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Cryoport, Inc. (CYRX) Stock Fundamental Analysis & AI Rating 2026

CYRX Nasdaq Pharmaceutical Preparations NV CIK: 0001124524
Updated This Month • Analysis: Mar 23, 2026 • SEC Data: 2025-12-31
Combined AI Rating
SELL
68% Confidence
AGREEMENT
HOLD
55% Conf
SELL
82% Conf

📊 CYRX Key Takeaways

Revenue: $176.2M
Net Margin: 44.4%
Free Cash Flow: $-25.0M
Current Ratio: 2.17x
Debt/Equity: 0.23x
EPS: $1.40
AI Rating: HOLD with 55% confidence
Cryoport, Inc. (CYRX) receives a SELL rating with 68% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $176.2M, net profit margin of 44.4%, and return on equity (ROE) of 15.6%, Cryoport, Inc. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete CYRX stock analysis for 2026.

Is Cryoport, Inc. (CYRX) a Good Investment?

Claude

Cryoport exhibits a paradoxical financial profile with strong profitability metrics (44.4% net margin, 15.6% ROE) but severe operational weakness (-20.9% operating margin, -$25M free cash flow). The 11.4% net income growth is driven by non-operating gains rather than core business improvement, and negative operating cash flow signals fundamental business sustainability concerns despite reported profitability.

ChatGPT

Cryoport’s balance sheet is solid, with substantial cash, good liquidity, and modest leverage, but the core business remains fundamentally weak. Revenue is flat, operating margins are deeply negative, and both operating cash flow and free cash flow are negative, which suggests the strong net income and EPS likely do not reflect durable operating performance.

Why Buy Cryoport, Inc. Stock? CYRX Key Strengths

Claude
  • + Strong net profit margin of 44.4% demonstrates pricing power and efficient cost management at bottom line
  • + Healthy balance sheet with $250.5M cash, 2.17x current ratio, and conservative 0.23x debt/equity ratio providing financial flexibility
  • + Solid gross margin of 47.1% indicates competitive products and strong demand in pharmaceutical logistics segment
ChatGPT
  • + Strong liquidity with $250.49M in cash and current ratio of 2.17x
  • + Low balance-sheet leverage with debt/equity of 0.23x
  • + Healthy gross margin of 47.1%, indicating the underlying service mix still has economic potential

CYRX Stock Risks: Cryoport, Inc. Investment Risks

Claude
  • ! Severe operating loss of $36.8M with -20.9% operating margin indicates core business is unprofitable despite net income gains
  • ! Negative free cash flow of -$25M with -$8.6M operating cash flow raises red flags about earnings quality and sustainability
  • ! Disconnect between reported net income growth and operational deterioration suggests one-time gains or accounting adjustments masking business decline
  • ! Negative interest coverage ratio of -27.5x indicates inability to service debt from operations
ChatGPT
  • ! Operating losses remain significant with a -20.9% operating margin
  • ! Cash generation is weak, with negative operating cash flow and -$25.02M free cash flow
  • ! Revenue growth is stalled, raising concerns about the quality and sustainability of earnings

Key Metrics to Watch

Claude
  • * Operating cash flow trend and path to positive FCF generation
  • * Operating income trajectory and operating margin expansion/contraction
  • * Revenue growth sustainability and gross margin stability
  • * Quality of earnings analysis to isolate operating vs non-operating income components
ChatGPT
  • * Operating margin and operating cash flow
  • * Revenue growth and free cash flow trend

Cryoport, Inc. (CYRX) Financial Metrics & Key Ratios

Revenue
$176.2M
Net Income
$78.3M
EPS (Diluted)
$1.40
Free Cash Flow
$-25.0M
Total Assets
$765.0M
Cash Position
$250.5M

💡 AI Analyst Insight

Strong liquidity with a 2.17x current ratio provides a solid financial cushion.

CYRX Profit Margin, ROE & Profitability Analysis

Gross Margin 47.1%
Operating Margin -20.9%
Net Margin 44.4%
ROE 15.6%
ROA 10.2%
FCF Margin -14.2%

CYRX vs Healthcare Sector: How Cryoport, Inc. Compares

How Cryoport, Inc. compares to Healthcare sector averages

Net Margin
CYRX 44.4%
vs
Sector Avg 12.0%
CYRX Sector
ROE
CYRX 15.6%
vs
Sector Avg 15.0%
CYRX Sector
Current Ratio
CYRX 2.2x
vs
Sector Avg 2.0x
CYRX Sector
Debt/Equity
CYRX 0.2x
vs
Sector Avg 0.6x
CYRX Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Cryoport, Inc. Stock Overvalued? CYRX Valuation Analysis 2026

Based on fundamental analysis, Cryoport, Inc. appears fundamentally strong relative to the Healthcare sector in 2026.

Return on Equity
15.6%
Sector avg: 15%
Net Profit Margin
44.4%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.23x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Cryoport, Inc. Balance Sheet: CYRX Debt, Cash & Liquidity

Current Ratio
2.17x
Quick Ratio
2.07x
Debt/Equity
0.23x
Debt/Assets
34.3%
Interest Coverage
-27.51x
Long-term Debt
$115.0M

CYRX Revenue & Earnings Growth: 5-Year Financial Trend

CYRX 5-year financial data: Year 2024: Revenue $237.3M, Net Income -$37.3M, EPS $-0.93. Year 2025: Revenue $176.2M, Net Income -$99.6M, EPS $-2.21.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Cryoport, Inc.'s revenue has declined by 26% over the 5-year period, indicating business contraction. The most recent EPS of $-2.21 indicates the company is currently unprofitable.

CYRX Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-14.2%
Free cash flow / Revenue

CYRX Quarterly Earnings & Performance

Quarterly financial performance data for Cryoport, Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 $38.3M $805.0K $-0.02
Q2 2025 $39.7M -$78.0M $-1.62
Q1 2025 $37.3M -$12.0M $-0.28

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Cryoport, Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$8.6M
Cash generated from operations
Stock Buybacks
$10.0M
Shares repurchased (TTM)
Capital Expenditures
$16.4M
Investment in assets
Dividends
None
No dividend program

CYRX SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Cryoport, Inc. (CIK: 0001124524)

📋 Recent SEC Filings

Date Form Document Action
Apr 8, 2026 4 xslF345X06/tm2611424-1_4seq1.xml View →
Mar 25, 2026 4 xslF345X06/tm269766-3_4seq1.xml View →
Mar 25, 2026 4 xslF345X06/tm269766-2_4seq1.xml View →
Mar 25, 2026 4 xslF345X06/tm269766-1_4seq1.xml View →
Mar 17, 2026 4 xslF345X05/tm269014-4_4seq1.xml View →

Frequently Asked Questions about CYRX

What is the AI rating for CYRX?

Cryoport, Inc. (CYRX) has a Combined AI Rating of SELL from Claude (HOLD) and ChatGPT (SELL) with 68% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are CYRX's key strengths?

Claude: Strong net profit margin of 44.4% demonstrates pricing power and efficient cost management at bottom line. Healthy balance sheet with $250.5M cash, 2.17x current ratio, and conservative 0.23x debt/equity ratio providing financial flexibility. ChatGPT: Strong liquidity with $250.49M in cash and current ratio of 2.17x. Low balance-sheet leverage with debt/equity of 0.23x.

What are the risks of investing in CYRX?

Claude: Severe operating loss of $36.8M with -20.9% operating margin indicates core business is unprofitable despite net income gains. Negative free cash flow of -$25M with -$8.6M operating cash flow raises red flags about earnings quality and sustainability. ChatGPT: Operating losses remain significant with a -20.9% operating margin. Cash generation is weak, with negative operating cash flow and -$25.02M free cash flow.

What is CYRX's revenue and growth?

Cryoport, Inc. reported revenue of $176.2M.

Does CYRX pay dividends?

Cryoport, Inc. does not currently pay dividends.

Where can I find CYRX SEC filings?

Official SEC filings for Cryoport, Inc. (CIK: 0001124524) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is CYRX's EPS?

Cryoport, Inc. has a diluted EPS of $1.40.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is CYRX a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Cryoport, Inc. has a SELL rating with 68% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is CYRX stock overvalued or undervalued?

Valuation metrics for CYRX: ROE of 15.6% (sector avg: 15%), net margin of 44.4% (sector avg: 12%). Higher ROE suggests strong returns relative to peers.

Should I buy CYRX stock in 2026?

Our dual AI analysis gives Cryoport, Inc. a combined SELL rating for 2026. Revenue is data pending, with profitability above sector average. Always conduct your own research.

What is CYRX's free cash flow?

Cryoport, Inc.'s operating cash flow is $-8.6M, with capital expenditures of $16.4M. FCF margin is -14.2%.

How does CYRX compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin 44.4% (avg: 12%), ROE 15.6% (avg: 15%), current ratio 2.17 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Mar 23, 2026 | Data as of: 2025-12-31 | Powered by Claude AI