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Equillium, Inc. (EQ) Stock Fundamental Analysis & AI Rating 2026

EQ Nasdaq Pharmaceutical Preparations DE CIK: 0001746466
Updated This Month • Analysis: Mar 24, 2026 • SEC Data: 2025-09-30
Combined AI Rating
SELL
81% Confidence
STRONG AGREEMENT
SELL
85% Conf
SELL
77% Conf

📊 EQ Key Takeaways

Revenue: $41.1M
Net Margin: -45.3%
Free Cash Flow: $-19.6M
Current Ratio: 10.85x
Debt/Equity: 0.25x
EPS: $-0.41
AI Rating: SELL with 85% confidence
Equillium, Inc. (EQ) receives a SELL rating with 81% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $41.1M, net profit margin of -45.3%, and return on equity (ROE) of -60.2%, Equillium, Inc. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete EQ stock analysis for 2026.

Is Equillium, Inc. (EQ) a Good Investment?

Claude

Equillium is a pre-commercial stage pharmaceutical company with severe cash burn, negative profitability across all metrics, and deteriorating operational efficiency despite modest revenue growth. While the company maintains strong liquidity with $33.1M cash and a fortress balance sheet, current burn rate of $19.6M annually and negative margins of -45%+ indicate the company is years away from sustainable operations without significant clinical success or capital raises.

ChatGPT

Equillium shows adequate near-term financial stability, with cash of $33.12M, very low balance-sheet strain, and strong current liquidity at 10.85x. However, the business remains deeply unprofitable, with negative operating margin, negative free cash flow, and weak returns on equity and assets, which makes the recent revenue growth low quality unless it converts into sustained operating leverage. Fundamentally, the company looks more like a cash-funded development-stage operation than a self-sustaining enterprise.

Why Buy Equillium, Inc. Stock? EQ Key Strengths

Claude
  • + Strong liquidity position with $33.1M cash against only $3.6M liabilities
  • + Low leverage with 0.25x debt-to-equity ratio providing financial flexibility
  • + Revenue growth of 13.9% YoY showing some commercial traction despite pre-profitability stage
  • + Improving EPS trend with 39.5% YoY improvement in diluted EPS loss
ChatGPT
  • + Strong liquidity, with cash representing most of total assets and current and quick ratios both at 10.85x
  • + Low reported leverage relative to equity, with debt/equity of 0.25x and limited total liabilities
  • + Revenue increased 13.9% year over year and diluted EPS improved, indicating some operating progress

EQ Stock Risks: Equillium, Inc. Investment Risks

Claude
  • ! Massive negative cash burn of $19.6M annually with no path to profitability visible
  • ! Net margin of -45.3% and operating margin of -47.9% indicate losses exceed revenues
  • ! Cash runway of approximately 1.7 years at current burn rate without additional revenue growth
  • ! Pharmaceutical sector execution risk with clinical pipeline success critical to viability
  • ! Negative ROE of -60.2% and ROA of -54.0% showing severe capital inefficiency
  • ! Operating expenses far exceed revenue, requiring major operational restructuring or breakthrough product success
ChatGPT
  • ! Profitability remains very weak, with operating margin of -47.9% and net margin of -45.3%
  • ! Free cash flow is deeply negative at -$19.62M, implying continued cash burn and possible future financing needs
  • ! Returns on capital are poor, with ROE of -60.2% and ROA of -54.0%, suggesting the asset base is not generating economic value

Key Metrics to Watch

Claude
  • * Operating cash flow trend and monthly burn rate trajectory
  • * Revenue growth acceleration and product commercialization progress
  • * Operating expense management and path to breakeven timeline
  • * Clinical trial results and regulatory milestones for pipeline programs
  • * Cash runway and timing/terms of any future capital raises
ChatGPT
  • * Quarterly operating cash burn and cash runway
  • * Whether revenue growth meaningfully narrows operating and net losses

Equillium, Inc. (EQ) Financial Metrics & Key Ratios

Revenue
$41.1M
Net Income
$-18.6M
EPS (Diluted)
$-0.41
Free Cash Flow
$-19.6M
Total Assets
$34.5M
Cash Position
$33.1M

💡 AI Analyst Insight

Strong liquidity with a 10.85x current ratio provides a solid financial cushion.

EQ Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin -47.9%
Net Margin -45.3%
ROE -60.2%
ROA -54.0%
FCF Margin -47.7%

EQ vs Healthcare Sector: How Equillium, Inc. Compares

How Equillium, Inc. compares to Healthcare sector averages

Net Margin
EQ -45.3%
vs
Sector Avg 12.0%
EQ Sector
ROE
EQ -60.2%
vs
Sector Avg 15.0%
EQ Sector
Current Ratio
EQ 10.9x
vs
Sector Avg 2.0x
EQ Sector
Debt/Equity
EQ 0.2x
vs
Sector Avg 0.6x
EQ Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Equillium, Inc. Stock Overvalued? EQ Valuation Analysis 2026

Based on fundamental analysis, Equillium, Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-60.2%
Sector avg: 15%
Net Profit Margin
-45.3%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.25x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Equillium, Inc. Balance Sheet: EQ Debt, Cash & Liquidity

Current Ratio
10.85x
Quick Ratio
10.85x
Debt/Equity
0.25x
Debt/Assets
10.3%
Interest Coverage
-40.07x
Long-term Debt
$7.6M

EQ Revenue & Earnings Growth: 5-Year Financial Trend

EQ 5-year financial data: Year 2022: Revenue $15.8M, Net Income -$39.1M, EPS $-1.36. Year 2023: Revenue $36.1M, Net Income -$62.4M, EPS $-1.85. Year 2024: Revenue $41.1M, Net Income -$13.3M, EPS $-0.38. Year 2025: Revenue $41.1M, Net Income -$8.1M, EPS $-0.23.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Equillium, Inc.'s revenue has grown significantly by 161% over the 5-year period, indicating strong business expansion. The most recent EPS of $-0.23 indicates the company is currently unprofitable.

EQ Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-47.7%
Free cash flow / Revenue

EQ Quarterly Earnings & Performance

Quarterly financial performance data for Equillium, Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 $12.2M -$7.0K $0.00
Q2 2025 $13.9M $468.0K $0.01
Q1 2025 $10.7M -$2.7M $-0.08
Q3 2024 $8.9M -$7.0K $0.00
Q2 2024 $9.1M $468.0K $0.01
Q1 2024 $8.9M -$2.7M $-0.08
Q3 2023 $8.9M -$3.3M $-0.11
Q2 2023 $9.1M -$3.3M $-0.10

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Equillium, Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$19.6M
Cash generated from operations
Stock Buybacks
$260.0K
Shares repurchased (TTM)
Capital Expenditures
$4.0K
Investment in assets
Dividends
None
No dividend program

EQ SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Equillium, Inc. (CIK: 0001746466)

📋 Recent SEC Filings

Date Form Document Action
Apr 15, 2026 DEF 14A eq-20260414.htm View →
Mar 25, 2026 10-K eq-20251231.htm View →
Mar 25, 2026 8-K eq-20260325.htm View →
Mar 16, 2026 4 xslF345X05/form4-03162026_100332.xml View →
Mar 13, 2026 8-K d125584d8k.htm View →

Frequently Asked Questions about EQ

What is the AI rating for EQ?

Equillium, Inc. (EQ) has a Combined AI Rating of SELL from Claude (SELL) and ChatGPT (SELL) with 81% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are EQ's key strengths?

Claude: Strong liquidity position with $33.1M cash against only $3.6M liabilities. Low leverage with 0.25x debt-to-equity ratio providing financial flexibility. ChatGPT: Strong liquidity, with cash representing most of total assets and current and quick ratios both at 10.85x. Low reported leverage relative to equity, with debt/equity of 0.25x and limited total liabilities.

What are the risks of investing in EQ?

Claude: Massive negative cash burn of $19.6M annually with no path to profitability visible. Net margin of -45.3% and operating margin of -47.9% indicate losses exceed revenues. ChatGPT: Profitability remains very weak, with operating margin of -47.9% and net margin of -45.3%. Free cash flow is deeply negative at -$19.62M, implying continued cash burn and possible future financing needs.

What is EQ's revenue and growth?

Equillium, Inc. reported revenue of $41.1M.

Does EQ pay dividends?

Equillium, Inc. does not currently pay dividends.

Where can I find EQ SEC filings?

Official SEC filings for Equillium, Inc. (CIK: 0001746466) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is EQ's EPS?

Equillium, Inc. has a diluted EPS of $-0.41.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is EQ a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Equillium, Inc. has a SELL rating with 81% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is EQ stock overvalued or undervalued?

Valuation metrics for EQ: ROE of -60.2% (sector avg: 15%), net margin of -45.3% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy EQ stock in 2026?

Our dual AI analysis gives Equillium, Inc. a combined SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is EQ's free cash flow?

Equillium, Inc.'s operating cash flow is $-19.6M, with capital expenditures of $4.0K. FCF margin is -47.7%.

How does EQ compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -45.3% (avg: 12%), ROE -60.2% (avg: 15%), current ratio 10.85 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Mar 24, 2026 | Data as of: 2025-09-30 | Powered by Claude AI