← Back to All US Stocks

Clene Inc. (CLNN) Stock Fundamental Analysis & AI Rating 2026

CLNN Nasdaq Pharmaceutical Preparations DE CIK: 0001822791
Updated This Month • Analysis: Mar 22, 2026 • SEC Data: 2025-12-31
Combined AI Rating
STRONG SELL
94% Confidence
STRONG AGREEMENT
STRONG SELL
95% Conf
STRONG SELL
92% Conf

📊 CLNN Key Takeaways

Revenue: $200.0K
Net Margin: -13,086.5%
Free Cash Flow: $-18.6M
Current Ratio: 0.83x
Debt/Equity: N/A
EPS: $-0.46
AI Rating: STRONG SELL with 95% confidence
Clene Inc. (CLNN) receives a STRONG SELL rating with 94% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $200.0K, net profit margin of -13,086.5%, Clene Inc. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete CLNN stock analysis for 2026.

Is Clene Inc. (CLNN) a Good Investment?

Claude

Clene Inc. exhibits severe financial distress with negative stockholders' equity of -$17.6M, massive operating losses, and critically weak liquidity. The company is burning cash at an unsustainable rate (-$18.6M FCF) with minimal revenue generation ($200K), indicating the business model is not viable in its current state and poses significant financial risk.

ChatGPT

Clene Inc.'s fundamentals are extremely weak, with minimal revenue, deeply negative operating and net margins, and free cash flow losses that are vastly larger than sales. The balance sheet is stressed by negative equity, sub-1.0 liquidity, and meaningful long-term debt, while the modest year-over-year improvement in net loss does not offset the company's severe cash burn and limited commercial traction.

Why Buy Clene Inc. Stock? CLNN Key Strengths

Claude
  • + Maintains modest cash position of $5.2M providing short-term runway
  • + Revenue generation demonstrates some commercial traction despite minimal scale
  • + High insider activity (25 Form 4 filings) may indicate management confidence or restructuring efforts
ChatGPT
  • + Net loss improved year over year, indicating some expense discipline versus the prior period
  • + The company still holds cash on hand, providing limited near-term operating flexibility
  • + Capital expenditure needs are currently low, which reduces additional cash demands from fixed investment

CLNN Stock Risks: Clene Inc. Investment Risks

Claude
  • ! Negative stockholders' equity of -$17.6M indicates technical insolvency and shareholder value destruction
  • ! Operating cash burn of -$18.5M annually with only $5.2M cash on hand creates critical liquidity crisis
  • ! Revenue collapsed 41.5% YoY to just $200K while operating losses remain severe at -$23.1M
  • ! Liabilities ($35.7M) exceed assets ($18.1M) by 97%, indicating structural financial failure
  • ! Current ratio of 0.83x shows inability to cover short-term obligations with current assets
  • ! Long-term debt of $17.8M is unsustainable given negative cash generation and minimal revenue
ChatGPT
  • ! Revenue is extremely small and declined 41.5% year over year, signaling weak growth quality and limited commercialization
  • ! Negative stockholders' equity and a current ratio of 0.83x indicate financial distress and constrained balance-sheet flexibility
  • ! Operating cash flow and free cash flow are deeply negative, creating ongoing funding risk and potential reliance on external capital

Key Metrics to Watch

Claude
  • * Quarterly cash burn rate and months of runway remaining
  • * Revenue trajectory and path to profitability viability
  • * Stockholders' equity recovery through financing or operational improvement
  • * Operating cash flow inflection point
ChatGPT
  • * Quarterly cash burn relative to cash balance
  • * Revenue growth and operating loss trend

Clene Inc. (CLNN) Financial Metrics & Key Ratios

Revenue
$200.0K
Net Income
$-26.2M
EPS (Diluted)
$-0.46
Free Cash Flow
$-18.6M
Total Assets
$18.1M
Cash Position
$5.2M

💡 AI Analyst Insight

The current ratio below 1.0x warrants monitoring of short-term liquidity.

CLNN Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin -11,541.5%
Net Margin -13,086.5%
ROE N/A
ROA -144.4%
FCF Margin -9,292.5%

CLNN vs Healthcare Sector: How Clene Inc. Compares

How Clene Inc. compares to Healthcare sector averages

Net Margin
CLNN -13,086.5%
vs
Sector Avg 12.0%
CLNN Sector
ROE
CLNN 0.0%
vs
Sector Avg 15.0%
CLNN Sector
Current Ratio
CLNN 0.8x
vs
Sector Avg 2.0x
CLNN Sector
Debt/Equity
CLNN 0.0x
vs
Sector Avg 0.6x
CLNN Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Clene Inc. Stock Overvalued? CLNN Valuation Analysis 2026

Based on fundamental analysis, Clene Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
N/A
Sector avg: 15%
Net Profit Margin
-13,086.5%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
N/A
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Clene Inc. Balance Sheet: CLNN Debt, Cash & Liquidity

Current Ratio
0.83x
Quick Ratio
0.83x
Debt/Equity
N/A
Debt/Assets
197.0%
Interest Coverage
-8.61x
Long-term Debt
$17.8M

CLNN Revenue & Earnings Growth: 5-Year Financial Trend

CLNN 5-year financial data: Year 2022: Revenue $723.0K, Net Income -$9.7M, EPS $-0.16.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Clene Inc.'s revenue has remained relatively flat over the 5-year period, with a 0% decline. The most recent EPS of $-5.67 indicates the company is currently unprofitable.

CLNN Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-9,292.5%
Free cash flow / Revenue

CLNN Quarterly Earnings & Performance

Quarterly financial performance data for Clene Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 $15.0K -$751.0K $-0.85
Q2 2025 $27.0K -$751.0K $-0.78
Q1 2025 $73.0K -$751.0K $-0.09
Q3 2024 $87.0K -$2.4M $-0.38
Q2 2024 $91.0K -$6.8M $-1.06
Q1 2024 $73.0K -$11.1M $-0.09
Q3 2023 $108.0K -$2.4M $-0.02
Q2 2023 $35.0K -$4.5M $-0.07

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Clene Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$18.5M
Cash generated from operations
Capital Expenditures
$39.0K
Investment in assets
Dividends
None
No dividend program

CLNN SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Clene Inc. (CIK: 0001822791)

📋 Recent SEC Filings

Date Form Document Action
Apr 10, 2026 DEF 14A clnn20250512_def14a.htm View →
Apr 6, 2026 4 xslF345X06/primary_doc.xml View →
Apr 1, 2026 4 xslF345X06/primary_doc.xml View →
Mar 31, 2026 4 xslF345X06/primary_doc.xml View →
Mar 26, 2026 4 xslF345X06/primary_doc.xml View →

Frequently Asked Questions about CLNN

What is the AI rating for CLNN?

Clene Inc. (CLNN) has a Combined AI Rating of STRONG SELL from Claude (STRONG SELL) and ChatGPT (STRONG SELL) with 94% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are CLNN's key strengths?

Claude: Maintains modest cash position of $5.2M providing short-term runway. Revenue generation demonstrates some commercial traction despite minimal scale. ChatGPT: Net loss improved year over year, indicating some expense discipline versus the prior period. The company still holds cash on hand, providing limited near-term operating flexibility.

What are the risks of investing in CLNN?

Claude: Negative stockholders' equity of -$17.6M indicates technical insolvency and shareholder value destruction. Operating cash burn of -$18.5M annually with only $5.2M cash on hand creates critical liquidity crisis. ChatGPT: Revenue is extremely small and declined 41.5% year over year, signaling weak growth quality and limited commercialization. Negative stockholders' equity and a current ratio of 0.83x indicate financial distress and constrained balance-sheet flexibility.

What is CLNN's revenue and growth?

Clene Inc. reported revenue of $200.0K.

Does CLNN pay dividends?

Clene Inc. does not currently pay dividends.

Where can I find CLNN SEC filings?

Official SEC filings for Clene Inc. (CIK: 0001822791) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is CLNN's EPS?

Clene Inc. has a diluted EPS of $-0.46.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is CLNN a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Clene Inc. has a STRONG SELL rating with 94% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is CLNN stock overvalued or undervalued?

Valuation metrics for CLNN: ROE of N/A (sector avg: 15%), net margin of -13,086.5% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy CLNN stock in 2026?

Our dual AI analysis gives Clene Inc. a combined STRONG SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is CLNN's free cash flow?

Clene Inc.'s operating cash flow is $-18.5M, with capital expenditures of $39.0K. FCF margin is -9,292.5%.

How does CLNN compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -13,086.5% (avg: 12%), ROE N/A (avg: 15%), current ratio 0.83 (avg: 2).

Top Rated Stocks
NSSC 92% MLI 92% MELI 92% MDXG 92% MANH 92% INVA 92% GGG 92% GCT 92% FTNT 92% FSLR 92%
Sector: All Healthcare Stocks →
Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Mar 22, 2026 | Data as of: 2025-12-31 | Powered by Claude AI