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Ensysce Biosciences, Inc. (ENSCW) Stock Fundamental Analysis & AI Rating 2026

ENSCW Nasdaq Pharmaceutical Preparations DE CIK: 0001716947
Updated This Month • Analysis: Mar 24, 2026 • SEC Data: 2025-09-30
Combined AI Rating
STRONG SELL
94% Confidence
STRONG AGREEMENT
STRONG SELL
95% Conf
STRONG SELL
92% Conf

📊 ENSCW Key Takeaways

Revenue: $3.2M
Net Margin: -232.6%
Free Cash Flow: $-6.4M
Current Ratio: 1.27x
Debt/Equity: 0.00x
EPS: $-3.42
AI Rating: STRONG SELL with 95% confidence
Ensysce Biosciences, Inc. (ENSCW) receives a STRONG SELL rating with 94% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $3.2M, net profit margin of -232.6%, and return on equity (ROE) of -615.6%, Ensysce Biosciences, Inc. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete ENSCW stock analysis for 2026.

Is Ensysce Biosciences, Inc. (ENSCW) a Good Investment?

Claude

Ensysce Biosciences is a severely distressed pharmaceutical company with minimal revenue ($3.2M), massive operating losses (-$7.5M), and a -232.6% net margin indicating the business is burning cash at an unsustainable rate. With negative free cash flow of -$6.4M and only $1.7M in cash reserves against $2.3M in liabilities, the company faces imminent liquidity constraints and potential insolvency without significant capital infusion or operational turnaround.

ChatGPT

Ensysce Biosciences shows extremely weak fundamentals, with minimal revenue relative to its cost base, deeply negative operating and net margins, and persistent cash burn that materially exceeds its revenue. While the balance sheet is not debt-heavy, the company's small cash position and low equity base suggest continued dependence on external financing unless operating losses narrow substantially.

Why Buy Ensysce Biosciences, Inc. Stock? ENSCW Key Strengths

Claude
  • + Positive current ratio of 1.27x provides short-term liquidity cushion
  • + No long-term debt reduces leverage risk and balance sheet complexity
  • + Cash position of $1.7M provides runway for near-term operations
ChatGPT
  • + Debt-free capital structure reduces balance-sheet leverage risk
  • + Current and quick ratios above 1.0 indicate near-term obligations are currently covered
  • + Reported revenue is stable year over year, providing at least some non-zero top-line base

ENSCW Stock Risks: Ensysce Biosciences, Inc. Investment Risks

Claude
  • ! Revenue of $3.2M is insufficient to cover operating expenses of $10.7M, indicating fundamental business model failure
  • ! Negative free cash flow of -$6.4M will deplete $1.7M cash reserve in approximately 3 months at current burn rate
  • ! Operating margin of -234.2% and net margin of -232.6% demonstrate the company is not close to profitability
  • ! Zero insider purchases in last 90 days suggests lack of management confidence in the business
  • ! ROE of -615.6% and ROA of -233.0% indicate severe shareholder value destruction
ChatGPT
  • ! Operating and net losses are far larger than revenue, indicating an unsustainable business model at current scale
  • ! Negative operating cash flow and free cash flow imply limited cash runway relative to annual burn
  • ! Very low equity base and deeply negative ROE increase dilution and financing risk

Key Metrics to Watch

Claude
  • * Monthly cash burn rate and months of cash runway remaining
  • * Revenue growth trajectory and path to profitability
  • * Insider buying activity as indicator of management confidence
ChatGPT
  • * Quarterly operating cash burn relative to cash and equivalents
  • * Progress in scaling recurring revenue and reducing operating loss

Ensysce Biosciences, Inc. (ENSCW) Financial Metrics & Key Ratios

Revenue
$3.2M
Net Income
$-7.4M
EPS (Diluted)
$-3.42
Free Cash Flow
$-6.4M
Total Assets
$3.2M
Cash Position
$1.7M

💡 AI Analyst Insight

Ensysce Biosciences, Inc. presents a mixed fundamental picture. Review the detailed metrics above to form your own investment thesis.

ENSCW Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin -234.2%
Net Margin -232.6%
ROE -615.6%
ROA -233.0%
FCF Margin -201.1%

ENSCW vs Healthcare Sector: How Ensysce Biosciences, Inc. Compares

How Ensysce Biosciences, Inc. compares to Healthcare sector averages

Net Margin
ENSCW -232.6%
vs
Sector Avg 12.0%
ENSCW Sector
ROE
ENSCW -615.6%
vs
Sector Avg 15.0%
ENSCW Sector
Current Ratio
ENSCW 1.3x
vs
Sector Avg 2.0x
ENSCW Sector
Debt/Equity
ENSCW 0.0x
vs
Sector Avg 0.6x
ENSCW Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Ensysce Biosciences, Inc. Stock Overvalued? ENSCW Valuation Analysis 2026

Based on fundamental analysis, Ensysce Biosciences, Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-615.6%
Sector avg: 15%
Net Profit Margin
-232.6%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Ensysce Biosciences, Inc. Balance Sheet: ENSCW Debt, Cash & Liquidity

Current Ratio
1.27x
Quick Ratio
1.27x
Debt/Equity
0.00x
Debt/Assets
72.5%
Interest Coverage
-1,811.35x
Long-term Debt
N/A

ENSCW Revenue & Earnings Growth: 5-Year Financial Trend

ENSCW 5-year financial data: Year 2022: Revenue $3.5M, Net Income -$29.1M, EPS N/A. Year 2023: Revenue $2.5M, Net Income -$24.2M, EPS $-139.42. Year 2024: Revenue $5.2M, Net Income -$10.6M, EPS $-70.40. Year 2025: Revenue $5.2M, Net Income -$8.0M, EPS $-11.45.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Ensysce Biosciences, Inc.'s revenue has grown significantly by 48% over the 5-year period, indicating strong business expansion. The most recent EPS of $-11.45 indicates the company is currently unprofitable.

ENSCW Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-201.1%
Free cash flow / Revenue

ENSCW Quarterly Earnings & Performance

Quarterly financial performance data for Ensysce Biosciences, Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 $493.1K $661.8K $1.00
Q2 2025 $181.8K -$1.7M $-0.79
Q1 2025 $305.7K -$1.9M $-1.39
Q3 2024 $435.4K $661.8K $0.07
Q2 2024 $181.8K -$2.0M $-0.22
Q1 2024 $305.7K -$2.2M $-0.55
Q3 2023 $279.4K -$2.7M $-0.87
Q2 2023 $207.5K -$2.2M $-0.98

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Ensysce Biosciences, Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$6.3M
Cash generated from operations
Stock Buybacks
$136.3M
Shares repurchased (TTM)
Capital Expenditures
$123.6K
Investment in assets
Dividends
None
No dividend program

ENSCW SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Ensysce Biosciences, Inc. (CIK: 0001716947)

📋 Recent SEC Filings

Date Form Document Action
Apr 8, 2026 8-K form8-k.htm View →
Apr 3, 2026 8-K form8-k.htm View →
Mar 30, 2026 10-K form10-k.htm View →
Mar 30, 2026 8-K form8-k.htm View →
Mar 30, 2026 8-K form8-k.htm View →

Frequently Asked Questions about ENSCW

What is the AI rating for ENSCW?

Ensysce Biosciences, Inc. (ENSCW) has a Combined AI Rating of STRONG SELL from Claude (STRONG SELL) and ChatGPT (STRONG SELL) with 94% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are ENSCW's key strengths?

Claude: Positive current ratio of 1.27x provides short-term liquidity cushion. No long-term debt reduces leverage risk and balance sheet complexity. ChatGPT: Debt-free capital structure reduces balance-sheet leverage risk. Current and quick ratios above 1.0 indicate near-term obligations are currently covered.

What are the risks of investing in ENSCW?

Claude: Revenue of $3.2M is insufficient to cover operating expenses of $10.7M, indicating fundamental business model failure. Negative free cash flow of -$6.4M will deplete $1.7M cash reserve in approximately 3 months at current burn rate. ChatGPT: Operating and net losses are far larger than revenue, indicating an unsustainable business model at current scale. Negative operating cash flow and free cash flow imply limited cash runway relative to annual burn.

What is ENSCW's revenue and growth?

Ensysce Biosciences, Inc. reported revenue of $3.2M.

Does ENSCW pay dividends?

Ensysce Biosciences, Inc. does not currently pay dividends.

Where can I find ENSCW SEC filings?

Official SEC filings for Ensysce Biosciences, Inc. (CIK: 0001716947) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is ENSCW's EPS?

Ensysce Biosciences, Inc. has a diluted EPS of $-3.42.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is ENSCW a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Ensysce Biosciences, Inc. has a STRONG SELL rating with 94% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is ENSCW stock overvalued or undervalued?

Valuation metrics for ENSCW: ROE of -615.6% (sector avg: 15%), net margin of -232.6% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy ENSCW stock in 2026?

Our dual AI analysis gives Ensysce Biosciences, Inc. a combined STRONG SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is ENSCW's free cash flow?

Ensysce Biosciences, Inc.'s operating cash flow is $-6.3M, with capital expenditures of $123.6K. FCF margin is -201.1%.

How does ENSCW compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -232.6% (avg: 12%), ROE -615.6% (avg: 15%), current ratio 1.27 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Mar 24, 2026 | Data as of: 2025-09-30 | Powered by Claude AI