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Barinthus Biotherapeutics plc. (BRNS) Stock Fundamental Analysis & AI Rating 2026

BRNS Nasdaq Pharmaceutical Preparations X0 CIK: 0001828185
Updated This Month • Analysis: Mar 21, 2026 • SEC Data: 2025-12-31
Combined AI Rating
SELL
84% Confidence
AGREEMENT
STRONG SELL
92% Conf
SELL
77% Conf

📊 BRNS Key Takeaways

Revenue: $0.0
Net Margin: N/A
Free Cash Flow: $-48.0M
Current Ratio: 7.77x
Debt/Equity: 0.00x
EPS: $-1.64
AI Rating: STRONG SELL with 92% confidence
Barinthus Biotherapeutics plc. (BRNS) receives a SELL rating with 84% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $0, and return on equity (ROE) of -89.5%, Barinthus Biotherapeutics plc. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete BRNS stock analysis for 2026.

Is Barinthus Biotherapeutics plc. (BRNS) a Good Investment?

Claude

Barinthus is a pre-revenue biopharmaceutical company in clinical development with no product sales, generating -$66.4M net losses and -$48.0M operating cash burn. Despite adequate cash reserves of $70.5M providing 12-14 months of runway at current burn rates, the company faces existential risk with zero revenue generation, deeply negative profitability metrics (ROE -89.5%, ROA -67.7%), and no demonstrated path to commercialization or profitability.

ChatGPT

Barinthus Biotherapeutics shows the typical profile of a pre-revenue biotech with no current commercial traction, large operating losses, and deeply negative returns on equity and assets. Its balance sheet is a meaningful offset, with substantial cash, strong liquidity, and no long-term debt, but the current fundamentals depend heavily on continued cash funding rather than internally generated business performance. Until revenue generation or a clear improvement in cash burn emerges, the fundamental profile remains weak.

Why Buy Barinthus Biotherapeutics plc. Stock? BRNS Key Strengths

Claude
  • + Strong liquidity position with $70.5M cash and 7.77x current ratio
  • + No long-term debt providing financial flexibility
  • + Adequate working capital to fund near-term operations
ChatGPT
  • + Strong liquidity with $70.46M in cash and current ratio of 7.77x
  • + Debt-free balance sheet reduces financial distress risk
  • + Equity base remains positive at $74.21M, providing some balance sheet cushion

BRNS Stock Risks: Barinthus Biotherapeutics plc. Investment Risks

Claude
  • ! Zero revenue with -100% YoY decline indicates failed commercialization or clinical programs
  • ! Severe cash burn of -$48.0M annually will exhaust reserves within 12-14 months without capital raise
  • ! No product portfolio generating revenue; entirely dependent on clinical trial success with high failure risk
  • ! Negative ROE (-89.5%) and ROA (-67.7%) indicate value destruction and poor asset utilization
  • ! No insider buying activity suggests limited management confidence in company direction
ChatGPT
  • ! Zero revenue and no gross profit indicate no current operating business scalability
  • ! Large annual net loss of $66.43M and negative free cash flow of $48.02M imply continued capital consumption
  • ! Negative ROE and ROA show weak capital efficiency and poor underlying profitability

Key Metrics to Watch

Claude
  • * Cash balance and runway - critical indicator of survival timeline
  • * Clinical trial progression and regulatory milestones for pipeline candidates
  • * Operating cash flow trend and achievement of clinical endpoints
  • * Potential capital raises or financing events to extend runway
  • * Revenue generation from any approved or commercialized products
ChatGPT
  • * Quarterly cash burn relative to cash balance
  • * Any sustained revenue generation from partnerships, licensing, or commercialization

Barinthus Biotherapeutics plc. (BRNS) Financial Metrics & Key Ratios

Revenue
$0.0
Net Income
$-66.4M
EPS (Diluted)
$-1.64
Free Cash Flow
$-48.0M
Total Assets
$98.2M
Cash Position
$70.5M

💡 AI Analyst Insight

Strong liquidity with a 7.77x current ratio provides a solid financial cushion.

BRNS Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin N/A
Net Margin N/A
ROE -89.5%
ROA -67.7%
FCF Margin N/A

BRNS vs Healthcare Sector: How Barinthus Biotherapeutics plc. Compares

How Barinthus Biotherapeutics plc. compares to Healthcare sector averages

Net Margin
BRNS 0.0%
vs
Sector Avg 12.0%
BRNS Sector
ROE
BRNS -89.5%
vs
Sector Avg 15.0%
BRNS Sector
Current Ratio
BRNS 7.8x
vs
Sector Avg 2.0x
BRNS Sector
Debt/Equity
BRNS 0.0x
vs
Sector Avg 0.6x
BRNS Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Barinthus Biotherapeutics plc. Stock Overvalued? BRNS Valuation Analysis 2026

Based on fundamental analysis, Barinthus Biotherapeutics plc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-89.5%
Sector avg: 15%
Net Profit Margin
N/A
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Barinthus Biotherapeutics plc. Balance Sheet: BRNS Debt, Cash & Liquidity

Current Ratio
7.77x
Quick Ratio
7.77x
Debt/Equity
0.00x
Debt/Assets
24.3%
Interest Coverage
-5,879.58x
Long-term Debt
N/A

BRNS Revenue & Earnings Growth: 5-Year Financial Trend

BRNS 5-year financial data: Year 2021: Revenue $4.8M, Net Income -$17.7M, EPS $-2.24. Year 2022: Revenue $44.7M, Net Income -$50.9M, EPS $-1.96. Year 2023: Revenue $44.7M, Net Income $5.3M, EPS $0.14. Year 2024: Revenue $15.0M, Net Income -$73.3M, EPS $-1.91. Year 2025: Revenue $15.0M, Net Income -$61.1M, EPS $-1.55.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Barinthus Biotherapeutics plc.'s revenue has grown significantly by 210% over the 5-year period, indicating strong business expansion. The most recent EPS of $-1.55 indicates the company is currently unprofitable.

BRNS Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
N/A
Free cash flow / Revenue

BRNS Quarterly Earnings & Performance

Quarterly financial performance data for Barinthus Biotherapeutics plc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 N/A -$8.1M $-0.21
Q3 2024 N/A -$8.1M $-0.21
Q2 2024 N/A -$16.9M $-0.43
Q1 2024 N/A -$15.5M $-0.40
Q3 2023 $802.0K $8.2M $0.22
Q2 2023 $334.0K $15.7M $0.41
Q1 2023 $468.0K $2.6M $0.07
Q3 2022 $19.0K -$4.6M $-0.13

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Barinthus Biotherapeutics plc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$48.0M
Cash generated from operations
Capital Expenditures
$37.0K
Investment in assets
Dividends
None
No dividend program

BRNS SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Barinthus Biotherapeutics plc. (CIK: 0001828185)

📋 Recent SEC Filings

Date Form Document Action
Mar 31, 2026 8-K tm2610673d1_8k.htm View →
Mar 13, 2026 10-K brns-20251231.htm View →
Mar 13, 2026 8-K brns-20260313.htm View →
Feb 23, 2026 8-K tm266347d1_8k.htm View →
Jan 6, 2026 8-K brns-20251230.htm View →

Frequently Asked Questions about BRNS

What is the AI rating for BRNS?

Barinthus Biotherapeutics plc. (BRNS) has a Combined AI Rating of SELL from Claude (STRONG SELL) and ChatGPT (SELL) with 84% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are BRNS's key strengths?

Claude: Strong liquidity position with $70.5M cash and 7.77x current ratio. No long-term debt providing financial flexibility. ChatGPT: Strong liquidity with $70.46M in cash and current ratio of 7.77x. Debt-free balance sheet reduces financial distress risk.

What are the risks of investing in BRNS?

Claude: Zero revenue with -100% YoY decline indicates failed commercialization or clinical programs. Severe cash burn of -$48.0M annually will exhaust reserves within 12-14 months without capital raise. ChatGPT: Zero revenue and no gross profit indicate no current operating business scalability. Large annual net loss of $66.43M and negative free cash flow of $48.02M imply continued capital consumption.

What is BRNS's revenue and growth?

Barinthus Biotherapeutics plc. reported revenue of $0.0.

Does BRNS pay dividends?

Barinthus Biotherapeutics plc. does not currently pay dividends.

Where can I find BRNS SEC filings?

Official SEC filings for Barinthus Biotherapeutics plc. (CIK: 0001828185) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is BRNS's EPS?

Barinthus Biotherapeutics plc. has a diluted EPS of $-1.64.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is BRNS a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Barinthus Biotherapeutics plc. has a SELL rating with 84% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is BRNS stock overvalued or undervalued?

Valuation metrics for BRNS: ROE of -89.5% (sector avg: 15%), net margin of N/A (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy BRNS stock in 2026?

Our dual AI analysis gives Barinthus Biotherapeutics plc. a combined SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is BRNS's free cash flow?

Barinthus Biotherapeutics plc.'s operating cash flow is $-48.0M, with capital expenditures of $37.0K.

How does BRNS compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin N/A (avg: 12%), ROE -89.5% (avg: 15%), current ratio 7.77 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Mar 21, 2026 | Data as of: 2025-12-31 | Powered by Claude AI