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Dianthus Therapeutics, Inc. /DE/ (DNTH) Stock Fundamental Analysis & AI Rating 2026

DNTH Nasdaq Pharmaceutical Preparations DE CIK: 0001690585
Updated This Month • Analysis: Mar 23, 2026 • SEC Data: 2025-12-31
Combined AI Rating
SELL
85% Confidence
AGREEMENT
STRONG SELL
92% Conf
SELL
78% Conf

📊 DNTH Key Takeaways

Revenue: $2.0M
Net Margin: -7,973.3%
Free Cash Flow: $-129.3M
Current Ratio: 13.32x
Debt/Equity: 0.00x
EPS: $-4.20
AI Rating: STRONG SELL with 92% confidence
Dianthus Therapeutics, Inc. /DE/ (DNTH) receives a SELL rating with 85% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $2.0M, net profit margin of -7,973.3%, and return on equity (ROE) of -32.9%, Dianthus Therapeutics, Inc. /DE/ demonstrates mixed fundamentals in the Healthcare sector. Below is our complete DNTH stock analysis for 2026.

Is Dianthus Therapeutics, Inc. /DE/ (DNTH) a Good Investment?

Claude

Dianthus Therapeutics is a pre-revenue biotech company burning significant cash with minimal revenue generation ($2M annually) and operating losses of $177.9M, indicating an early-stage development company far from profitability. The company's -$129.1M operating cash flow and -$129.3M free cash flow demonstrate unsustainable cash burn rates despite holding $51.1M in cash, providing only ~5 months of runway at current burn rates. Fundamental profitability and growth metrics are severely negative, with no clear path to revenue generation evident.

ChatGPT

Dianthus Therapeutics shows very weak current fundamentals, with minimal revenue, deeply negative operating and net margins, and heavy ongoing cash burn. The balance sheet is a clear strength because the company has substantial equity, strong liquidity, and no meaningful leverage, but the business remains dependent on converting R&D spending into future commercial progress.

Why Buy Dianthus Therapeutics, Inc. /DE/ Stock? DNTH Key Strengths

Claude
  • + Strong balance sheet composition with $493.4M stockholders' equity and minimal debt (0.00x debt/equity ratio)
  • + Adequate short-term liquidity with 13.32x current ratio and $51.1M cash position
  • + Elevated insider activity (9 Form 4 filings in 90 days) may indicate management confidence in pipeline
ChatGPT
  • + Very strong liquidity with current and quick ratios of 13.32x
  • + Large equity base and low liabilities support balance-sheet resilience
  • + No meaningful long-term debt reduces financial distress risk

DNTH Stock Risks: Dianthus Therapeutics, Inc. /DE/ Investment Risks

Claude
  • ! Severe cash burn of $129.1M annually with only ~5 months of cash runway remaining
  • ! Negligible revenue ($2M) relative to operating expenses indicates company is far from commercialization
  • ! Extreme negative operating margins (-8739.3%) and net margins (-7973.3%) reflect pre-commercial stage with no near-term profitability path
  • ! Negative free cash flow of -$129.3M indicates company is consuming capital at unsustainable rates
ChatGPT
  • ! Extremely weak profitability, including operating margin of -8739.3% and net margin of -7973.3%
  • ! Large negative operating cash flow and free cash flow indicate sustained cash burn
  • ! Revenue base is negligible, so growth quality and business model durability remain unproven

Key Metrics to Watch

Claude
  • * Monthly cash burn rate and runway calculation
  • * Clinical trial progress and pipeline advancement milestones
  • * Revenue growth trajectory and any progress toward commercialization
  • * Changes in stockholders' equity and cash position quarter-over-quarter
ChatGPT
  • * Quarterly operating cash burn relative to cash and equivalents
  • * Meaningful revenue growth and improvement in operating loss

Dianthus Therapeutics, Inc. /DE/ (DNTH) Financial Metrics & Key Ratios

Revenue
$2.0M
Net Income
$-162.3M
EPS (Diluted)
$-4.20
Free Cash Flow
$-129.3M
Total Assets
$530.9M
Cash Position
$51.1M

💡 AI Analyst Insight

Strong liquidity with a 13.32x current ratio provides a solid financial cushion.

DNTH Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin -8,739.3%
Net Margin -7,973.3%
ROE -32.9%
ROA -30.6%
FCF Margin -6,350.9%

DNTH vs Healthcare Sector: How Dianthus Therapeutics, Inc. /DE/ Compares

How Dianthus Therapeutics, Inc. /DE/ compares to Healthcare sector averages

Net Margin
DNTH -7,973.3%
vs
Sector Avg 12.0%
DNTH Sector
ROE
DNTH -32.9%
vs
Sector Avg 15.0%
DNTH Sector
Current Ratio
DNTH 13.3x
vs
Sector Avg 2.0x
DNTH Sector
Debt/Equity
DNTH 0.0x
vs
Sector Avg 0.6x
DNTH Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Dianthus Therapeutics, Inc. /DE/ Stock Overvalued? DNTH Valuation Analysis 2026

Based on fundamental analysis, Dianthus Therapeutics, Inc. /DE/ has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-32.9%
Sector avg: 15%
Net Profit Margin
-7,973.3%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Dianthus Therapeutics, Inc. /DE/ Balance Sheet: DNTH Debt, Cash & Liquidity

Current Ratio
13.32x
Quick Ratio
13.32x
Debt/Equity
0.00x
Debt/Assets
7.1%
Interest Coverage
-1,091.61x
Long-term Debt
N/A

DNTH Revenue & Earnings Growth: 5-Year Financial Trend

DNTH 5-year financial data: Year 2024: Revenue $6.2M, Net Income -$43.6M, EPS $-8.45. Year 2025: Revenue $6.2M, Net Income -$85.0M, EPS $-2.55.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Dianthus Therapeutics, Inc. /DE/'s revenue has remained relatively flat over the 5-year period, with a 0% decline. The most recent EPS of $-2.55 indicates the company is currently unprofitable.

DNTH Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-6,350.9%
Free cash flow / Revenue

DNTH Quarterly Earnings & Performance

Quarterly financial performance data for Dianthus Therapeutics, Inc. /DE/ including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 $396.0K -$13.7M $-0.74
Q2 2025 $193.0K -$13.7M $-0.51
Q1 2025 $874.0K -$13.7M $-0.54
Q3 2023 $924.0K -$4.9M $-3.78

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Dianthus Therapeutics, Inc. /DE/ Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$129.1M
Cash generated from operations
Capital Expenditures
$245.0K
Investment in assets
Dividends
None
No dividend program

DNTH SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Dianthus Therapeutics, Inc. /DE/ (CIK: 0001690585)

📋 Recent SEC Filings

Date Form Document Action
Apr 10, 2026 4 xslF345X06/ownership.xml View →
Apr 9, 2026 DEF 14A dnth-20260409.htm View →
Apr 1, 2026 4 xslF345X06/ownership.xml View →
Apr 1, 2026 4 xslF345X06/ownership.xml View →
Mar 26, 2026 4 xslF345X06/ownership.xml View →

Frequently Asked Questions about DNTH

What is the AI rating for DNTH?

Dianthus Therapeutics, Inc. /DE/ (DNTH) has a Combined AI Rating of SELL from Claude (STRONG SELL) and ChatGPT (SELL) with 85% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are DNTH's key strengths?

Claude: Strong balance sheet composition with $493.4M stockholders' equity and minimal debt (0.00x debt/equity ratio). Adequate short-term liquidity with 13.32x current ratio and $51.1M cash position. ChatGPT: Very strong liquidity with current and quick ratios of 13.32x. Large equity base and low liabilities support balance-sheet resilience.

What are the risks of investing in DNTH?

Claude: Severe cash burn of $129.1M annually with only ~5 months of cash runway remaining. Negligible revenue ($2M) relative to operating expenses indicates company is far from commercialization. ChatGPT: Extremely weak profitability, including operating margin of -8739.3% and net margin of -7973.3%. Large negative operating cash flow and free cash flow indicate sustained cash burn.

What is DNTH's revenue and growth?

Dianthus Therapeutics, Inc. /DE/ reported revenue of $2.0M.

Does DNTH pay dividends?

Dianthus Therapeutics, Inc. /DE/ does not currently pay dividends.

Where can I find DNTH SEC filings?

Official SEC filings for Dianthus Therapeutics, Inc. /DE/ (CIK: 0001690585) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is DNTH's EPS?

Dianthus Therapeutics, Inc. /DE/ has a diluted EPS of $-4.20.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is DNTH a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Dianthus Therapeutics, Inc. /DE/ has a SELL rating with 85% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is DNTH stock overvalued or undervalued?

Valuation metrics for DNTH: ROE of -32.9% (sector avg: 15%), net margin of -7,973.3% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy DNTH stock in 2026?

Our dual AI analysis gives Dianthus Therapeutics, Inc. /DE/ a combined SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is DNTH's free cash flow?

Dianthus Therapeutics, Inc. /DE/'s operating cash flow is $-129.1M, with capital expenditures of $245.0K. FCF margin is -6,350.9%.

How does DNTH compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -7,973.3% (avg: 12%), ROE -32.9% (avg: 15%), current ratio 13.32 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Mar 23, 2026 | Data as of: 2025-12-31 | Powered by Claude AI