← Back to All US Stocks

Biomea Fusion, Inc. (BMEA) Fundamental Analysis & AI Grade 2026

BMEA Nasdaq Pharmaceutical Preparations DE CIK: 0001840439
Updated This Month • Analysis: May 12, 2026 • SEC Data: 2026-03-31
Combined AI Grade
D
82% Confidence
STRONG AGREEMENT
D
78% Conf
D
86% Conf

📊 BMEA Key Takeaways

Revenue: $430.0K
Net Margin: -2,887.2%
Free Cash Flow: $-11.7M
Current Ratio: 4.98x
Debt/Equity: 0.00x
EPS: $-0.17
AI Grade: D with 78% confidence
Biomea Fusion, Inc. (BMEA) receives a D fundamental grade with 82% confidence from our AI analysis based on SEC 10-K filings. With revenue of $430.0K, net profit margin of -2,887.2%, and return on equity (ROE) of -66.3%, Biomea Fusion, Inc. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete BMEA stock analysis for 2026.

Is Biomea Fusion, Inc. (BMEA) a Good Investment?

Claude

Biomea Fusion is a pre-revenue biotech firm with catastrophic cash burn ($11.7M quarterly operating loss) against minimal revenue ($430K, declining 67% YoY), leaving no margin for safety in operations. Despite adequate cash reserves ($44.7M), the company's fundamentals show value destruction at all levels—negative ROE/ROA, zero commercial traction, and a burn rate that exhausts runway within 12-15 months without additional capital or revenue inflection.

ChatGPT

Biomea Fusion’s fundamentals are very weak: the company is generating only modest revenue while posting extremely large operating and net losses, with deeply negative margins and returns on capital. Although the balance sheet is not debt-burdened and near-term liquidity is still adequate, the current cash burn appears too high relative to its cash balance, making the business heavily dependent on improving operating performance or raising additional capital.

Biomea Fusion, Inc. Key Strengths (BMEA)

Claude
  • + Debt-free balance sheet with zero leverage (Debt/Equity 0.00x)
  • + Strong liquidity position (Current Ratio 4.98x) for near-term obligations
  • + Adequate cash reserves ($44.7M) providing operational runway
ChatGPT
  • + Strong current liquidity with a 3.18x current and quick ratio
  • + No meaningful long-term debt, limiting balance-sheet leverage risk
  • + Cash balances of $46.64M still provide short-term operating flexibility

BMEA Stock Risks: Biomea Fusion, Inc. Investment Risks

Claude
  • ! Acute cash burn of $11.7M per quarter with minimal revenue—reserves deplete in 12-15 months
  • ! Revenue collapsed 67% YoY to $430K—no evidence of commercial product viability
  • ! Extreme negative margins (Operating: -2971%, Net: -2887%) indicate unsustainable development-stage losses
  • ! No visible path to profitability or commercial traction in SEC filings
ChatGPT
  • ! Operating and net margins are severely negative, indicating an unsustainable cost structure
  • ! Operating cash flow and free cash flow are deeply negative, implying substantial ongoing cash burn
  • ! Very low equity base relative to losses raises the risk of future dilution or financial strain

Key Metrics to Watch

Claude
  • * Quarterly revenue growth (reversed negative 67% decline)
  • * Operating cash burn rate (absolute dollars, trajectory toward breakeven)
  • * Cash runway (months until depletion at current burn rate)
  • * Clinical trial advancement or FDA milestone achievements
ChatGPT
  • * Quarterly operating cash burn relative to cash and equivalents
  • * Revenue progression versus operating expense growth

Biomea Fusion, Inc. (BMEA) Financial Metrics & Key Ratios

Revenue
$430.0K
Net Income
$-12.4M
EPS (Diluted)
$-0.17
Free Cash Flow
$-11.7M
Total Assets
$46.4M
Cash Position
$44.7M

💡 AI Analyst Insight

Strong liquidity with a 4.98x current ratio provides a solid financial cushion.

BMEA Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin -2,970.7%
Net Margin -2,887.2%
ROE -66.3%
ROA -26.8%
FCF Margin -2,713.7%

BMEA vs Healthcare Sector: How Biomea Fusion, Inc. Compares

How Biomea Fusion, Inc. compares to Healthcare sector averages

Net Margin
BMEA -2,887.2%
vs
Sector Avg 12.0%
BMEA Sector
ROE
BMEA -66.3%
vs
Sector Avg 15.0%
BMEA Sector
Current Ratio
BMEA 5.0x
vs
Sector Avg 2.0x
BMEA Sector
Debt/Equity
BMEA 0.0x
vs
Sector Avg 0.6x
BMEA Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Biomea Fusion, Inc. Stock Overvalued? BMEA Valuation Analysis 2026

Based on fundamental analysis, Biomea Fusion, Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-66.3%
Sector avg: 15%
Net Profit Margin
-2,887.2%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Biomea Fusion, Inc. Balance Sheet: BMEA Debt, Cash & Liquidity

Current Ratio
4.98x
Quick Ratio
4.98x
Debt/Equity
0.00x
Debt/Assets
59.6%
Interest Coverage
N/A
Long-term Debt
N/A

BMEA Revenue & Earnings Growth: 5-Year Financial Trend

BMEA 5-year financial data:
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Biomea Fusion, Inc.'s revenue has remained relatively flat over the 5-year period, with a 0% decline. The most recent EPS of $-3.44 indicates the company is currently unprofitable.

BMEA Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-2,713.7%
Free cash flow / Revenue

BMEA Quarterly Earnings & Performance

Quarterly financial performance data for Biomea Fusion, Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2022 $1.2B -$5.9M $-0.43
Q2 2022 $1.1B -$5.9M N/A
Q1 2022 $1.1B -$5.9M N/A
Q3 2021 $1.1B -$293.0K N/A
Q2 2021 $1.1B -$293.0K N/A
Q1 2021 $1.1B -$398.0K N/A

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Biomea Fusion, Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$11.7M
Cash generated from operations
Dividends
None
No dividend program

BMEA SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Biomea Fusion, Inc. (CIK: 0001840439)

📋 Recent SEC Filings

Date Form Document Action
May 11, 2026 10-Q bmea-20260331.htm View →
May 11, 2026 8-K bmea-20260511.htm View →
Apr 28, 2026 8-K d142809d8k.htm View →
Apr 27, 2026 DEF 14A bmea-20260427.htm View →
Apr 3, 2026 4 xslF345X06/ownership.xml View →

Frequently Asked Questions about BMEA

What is the AI rating for BMEA?

Biomea Fusion, Inc. (BMEA) has a Combined AI Grade of D from Claude (D) and ChatGPT (D) with 82% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are BMEA's key strengths?

Claude: Debt-free balance sheet with zero leverage (Debt/Equity 0.00x). Strong liquidity position (Current Ratio 4.98x) for near-term obligations. ChatGPT: Strong current liquidity with a 3.18x current and quick ratio. No meaningful long-term debt, limiting balance-sheet leverage risk.

What are the risks of investing in BMEA?

Claude: Acute cash burn of $11.7M per quarter with minimal revenue—reserves deplete in 12-15 months. Revenue collapsed 67% YoY to $430K—no evidence of commercial product viability. ChatGPT: Operating and net margins are severely negative, indicating an unsustainable cost structure. Operating cash flow and free cash flow are deeply negative, implying substantial ongoing cash burn.

What is BMEA's revenue and growth?

Biomea Fusion, Inc. reported revenue of $430.0K.

Does BMEA pay dividends?

Biomea Fusion, Inc. does not currently pay dividends.

Where can I find BMEA SEC filings?

Official SEC filings for Biomea Fusion, Inc. (CIK: 0001840439) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is BMEA's EPS?

Biomea Fusion, Inc. has a diluted EPS of $-0.17.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined grade reflects both perspectives for balanced insights.

What is BMEA's fundamental grade?

Based on our AI fundamental analysis in June 2026, Biomea Fusion, Inc. has a D grade with 82% confidence. Review the strengths and risks sections above for full context. This is not investment advice.

Is BMEA stock overvalued or undervalued?

Valuation metrics for BMEA: ROE of -66.3% (sector avg: 15%), net margin of -2,887.2% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

What is BMEA's AI grade for 2026?

Our dual AI analysis gives Biomea Fusion, Inc. a combined D grade for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is BMEA's free cash flow?

Biomea Fusion, Inc.'s operating cash flow is $-11.7M, with capital expenditures of $0.0. FCF margin is -2,713.7%.

How does BMEA compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -2,887.2% (avg: 12%), ROE -66.3% (avg: 15%), current ratio 4.98 (avg: 2).

Top Rated Stocks
AAPL 92% MSFT 92% FAST 92% ANET 88% RDDT 88% KNSL 88% MGRE 88% FIZZ 88% AVGO 87% DECK 87%
Sector: All Healthcare Stocks →
Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: May 12, 2026 | Data as of: 2026-03-31 | Powered by Claude AI