← Back to All US Stocks

Kezar Life Sciences, Inc. (KZR) Stock Fundamental Analysis & AI Rating 2026

KZR Nasdaq Pharmaceutical Preparations DE CIK: 0001645666
Recently Updated • Analysis: Apr 12, 2026 • SEC Data: 2025-12-31
Combined AI Rating
SELL
70% Confidence
AGREEMENT
HOLD
68% Conf
SELL
72% Conf

📊 KZR Key Takeaways

Revenue: $0.0
Net Margin: N/A
Free Cash Flow: $-51.8M
Current Ratio: 11.52x
Debt/Equity: 0.00x
EPS: $-7.66
AI Rating: HOLD with 68% confidence
Kezar Life Sciences, Inc. (KZR) receives a SELL rating with 70% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $0, and return on equity (ROE) of -80.0%, Kezar Life Sciences, Inc. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete KZR stock analysis for 2026.

Is Kezar Life Sciences, Inc. (KZR) a Good Investment?

Claude

Kezar Life Sciences presents a paradoxical fundamental profile: exceptional financial health with $71.9M cash, zero debt, and improving operational losses, yet faces acute execution risk as a pre-revenue pharmaceutical company with ~16 months of runway at current burn rates. The solid balance sheet provides strategic flexibility, but the outcome depends entirely on clinical trial success and FDA approvals rather than operational fundamentals.

ChatGPT

Kezar is a pre-revenue biotech with sustained operating losses and negative free cash flow, offset by a sizable cash balance and no debt. At the current burn (~$52M OCF) versus ~$72M cash, liquidity covers roughly 12–18 months before likely external financing is needed. Despite YoY loss improvement, fundamentals show no near-term path to profitability or revenue.

Why Buy Kezar Life Sciences, Inc. Stock? KZR Key Strengths

Claude
  • + Exceptional liquidity with $71.9M cash reserve against only $6.6M liabilities, providing substantial operational flexibility
  • + Zero debt and minimal capital requirements reduce refinancing risk and preserve strategic options
  • + Operating losses improving 33.1% year-over-year, suggesting operational discipline or progress toward clinical milestones
  • + Strong stockholders equity of $70.1M relative to asset base indicates clean balance sheet
ChatGPT
  • + Strong liquidity with 11.5x current ratio and ~$72M cash
  • + Debt-free balance sheet; minimal fixed obligations
  • + YoY improvement in net loss and negligible capex

KZR Stock Risks: Kezar Life Sciences, Inc. Investment Risks

Claude
  • ! Pre-revenue status with zero commercial traction creates binary outcome dependency on unproven pipeline
  • ! Annual cash burn of $51.8M against reserves yields only ~16 months runway, requiring near-term capital raise
  • ! Existential clinical and regulatory risk - all enterprise value depends on FDA approvals for experimental drugs
  • ! Shareholder dilution likely from future equity financing rounds needed before profitability
  • ! No disclosed insider buying activity in 90 days, suggesting limited management conviction at current burn trajectory
ChatGPT
  • ! No revenue and persistent large operating losses
  • ! Cash runway likely under two years, implying financing/dilution risk
  • ! Negative ROE/ROA and interest coverage reflect weak profitability trajectory

Key Metrics to Watch

Claude
  • * Quarterly cash burn trend and updated runway - early indicator of financing urgency
  • * Clinical trial enrollment, efficacy data releases, and FDA milestone announcements for pipeline programs
  • * Partnership announcements or licensing deals indicating external validation of asset value
ChatGPT
  • * Operating cash flow (burn rate)
  • * Cash & equivalents (runway)

Kezar Life Sciences, Inc. (KZR) Financial Metrics & Key Ratios

Revenue
$0.0
Net Income
$-56.0M
EPS (Diluted)
$-7.66
Free Cash Flow
$-51.8M
Total Assets
$76.6M
Cash Position
$71.9M

💡 AI Analyst Insight

Strong liquidity with a 11.52x current ratio provides a solid financial cushion.

KZR Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin N/A
Net Margin N/A
ROE -80.0%
ROA -73.1%
FCF Margin N/A

KZR vs Healthcare Sector: How Kezar Life Sciences, Inc. Compares

How Kezar Life Sciences, Inc. compares to Healthcare sector averages

Net Margin
KZR 0.0%
vs
Sector Avg 12.0%
KZR Sector
ROE
KZR -80.0%
vs
Sector Avg 15.0%
KZR Sector
Current Ratio
KZR 11.5x
vs
Sector Avg 2.0x
KZR Sector
Debt/Equity
KZR 0.0x
vs
Sector Avg 0.6x
KZR Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Kezar Life Sciences, Inc. Stock Overvalued? KZR Valuation Analysis 2026

Based on fundamental analysis, Kezar Life Sciences, Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-80.0%
Sector avg: 15%
Net Profit Margin
N/A
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Kezar Life Sciences, Inc. Balance Sheet: KZR Debt, Cash & Liquidity

Current Ratio
11.52x
Quick Ratio
11.52x
Debt/Equity
0.00x
Debt/Assets
8.6%
Interest Coverage
-49.09x
Long-term Debt
$0.0

KZR Revenue & Earnings Growth: 5-Year Financial Trend

KZR 5-year financial data: Year 2023: Revenue $7.0M, Net Income -$54.6M, EPS $-1.04. Year 2024: Revenue $7.0M, Net Income -$68.2M, EPS $-10.13. Year 2025: Revenue $7.0M, Net Income -$101.9M, EPS $-14.04.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Kezar Life Sciences, Inc.'s revenue has remained relatively flat over the 5-year period, with a 0% decline. The most recent EPS of $-14.04 indicates the company is currently unprofitable.

KZR Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
N/A
Free cash flow / Revenue

KZR Quarterly Earnings & Performance

Quarterly financial performance data for Kezar Life Sciences, Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2024 N/A -$20.3M $-2.78
Q3 2023 N/A -$16.0M $-0.25

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Kezar Life Sciences, Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$51.8M
Cash generated from operations
Capital Expenditures
$8.0K
Investment in assets
Dividends
None
No dividend program

KZR SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Kezar Life Sciences, Inc. (CIK: 0001645666)

📋 Recent SEC Filings

Date Form Document Action
Apr 3, 2026 8-K kzr-20260401.htm View →
Mar 30, 2026 8-K d106892d8k.htm View →
Mar 27, 2026 10-K kzr-20251231.htm View →
Mar 12, 2026 8-K kzr-20260306.htm View →
Nov 12, 2025 10-Q kzr-20250930.htm View →

Frequently Asked Questions about KZR

What is the AI rating for KZR?

Kezar Life Sciences, Inc. (KZR) has a Combined AI Rating of SELL from Claude (HOLD) and ChatGPT (SELL) with 70% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are KZR's key strengths?

Claude: Exceptional liquidity with $71.9M cash reserve against only $6.6M liabilities, providing substantial operational flexibility. Zero debt and minimal capital requirements reduce refinancing risk and preserve strategic options. ChatGPT: Strong liquidity with 11.5x current ratio and ~$72M cash. Debt-free balance sheet; minimal fixed obligations.

What are the risks of investing in KZR?

Claude: Pre-revenue status with zero commercial traction creates binary outcome dependency on unproven pipeline. Annual cash burn of $51.8M against reserves yields only ~16 months runway, requiring near-term capital raise. ChatGPT: No revenue and persistent large operating losses. Cash runway likely under two years, implying financing/dilution risk.

What is KZR's revenue and growth?

Kezar Life Sciences, Inc. reported revenue of $0.0.

Does KZR pay dividends?

Kezar Life Sciences, Inc. does not currently pay dividends.

Where can I find KZR SEC filings?

Official SEC filings for Kezar Life Sciences, Inc. (CIK: 0001645666) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is KZR's EPS?

Kezar Life Sciences, Inc. has a diluted EPS of $-7.66.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is KZR a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Kezar Life Sciences, Inc. has a SELL rating with 70% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is KZR stock overvalued or undervalued?

Valuation metrics for KZR: ROE of -80.0% (sector avg: 15%), net margin of N/A (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy KZR stock in 2026?

Our dual AI analysis gives Kezar Life Sciences, Inc. a combined SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is KZR's free cash flow?

Kezar Life Sciences, Inc.'s operating cash flow is $-51.8M, with capital expenditures of $8.0K.

How does KZR compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin N/A (avg: 12%), ROE -80.0% (avg: 15%), current ratio 11.52 (avg: 2).

Top Rated Stocks
NSSC 92% MLI 92% MELI 92% MDXG 92% MANH 92% INVA 92% GGG 92% GCT 92% FTNT 92% FSLR 92%
Sector: All Healthcare Stocks →
Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Apr 12, 2026 | Data as of: 2025-12-31 | Powered by Claude AI