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Heron Therapeutics, Inc.. /DE/ (HRTX) Stock Fundamental Analysis & AI Rating 2026

HRTX Nasdaq Pharmaceutical Preparations DE CIK: 0000818033
Recently Updated • Analysis: Apr 11, 2026 • SEC Data: 2025-12-31
Combined AI Rating
SELL
76% Confidence
AGREEMENT
STRONG SELL
87% Conf
SELL
66% Conf

📊 HRTX Key Takeaways

Revenue: $154.9M
Net Margin: -13.0%
Free Cash Flow: $-27.9M
Current Ratio: 2.48x
Debt/Equity: 0.00x
EPS: $-0.12
AI Rating: STRONG SELL with 87% confidence
Heron Therapeutics, Inc.. /DE/ (HRTX) receives a SELL rating with 76% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $154.9M, net profit margin of -13.0%, and return on equity (ROE) of -140.9%, Heron Therapeutics, Inc.. /DE/ demonstrates mixed fundamentals in the Healthcare sector. Below is our complete HRTX stock analysis for 2026.

Is Heron Therapeutics, Inc.. /DE/ (HRTX) a Good Investment?

Claude

Heron Therapeutics exhibits a critical mismatch between revenue quality and expense structure, with strong 73.3% gross margins undermined by severe operating losses of -$2.5M and net losses of -$20.2M. The company is burning cash at -$27.6M annually with only ~12 months of financial runway at current burn rates, while maintaining a dangerously thin equity cushion of $14.3M against $241.5M in liabilities, creating acute solvency risk.

ChatGPT

High 73% gross margin and modest 7% revenue growth show product traction and improving operating leverage near breakeven. Yet persistent net losses, negative free cash flow, and a razor‑thin equity base create elevated financing/dilution risk unless operating cash flow turns sustainably positive soon.

Why Buy Heron Therapeutics, Inc.. /DE/ Stock? HRTX Key Strengths

Claude
  • + Strong gross margin of 73.3% demonstrates pricing power and product quality
  • + Positive revenue growth of 7.4% YoY shows market traction and commercial capability
  • + No long-term debt provides financial flexibility and eliminates refinancing risk
ChatGPT
  • + Strong gross margin indicating pricing power
  • + Operating margin near breakeven suggests improving cost control
  • + Solid near-term liquidity with a 2.5x current ratio

HRTX Stock Risks: Heron Therapeutics, Inc.. /DE/ Investment Risks

Claude
  • ! Negative operating cash flow of -$27.6M annually is unsustainable with only ~12 months cash runway remaining
  • ! Dangerously thin stockholders equity of $14.3M vs $241.5M liabilities creates extreme solvency risk and limits strategic options
  • ! Deeply unprofitable with net margin of -13.0% despite revenue generation, indicating uncontrollable cost structure
ChatGPT
  • ! Negative free cash flow and OCF imply ongoing cash burn
  • ! Very thin equity and severe negative ROE highlight balance-sheet fragility
  • ! Negative interest coverage and high liabilities relative to assets raise solvency risk

Key Metrics to Watch

Claude
  • * Operating cash flow trend and path to positive OCF
  • * Cash balance depletion rate and runway extension
  • * Operating expense reduction and path to operating profitability
ChatGPT
  • * Operating cash flow and cash runway (cash/FCF)
  • * Operating margin progression toward sustained profitability

Heron Therapeutics, Inc.. /DE/ (HRTX) Financial Metrics & Key Ratios

Revenue
$154.9M
Net Income
$-20.2M
EPS (Diluted)
$-0.12
Free Cash Flow
$-27.9M
Total Assets
$255.9M
Cash Position
$28.6M

💡 AI Analyst Insight

Strong liquidity with a 2.48x current ratio provides a solid financial cushion.

HRTX Profit Margin, ROE & Profitability Analysis

Gross Margin 73.3%
Operating Margin -1.6%
Net Margin -13.0%
ROE -140.9%
ROA -7.9%
FCF Margin -18.0%

HRTX vs Healthcare Sector: How Heron Therapeutics, Inc.. /DE/ Compares

How Heron Therapeutics, Inc.. /DE/ compares to Healthcare sector averages

Net Margin
HRTX -13.0%
vs
Sector Avg 12.0%
HRTX Sector
ROE
HRTX -140.9%
vs
Sector Avg 15.0%
HRTX Sector
Current Ratio
HRTX 2.5x
vs
Sector Avg 2.0x
HRTX Sector
Debt/Equity
HRTX 0.0x
vs
Sector Avg 0.6x
HRTX Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Heron Therapeutics, Inc.. /DE/ Stock Overvalued? HRTX Valuation Analysis 2026

Based on fundamental analysis, Heron Therapeutics, Inc.. /DE/ has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-140.9%
Sector avg: 15%
Net Profit Margin
-13.0%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Heron Therapeutics, Inc.. /DE/ Balance Sheet: HRTX Debt, Cash & Liquidity

Current Ratio
2.48x
Quick Ratio
1.51x
Debt/Equity
0.00x
Debt/Assets
94.4%
Interest Coverage
-0.66x
Long-term Debt
N/A

HRTX Revenue & Earnings Growth: 5-Year Financial Trend

HRTX 5-year financial data: Year 2021: Revenue $146.0M, Net Income -$204.7M, EPS N/A. Year 2022: Revenue $107.7M, Net Income -$220.7M, EPS $-2.24. Year 2023: Revenue $127.0M, Net Income -$182.0M, EPS $-1.67. Year 2024: Revenue $144.3M, Net Income -$182.0M, EPS $-1.67. Year 2025: Revenue $154.9M, Net Income -$110.6M, EPS $-0.80.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Heron Therapeutics, Inc.. /DE/'s revenue has shown modest growth of 6% over the 5-year period. The most recent EPS of $-0.80 indicates the company is currently unprofitable.

HRTX Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-18.0%
Free cash flow / Revenue

HRTX Quarterly Earnings & Performance

Quarterly financial performance data for Heron Therapeutics, Inc.. /DE/ including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 $32.8M -$2.4M $-0.03
Q2 2025 $36.0M $254.0K $0.00
Q1 2025 $34.7M $2.6M $0.01
Q3 2024 $31.4M -$3.2M $-0.03
Q2 2024 $31.8M -$3.2M $-0.06
Q1 2024 $29.6M -$3.2M $-0.02
Q3 2023 $26.6M -$25.0M $-0.17
Q2 2023 $27.6M -$32.8M $-0.35

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Heron Therapeutics, Inc.. /DE/ Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$27.6M
Cash generated from operations
Capital Expenditures
$317.0K
Investment in assets
Dividends
None
No dividend program

HRTX SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Heron Therapeutics, Inc.. /DE/ (CIK: 0000818033)

📋 Recent SEC Filings

Date Form Document Action
Apr 6, 2026 4 xslF345X06/ownership.xml View →
Apr 6, 2026 8-K hrtx-20260403.htm View →
Feb 26, 2026 10-K hrtx-20251231.htm View →
Feb 26, 2026 8-K hrtx-20260226.htm View →
Feb 3, 2026 4 xslF345X05/ownership.xml View →

Frequently Asked Questions about HRTX

What is the AI rating for HRTX?

Heron Therapeutics, Inc.. /DE/ (HRTX) has a Combined AI Rating of SELL from Claude (STRONG SELL) and ChatGPT (SELL) with 76% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are HRTX's key strengths?

Claude: Strong gross margin of 73.3% demonstrates pricing power and product quality. Positive revenue growth of 7.4% YoY shows market traction and commercial capability. ChatGPT: Strong gross margin indicating pricing power. Operating margin near breakeven suggests improving cost control.

What are the risks of investing in HRTX?

Claude: Negative operating cash flow of -$27.6M annually is unsustainable with only ~12 months cash runway remaining. Dangerously thin stockholders equity of $14.3M vs $241.5M liabilities creates extreme solvency risk and limits strategic options. ChatGPT: Negative free cash flow and OCF imply ongoing cash burn. Very thin equity and severe negative ROE highlight balance-sheet fragility.

What is HRTX's revenue and growth?

Heron Therapeutics, Inc.. /DE/ reported revenue of $154.9M.

Does HRTX pay dividends?

Heron Therapeutics, Inc.. /DE/ does not currently pay dividends.

Where can I find HRTX SEC filings?

Official SEC filings for Heron Therapeutics, Inc.. /DE/ (CIK: 0000818033) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is HRTX's EPS?

Heron Therapeutics, Inc.. /DE/ has a diluted EPS of $-0.12.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is HRTX a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Heron Therapeutics, Inc.. /DE/ has a SELL rating with 76% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is HRTX stock overvalued or undervalued?

Valuation metrics for HRTX: ROE of -140.9% (sector avg: 15%), net margin of -13.0% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy HRTX stock in 2026?

Our dual AI analysis gives Heron Therapeutics, Inc.. /DE/ a combined SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is HRTX's free cash flow?

Heron Therapeutics, Inc.. /DE/'s operating cash flow is $-27.6M, with capital expenditures of $317.0K. FCF margin is -18.0%.

How does HRTX compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -13.0% (avg: 12%), ROE -140.9% (avg: 15%), current ratio 2.48 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Apr 11, 2026 | Data as of: 2025-12-31 | Powered by Claude AI