinas BioPharma Holdings, Inc. does not currently pay dividends.

Where can I find MTNB SEC filings?

Official SEC filings for Matinas BioPharma Holdings, Inc. (CIK: 0001582554) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is MTNB's EPS?

Matinas BioPharma Holdings, Inc. has a diluted EPS of $-2.00.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is MTNB a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Matinas BioPharma Holdings, Inc. has a STRONG SELL rating with 87% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is MTNB stock overvalued or undervalued?

Valuation metrics for MTNB: ROE of -214.2% (sector avg: 15%), net margin of -943.9% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy MTNB stock in 2026?

Our dual AI analysis gives Matinas BioPharma Holdings, Inc. a combined STRONG SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is MTNB's free cash flow?

Matinas BioPharma Holdings, Inc.'s operating cash flow is $-7.0M, with capital expenditures of $218.0K. FCF margin is -659.6%.

How does MTNB compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -943.9% (avg: 12%), ROE -214.2% (avg: 15%), current ratio 2.79 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Apr 2, 2026 | Data as of: 2025-12-31 | Powered by Claude AI