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CalciMedica, Inc. (CALC) Stock Fundamental Analysis & AI Rating 2026

CALC Nasdaq Pharmaceutical Preparations DE CIK: 0001534133
Updated This Month • Analysis: Mar 21, 2026 • SEC Data: 2025-12-31
Combined AI Rating
STRONG SELL
94% Confidence
STRONG AGREEMENT
STRONG SELL
95% Conf
STRONG SELL
92% Conf

📊 CALC Key Takeaways

Revenue: $713.0K
Net Margin: -4,146.1%
Free Cash Flow: $-21.2M
Current Ratio: 3.58x
Debt/Equity: N/A
EPS: $-1.97
AI Rating: STRONG SELL with 95% confidence
CalciMedica, Inc. (CALC) receives a STRONG SELL rating with 94% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $713.0K, net profit margin of -4,146.1%, CalciMedica, Inc. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete CALC stock analysis for 2026.

Is CalciMedica, Inc. (CALC) a Good Investment?

Claude

CalciMedica is a pre-revenue/early-stage biotech company with severe financial distress, evidenced by negative stockholders' equity of -$6.6M and liabilities exceeding assets by $6.6M. The company is burning cash at an unsustainable rate with -$21.2M operating cash flow against only $11.5M in cash reserves, projecting less than 6 months of runway at current burn rates. Without significant financing, clinical progress, or a clear path to profitability, the equity faces substantial dilution risk or potential insolvency.

ChatGPT

CalciMedica’s fundamentals are extremely weak: revenue is small and declining, while operating losses, net losses, and free cash outflow are vastly larger than the top line. Although liquidity is currently supported by a solid cash balance and strong current ratio, negative equity and sustained cash burn indicate a fragile financial position that likely depends on future external funding rather than internally generated business strength.

Why Buy CalciMedica, Inc. Stock? CALC Key Strengths

Claude
  • + Maintains positive current ratio of 3.58x relative to current liabilities
  • + Holds $11.5M in cash equivalents providing near-term operational flexibility
  • + Operating in pharmaceutical sector with potential for high-value therapeutic breakthroughs
ChatGPT
  • + Cash and equivalents of $11.52M provide near-term liquidity support
  • + Current and quick ratios of 3.58x indicate acceptable short-term balance sheet liquidity
  • + Capital expenditure is minimal, limiting additional fixed-asset cash demands

CALC Stock Risks: CalciMedica, Inc. Investment Risks

Claude
  • ! Negative stockholders' equity of -$6.6M indicates liabilities exceed assets; equity holders in subordinate position
  • ! Operating cash burn of -$21.2M annually with only $11.5M cash runway (~6 months at current rate)
  • ! Revenue collapse of -29.7% YoY with minimal revenue generation ($713K) indicates failed commercialization or delayed clinical progress
  • ! Operating margin of -3242.8% demonstrates pre-commercial stage with no path to profitability visible in near term
  • ! No insider buying activity in last 90 days suggests lack of management confidence
  • ! Dependency on external financing creates severe dilution risk for existing shareholders
ChatGPT
  • ! Revenue declined 29.7% YoY and remains far too small to support the cost structure
  • ! Net loss of $29.56M and free cash flow of -$21.21M reflect severe ongoing cash burn
  • ! Negative stockholders’ equity of -$6.64M signals balance-sheet weakness and potential future financing pressure

Key Metrics to Watch

Claude
  • * Cash runway and next financing timeline
  • * Clinical trial progression and regulatory milestones
  • * Quarterly cash burn rate and operating cash flow trends
  • * Revenue growth trajectory and commercial product launches
  • * Debt restructuring or capital raise announcements
ChatGPT
  • * Quarterly operating cash burn relative to cash balance
  • * Revenue trajectory and whether operating losses narrow materially

CalciMedica, Inc. (CALC) Financial Metrics & Key Ratios

Revenue
$713.0K
Net Income
$-29.6M
EPS (Diluted)
$-1.97
Free Cash Flow
$-21.2M
Total Assets
$13.6M
Cash Position
$11.5M

💡 AI Analyst Insight

Strong liquidity with a 3.58x current ratio provides a solid financial cushion.

CALC Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin -3,242.8%
Net Margin -4,146.1%
ROE N/A
ROA -217.5%
FCF Margin -2,974.2%

CALC vs Healthcare Sector: How CalciMedica, Inc. Compares

How CalciMedica, Inc. compares to Healthcare sector averages

Net Margin
CALC -4,146.1%
vs
Sector Avg 12.0%
CALC Sector
ROE
CALC 0.0%
vs
Sector Avg 15.0%
CALC Sector
Current Ratio
CALC 3.6x
vs
Sector Avg 2.0x
CALC Sector
Debt/Equity
CALC 0.0x
vs
Sector Avg 0.6x
CALC Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is CalciMedica, Inc. Stock Overvalued? CALC Valuation Analysis 2026

Based on fundamental analysis, CalciMedica, Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
N/A
Sector avg: 15%
Net Profit Margin
-4,146.1%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
N/A
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

CalciMedica, Inc. Balance Sheet: CALC Debt, Cash & Liquidity

Current Ratio
3.58x
Quick Ratio
3.58x
Debt/Equity
N/A
Debt/Assets
148.9%
Interest Coverage
N/A
Long-term Debt
N/A

CALC Revenue & Earnings Growth: 5-Year Financial Trend

CALC 5-year financial data:
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: CalciMedica, Inc.'s revenue has remained relatively flat over the 5-year period, with a 0% decline. The most recent EPS of $-1.22 indicates the company is currently unprofitable.

CALC Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-2,974.2%
Free cash flow / Revenue

CalciMedica, Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$21.2M
Cash generated from operations
Capital Expenditures
$28.0K
Investment in assets
Dividends
None
No dividend program

CALC SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for CalciMedica, Inc. (CIK: 0001534133)

📋 Recent SEC Filings

Date Form Document Action
Apr 7, 2026 4 xslF345X06/form4-04072026_090411.xml View →
Apr 7, 2026 4 xslF345X06/form4-04072026_090409.xml View →
Apr 7, 2026 4 xslF345X06/form4-04072026_090407.xml View →
Apr 7, 2026 4 xslF345X06/form4-04072026_090405.xml View →
Apr 7, 2026 4 xslF345X06/form4-04072026_090404.xml View →

Frequently Asked Questions about CALC

What is the AI rating for CALC?

CalciMedica, Inc. (CALC) has a Combined AI Rating of STRONG SELL from Claude (STRONG SELL) and ChatGPT (STRONG SELL) with 94% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are CALC's key strengths?

Claude: Maintains positive current ratio of 3.58x relative to current liabilities. Holds $11.5M in cash equivalents providing near-term operational flexibility. ChatGPT: Cash and equivalents of $11.52M provide near-term liquidity support. Current and quick ratios of 3.58x indicate acceptable short-term balance sheet liquidity.

What are the risks of investing in CALC?

Claude: Negative stockholders' equity of -$6.6M indicates liabilities exceed assets; equity holders in subordinate position. Operating cash burn of -$21.2M annually with only $11.5M cash runway (~6 months at current rate). ChatGPT: Revenue declined 29.7% YoY and remains far too small to support the cost structure. Net loss of $29.56M and free cash flow of -$21.21M reflect severe ongoing cash burn.

What is CALC's revenue and growth?

CalciMedica, Inc. reported revenue of $713.0K.

Does CALC pay dividends?

CalciMedica, Inc. does not currently pay dividends.

Where can I find CALC SEC filings?

Official SEC filings for CalciMedica, Inc. (CIK: 0001534133) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is CALC's EPS?

CalciMedica, Inc. has a diluted EPS of $-1.97.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is CALC a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, CalciMedica, Inc. has a STRONG SELL rating with 94% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is CALC stock overvalued or undervalued?

Valuation metrics for CALC: ROE of N/A (sector avg: 15%), net margin of -4,146.1% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy CALC stock in 2026?

Our dual AI analysis gives CalciMedica, Inc. a combined STRONG SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is CALC's free cash flow?

CalciMedica, Inc.'s operating cash flow is $-21.2M, with capital expenditures of $28.0K. FCF margin is -2,974.2%.

How does CALC compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -4,146.1% (avg: 12%), ROE N/A (avg: 15%), current ratio 3.58 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Mar 21, 2026 | Data as of: 2025-12-31 | Powered by Claude AI