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Lixte Biotechnology Holdings, Inc.. (LIXT) Fundamental Analysis & AI Grade 2026

LIXT Nasdaq Pharmaceutical Preparations DE CIK: 0001335105
Updated This Month • Analysis: May 15, 2026 • SEC Data: 2026-03-31
Combined AI Grade
C
78% Confidence
AGREEMENT
D
78% Conf
C
78% Conf

📊 LIXT Key Takeaways

Revenue: $200.0K
Net Margin: -970.8%
Free Cash Flow: $-1.8M
Current Ratio: 2.78x
Debt/Equity: 0.00x
EPS: $-0.18
AI Grade: D with 78% confidence
Lixte Biotechnology Holdings, Inc.. (LIXT) receives a C fundamental grade with 78% confidence from our AI analysis based on SEC 10-K filings. With revenue of $200.0K, net profit margin of -970.8%, and return on equity (ROE) of -24.4%, Lixte Biotechnology Holdings, Inc.. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete LIXT stock analysis for 2026.

Is Lixte Biotechnology Holdings, Inc.. (LIXT) a Good Investment?

Claude

LIXT is a pre-commercial biotech firm burning $1.8M in quarterly operating cash against only $200K in revenue, with approximately 6-7 months of cash runway remaining despite maintaining a debt-free balance sheet. Absent near-term successful product commercialization, strategic partnerships, or capital raise announcements, the company faces acute funding risk and potential equity depletion within two quarters.

ChatGPT

Fundamentals indicate a pre‑commercial biotech with minimal revenue and extremely negative margins, ROE, and ROA. Liquidity is solid and the balance sheet is debt‑free, but the current cash burn implies a limited runway and likely need for external financing. Until operating losses narrow materially or recurring revenue emerges, downside risk from dilution and execution remains high.

Lixte Biotechnology Holdings, Inc.. Key Strengths (LIXT)

Claude
  • + Debt-free balance sheet with zero long-term debt and positive stockholders' equity of $7.9M
  • + Strong liquidity position with 2.78x current ratio providing near-term operational flexibility
  • + 6 Form 4 insider filings in 90 days indicate continued insider engagement
ChatGPT
  • + Debt-free balance sheet
  • + Strong liquidity (current ratio ~3.9x)
  • + Positive equity relative to low liabilities

LIXT Stock Risks: Lixte Biotechnology Holdings, Inc.. Investment Risks

Claude
  • ! Critical cash runway depletion: $3.3M reserve at $1.8M quarterly burn rate leaves 6-7 months of operational capacity before funding crisis
  • ! Pre-commercial revenue stage: $200K quarterly revenue indicates zero successful product commercialization and non-viable business model at current scale
  • ! Structural operating losses: -993.7% operating margin and -970.8% net margin reflect fundamental inability to generate positive unit economics
ChatGPT
  • ! Sustained operating losses with minimal revenue base
  • ! Cash burn likely necessitating dilutive financing
  • ! Execution/clinical milestone risk impacting funding and timing

Key Metrics to Watch

Claude
  • * Quarterly cash balance and monthly burn rate trend
  • * Product revenue growth and commercialization progress
  • * Capital raise announcements, partnerships, or strategic transactions
ChatGPT
  • * Operating cash burn (OCF)
  • * Cash and equivalents / runway months

Lixte Biotechnology Holdings, Inc.. (LIXT) Financial Metrics & Key Ratios

Revenue
$200.0K
Net Income
$-1.9M
EPS (Diluted)
$-0.18
Free Cash Flow
$-1.8M
Total Assets
$10.9M
Cash Position
$3.3M

💡 AI Analyst Insight

Strong liquidity with a 2.78x current ratio provides a solid financial cushion.

LIXT Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin -993.7%
Net Margin -970.8%
ROE -24.4%
ROA -17.9%
FCF Margin -915.7%

LIXT vs Healthcare Sector: How Lixte Biotechnology Holdings, Inc.. Compares

How Lixte Biotechnology Holdings, Inc.. compares to Healthcare sector averages

Net Margin
LIXT -970.8%
vs
Sector Avg 12.0%
LIXT Sector
ROE
LIXT -24.4%
vs
Sector Avg 15.0%
LIXT Sector
Current Ratio
LIXT 2.8x
vs
Sector Avg 2.0x
LIXT Sector
Debt/Equity
LIXT 0.0x
vs
Sector Avg 0.6x
LIXT Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Lixte Biotechnology Holdings, Inc.. Stock Overvalued? LIXT Valuation Analysis 2026

Based on fundamental analysis, Lixte Biotechnology Holdings, Inc.. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-24.4%
Sector avg: 15%
Net Profit Margin
-970.8%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Lixte Biotechnology Holdings, Inc.. Balance Sheet: LIXT Debt, Cash & Liquidity

Current Ratio
2.78x
Quick Ratio
2.78x
Debt/Equity
0.00x
Debt/Assets
15.5%
Interest Coverage
-641.93x
Long-term Debt
N/A

LIXT Revenue & Earnings Growth: 5-Year Financial Trend

LIXT 5-year financial data: Year 2011: Revenue $0, Net Income N/A, EPS N/A. Year 2012: Revenue $0, Net Income N/A, EPS N/A. Year 2013: Revenue $0, Net Income N/A, EPS N/A. Year 2015: Revenue $200.0K, Net Income N/A, EPS N/A.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Lixte Biotechnology Holdings, Inc..'s revenue has remained relatively flat over the 5-year period, with a 0% decline. The most recent EPS of $-1.59 indicates the company is currently unprofitable.

LIXT Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-915.7%
Free cash flow / Revenue

LIXT Quarterly Earnings & Performance

Quarterly financial performance data for Lixte Biotechnology Holdings, Inc.. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2013 N/A -$16.1K N/A
Q2 2013 N/A -$16.1K N/A
Q1 2013 N/A -$16.1K N/A
Q3 2012 N/A -$16.1K N/A
Q2 2012 N/A -$16.1K N/A
Q1 2012 N/A -$16.1K N/A
Q3 2011 N/A -$16.1K N/A
Q2 2011 N/A -$16.1K N/A

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Lixte Biotechnology Holdings, Inc.. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$1.8M
Cash generated from operations
Stock Buybacks
$24.7K
Shares repurchased (TTM)
Dividends
None
No dividend program

LIXT SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Lixte Biotechnology Holdings, Inc.. (CIK: 0001335105)

📋 Recent SEC Filings

Date Form Document Action
Jun 4, 2026 8-K form8-k.htm View →
Jun 1, 2026 4 xslF345X06/ownership.xml View →
Jun 1, 2026 8-K form8-k.htm View →
May 14, 2026 10-Q form10-q.htm View →
Apr 17, 2026 4 xslF345X06/ownership.xml View →

Frequently Asked Questions about LIXT

What is the AI rating for LIXT?

Lixte Biotechnology Holdings, Inc.. (LIXT) has a Combined AI Grade of C from Claude (D) and ChatGPT (C) with 78% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are LIXT's key strengths?

Claude: Debt-free balance sheet with zero long-term debt and positive stockholders' equity of $7.9M. Strong liquidity position with 2.78x current ratio providing near-term operational flexibility. ChatGPT: Debt-free balance sheet. Strong liquidity (current ratio ~3.9x).

What are the risks of investing in LIXT?

Claude: Critical cash runway depletion: $3.3M reserve at $1.8M quarterly burn rate leaves 6-7 months of operational capacity before funding crisis. Pre-commercial revenue stage: $200K quarterly revenue indicates zero successful product commercialization and non-viable business model at current scale. ChatGPT: Sustained operating losses with minimal revenue base. Cash burn likely necessitating dilutive financing.

What is LIXT's revenue and growth?

Lixte Biotechnology Holdings, Inc.. reported revenue of $200.0K.

Does LIXT pay dividends?

Lixte Biotechnology Holdings, Inc.. does not currently pay dividends.

Where can I find LIXT SEC filings?

Official SEC filings for Lixte Biotechnology Holdings, Inc.. (CIK: 0001335105) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is LIXT's EPS?

Lixte Biotechnology Holdings, Inc.. has a diluted EPS of $-0.18.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined grade reflects both perspectives for balanced insights.

What is LIXT's fundamental grade?

Based on our AI fundamental analysis in June 2026, Lixte Biotechnology Holdings, Inc.. has a C grade with 78% confidence. Review the strengths and risks sections above for full context. This is not investment advice.

Is LIXT stock overvalued or undervalued?

Valuation metrics for LIXT: ROE of -24.4% (sector avg: 15%), net margin of -970.8% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

What is LIXT's AI grade for 2026?

Our dual AI analysis gives Lixte Biotechnology Holdings, Inc.. a combined C grade for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is LIXT's free cash flow?

Lixte Biotechnology Holdings, Inc..'s operating cash flow is $-1.8M, with capital expenditures of N/A. FCF margin is -915.7%.

How does LIXT compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -970.8% (avg: 12%), ROE -24.4% (avg: 15%), current ratio 2.78 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: May 15, 2026 | Data as of: 2026-03-31 | Powered by Claude AI