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CytomX Therapeutics, Inc. (CTMX) Fundamental Analysis & AI Grade 2026

CTMX Nasdaq Pharmaceutical Preparations DE CIK: 0001501989
Update Pending • Analysis: May 9, 2026 • SEC Data: 2026-03-31
Combined AI Grade
C
81% Confidence
AGREEMENT
C
73% Conf
D
89% Conf

📊 CTMX Key Takeaways

Revenue: $10.3M
Net Margin: -177.9%
Free Cash Flow: $-25.5M
Current Ratio: 10.38x
Debt/Equity: 0.00x
EPS: $0.00
AI Grade: C with 73% confidence
CytomX Therapeutics, Inc. (CTMX) receives a C fundamental grade with 81% confidence from our AI analysis based on SEC 10-K filings. With revenue of $10.3M, net profit margin of -177.9%, and return on equity (ROE) of -5.7%, CytomX Therapeutics, Inc. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete CTMX stock analysis for 2026.

Is CytomX Therapeutics, Inc. (CTMX) a Good Investment?

Claude

CytomX is burning $25.5M annually in operating cash while generating only $10.3M in flat-growth revenue, resulting in -177.9% net margins and negative returns on both equity and assets. Although the strong balance sheet ($28.8M cash, minimal debt) provides ~13 months of runway at current burn rates, the company faces imminent pressure to achieve profitability, raise capital (potentially dilutive), or achieve major revenue inflection with no evidence of near-term improvement.

ChatGPT

CytomX Therapeutics shows weak fundamental quality: revenue was flat, operating margins remain deeply negative, and free cash flow was severely negative relative to revenue. While the balance sheet is lightly levered and current liquidity ratios look healthy on paper, the cash balance is very small relative to the scale of annual operating cash burn, creating significant financing risk unless operating performance improves materially.

CytomX Therapeutics, Inc. Key Strengths (CTMX)

Claude
  • + Fortress balance sheet with $319.9M equity and only $1.6M debt
  • + Minimal leverage (0.00x debt/equity) provides financial flexibility
  • + Excellent liquidity (10.38x current ratio) for near-term obligations
ChatGPT
  • + Low leverage with debt/equity of 0.02x limits balance-sheet strain
  • + Current and quick ratios of 3.09x indicate acceptable near-term balance-sheet liquidity
  • + Net loss improved year over year, suggesting some expense discipline or non-operating improvement

CTMX Stock Risks: CytomX Therapeutics, Inc. Investment Risks

Claude
  • ! Severe cash burn of $25.5M annually with only ~13 months of runway at current rate
  • ! Zero revenue growth YoY despite operating losses exceeding revenue by 1.9x
  • ! Operating margin of -191.8% indicates core business model not generating returns
  • ! Negative ROE (-5.7%) and ROA (-5.1%) destroying shareholder and asset value
  • ! Pharmaceutical sector maturity required but company shows minimal revenue generation capability
  • ! Likely future capital raise or asset sale needed within 12-18 months
ChatGPT
  • ! Operating cash flow of -$75.59M versus only $12.67M in cash implies a very short cash runway
  • ! Revenue growth of 0.0% indicates weak top-line momentum and poor growth quality
  • ! Negative operating margin, net margin, ROE, and ROA show the business remains structurally unprofitable

Key Metrics to Watch

Claude
  • * Quarterly cash burn trend and cash runway forecast
  • * Revenue growth inflection or major commercial milestone announcements
  • * Clinical pipeline progress and regulatory approval timelines
  • * Operating expense reduction initiatives or restructuring plans
  • * Capital raise announcements and dilution impact
ChatGPT
  • * Quarterly operating cash burn relative to cash and equivalents
  • * Revenue growth and operating margin improvement

CytomX Therapeutics, Inc. (CTMX) Financial Metrics & Key Ratios

Revenue
$10.3M
Net Income
$-18.2M
EPS (Diluted)
$0.00
Free Cash Flow
$-25.5M
Total Assets
$359.4M
Cash Position
$28.8M

💡 AI Analyst Insight

Strong liquidity with a 10.38x current ratio provides a solid financial cushion.

CTMX Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin -191.8%
Net Margin -177.9%
ROE -5.7%
ROA -5.1%
FCF Margin -249.1%

CTMX vs Healthcare Sector: How CytomX Therapeutics, Inc. Compares

How CytomX Therapeutics, Inc. compares to Healthcare sector averages

Net Margin
CTMX -177.9%
vs
Sector Avg 12.0%
CTMX Sector
ROE
CTMX -5.7%
vs
Sector Avg 15.0%
CTMX Sector
Current Ratio
CTMX 10.4x
vs
Sector Avg 2.0x
CTMX Sector
Debt/Equity
CTMX 0.0x
vs
Sector Avg 0.6x
CTMX Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is CytomX Therapeutics, Inc. Stock Overvalued? CTMX Valuation Analysis 2026

Based on fundamental analysis, CytomX Therapeutics, Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-5.7%
Sector avg: 15%
Net Profit Margin
-177.9%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

CytomX Therapeutics, Inc. Balance Sheet: CTMX Debt, Cash & Liquidity

Current Ratio
10.38x
Quick Ratio
10.38x
Debt/Equity
0.00x
Debt/Assets
11.0%
Interest Coverage
-95.50x
Long-term Debt
$1.6M

CTMX Revenue & Earnings Growth: 5-Year Financial Trend

CTMX 5-year financial data: Year 2021: Revenue $100.4M, Net Income -$102.2M, EPS N/A. Year 2022: Revenue $53.2M, Net Income -$115.9M, EPS $-1.81. Year 2023: Revenue $101.2M, Net Income -$99.3M, EPS $-1.51. Year 2024: Revenue $138.1M, Net Income -$569.0K, EPS $-0.01. Year 2025: Revenue $138.1M, Net Income $31.9M, EPS $0.38.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: CytomX Therapeutics, Inc.'s revenue has grown significantly by 38% over the 5-year period, indicating strong business expansion. The most recent EPS of $0.38 reflects profitable operations.

CTMX Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-249.1%
Free cash flow / Revenue

CTMX Quarterly Earnings & Performance

Quarterly financial performance data for CytomX Therapeutics, Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q1 2026 $10.3M -$18.2M $-0.10
Q3 2025 $6.0M -$154.0K $0.07
Q2 2025 $18.7M -$154.0K $0.00
Q1 2025 $41.5M $13.8M $0.17
Q3 2024 $26.4M -$1.1M $-0.02
Q2 2024 $24.7M -$1.1M $-0.02
Q1 2024 $23.5M -$3.3M $-0.05
Q3 2023 $11.1M -$1.1M $-0.02

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

CytomX Therapeutics, Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$25.5M
Cash generated from operations
Dividends
None
No dividend program

CTMX SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for CytomX Therapeutics, Inc. (CIK: 0001501989)

📋 Recent SEC Filings

Date Form Document Action
Jun 3, 2026 8-K d66030d8k.htm View →
May 7, 2026 8-K ctmx-20260507.htm View →
May 7, 2026 10-Q ctmx-20260331.htm View →
Apr 30, 2026 DEF 14A ny20064651x2_def14a.htm View →
Mar 19, 2026 4 xslF345X06/form4.xml View →

Frequently Asked Questions about CTMX

What is the AI rating for CTMX?

CytomX Therapeutics, Inc. (CTMX) has a Combined AI Grade of C from Claude (C) and ChatGPT (D) with 81% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are CTMX's key strengths?

Claude: Fortress balance sheet with $319.9M equity and only $1.6M debt. Minimal leverage (0.00x debt/equity) provides financial flexibility. ChatGPT: Low leverage with debt/equity of 0.02x limits balance-sheet strain. Current and quick ratios of 3.09x indicate acceptable near-term balance-sheet liquidity.

What are the risks of investing in CTMX?

Claude: Severe cash burn of $25.5M annually with only ~13 months of runway at current rate. Zero revenue growth YoY despite operating losses exceeding revenue by 1.9x. ChatGPT: Operating cash flow of -$75.59M versus only $12.67M in cash implies a very short cash runway. Revenue growth of 0.0% indicates weak top-line momentum and poor growth quality.

What is CTMX's revenue and growth?

CytomX Therapeutics, Inc. reported revenue of $10.3M.

Does CTMX pay dividends?

CytomX Therapeutics, Inc. does not currently pay dividends.

Where can I find CTMX SEC filings?

Official SEC filings for CytomX Therapeutics, Inc. (CIK: 0001501989) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is CTMX's EPS?

CytomX Therapeutics, Inc. has a diluted EPS of $0.00.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined grade reflects both perspectives for balanced insights.

What is CTMX's fundamental grade?

Based on our AI fundamental analysis in June 2026, CytomX Therapeutics, Inc. has a C grade with 81% confidence. Review the strengths and risks sections above for full context. This is not investment advice.

Is CTMX stock overvalued or undervalued?

Valuation metrics for CTMX: ROE of -5.7% (sector avg: 15%), net margin of -177.9% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

What is CTMX's AI grade for 2026?

Our dual AI analysis gives CytomX Therapeutics, Inc. a combined C grade for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is CTMX's free cash flow?

CytomX Therapeutics, Inc.'s operating cash flow is $-25.5M, with capital expenditures of $0.0. FCF margin is -249.1%.

How does CTMX compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -177.9% (avg: 12%), ROE -5.7% (avg: 15%), current ratio 10.38 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: May 9, 2026 | Data as of: 2026-03-31 | Powered by Claude AI