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Biomea Fusion, Inc. (BMEA) Stock Fundamental Analysis & AI Rating 2026

BMEA Nasdaq Pharmaceutical Preparations DE CIK: 0001840439
Updated This Month • Analysis: Mar 21, 2026 • SEC Data: 2025-09-30
Combined AI Rating
STRONG SELL
90% Confidence
STRONG AGREEMENT
STRONG SELL
95% Conf
STRONG SELL
86% Conf

📊 BMEA Key Takeaways

Revenue: $5.4M
Net Margin: -1,233.5%
Free Cash Flow: $-56.4M
Current Ratio: 3.18x
Debt/Equity: 0.00x
EPS: $-1.45
AI Rating: STRONG SELL with 95% confidence
Biomea Fusion, Inc. (BMEA) receives a STRONG SELL rating with 90% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $5.4M, net profit margin of -1,233.5%, and return on equity (ROE) of -425.2%, Biomea Fusion, Inc. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete BMEA stock analysis for 2026.

Is Biomea Fusion, Inc. (BMEA) a Good Investment?

Claude

Biomea Fusion is a pre-revenue stage pharmaceutical company burning significant cash with minimal revenue generation and substantial operating losses. The company faces critical runway constraints despite maintaining a strong cash position, with operating cash burn of -$56.4M annually against only $46.6M in cash reserves.

ChatGPT

Biomea Fusion’s fundamentals are very weak: the company is generating only modest revenue while posting extremely large operating and net losses, with deeply negative margins and returns on capital. Although the balance sheet is not debt-burdened and near-term liquidity is still adequate, the current cash burn appears too high relative to its cash balance, making the business heavily dependent on improving operating performance or raising additional capital.

Why Buy Biomea Fusion, Inc. Stock? BMEA Key Strengths

Claude
  • + Strong liquidity position with $46.6M in cash and 3.18x current ratio
  • + No long-term debt burden providing financial flexibility
  • + Early-stage biotech model with R&D focus appropriate for drug development
ChatGPT
  • + Strong current liquidity with a 3.18x current and quick ratio
  • + No meaningful long-term debt, limiting balance-sheet leverage risk
  • + Cash balances of $46.64M still provide short-term operating flexibility

BMEA Stock Risks: Biomea Fusion, Inc. Investment Risks

Claude
  • ! Severe operating losses of -$71.8M with only $5.4M revenue indicates minimal commercial traction
  • ! Negative free cash flow of -$56.4M annually creates urgent funding need within 12 months
  • ! Extreme negative margins (-1233.5% net margin) indicate business model is not yet viable
  • ! No insider purchases in 90 days suggests lack of management confidence
  • ! High cash burn relative to remaining runway creates existential dilution risk
ChatGPT
  • ! Operating and net margins are severely negative, indicating an unsustainable cost structure
  • ! Operating cash flow and free cash flow are deeply negative, implying substantial ongoing cash burn
  • ! Very low equity base relative to losses raises the risk of future dilution or financial strain

Key Metrics to Watch

Claude
  • * Revenue growth trajectory and clinical trial progress
  • * Monthly cash burn rate and projected runway
  • * Cash position relative to operating expenses
  • * Pipeline advancement and regulatory milestones
  • * Future financing needs and dilution impact
ChatGPT
  • * Quarterly operating cash burn relative to cash and equivalents
  • * Revenue progression versus operating expense growth

Biomea Fusion, Inc. (BMEA) Financial Metrics & Key Ratios

Revenue
$5.4M
Net Income
$-66.4M
EPS (Diluted)
$-1.45
Free Cash Flow
$-56.4M
Total Assets
$55.2M
Cash Position
$46.6M

💡 AI Analyst Insight

Strong liquidity with a 3.18x current ratio provides a solid financial cushion.

BMEA Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin -1,333.5%
Net Margin -1,233.5%
ROE -425.2%
ROA -120.3%
FCF Margin -1,048.1%

BMEA vs Healthcare Sector: How Biomea Fusion, Inc. Compares

How Biomea Fusion, Inc. compares to Healthcare sector averages

Net Margin
BMEA -1,233.5%
vs
Sector Avg 12.0%
BMEA Sector
ROE
BMEA -425.2%
vs
Sector Avg 15.0%
BMEA Sector
Current Ratio
BMEA 3.2x
vs
Sector Avg 2.0x
BMEA Sector
Debt/Equity
BMEA 0.0x
vs
Sector Avg 0.6x
BMEA Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Biomea Fusion, Inc. Stock Overvalued? BMEA Valuation Analysis 2026

Based on fundamental analysis, Biomea Fusion, Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-425.2%
Sector avg: 15%
Net Profit Margin
-1,233.5%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Biomea Fusion, Inc. Balance Sheet: BMEA Debt, Cash & Liquidity

Current Ratio
3.18x
Quick Ratio
3.18x
Debt/Equity
0.00x
Debt/Assets
71.7%
Interest Coverage
N/A
Long-term Debt
N/A

BMEA Revenue & Earnings Growth: 5-Year Financial Trend

BMEA 5-year financial data:
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Biomea Fusion, Inc.'s revenue has remained relatively flat over the 5-year period, with a 0% decline. The most recent EPS of $-3.44 indicates the company is currently unprofitable.

BMEA Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-1,048.1%
Free cash flow / Revenue

BMEA Quarterly Earnings & Performance

Quarterly financial performance data for Biomea Fusion, Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2022 $1.2B -$5.9M $-0.43
Q2 2022 $1.1B -$5.9M N/A
Q1 2022 $1.1B -$5.9M N/A
Q3 2021 $1.1B -$293.0K N/A
Q2 2021 $1.1B -$293.0K N/A
Q1 2021 $1.1B -$398.0K N/A

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Biomea Fusion, Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$56.4M
Cash generated from operations
Dividends
None
No dividend program

BMEA SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Biomea Fusion, Inc. (CIK: 0001840439)

📋 Recent SEC Filings

Date Form Document Action
Apr 3, 2026 4 xslF345X06/ownership.xml View →
Apr 3, 2026 4 xslF345X06/ownership.xml View →
Mar 24, 2026 10-K bmea-20251231.htm View →
Mar 24, 2026 8-K bmea-20260324.htm View →
Feb 25, 2026 8-K d95198d8k.htm View →

Frequently Asked Questions about BMEA

What is the AI rating for BMEA?

Biomea Fusion, Inc. (BMEA) has a Combined AI Rating of STRONG SELL from Claude (STRONG SELL) and ChatGPT (STRONG SELL) with 90% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are BMEA's key strengths?

Claude: Strong liquidity position with $46.6M in cash and 3.18x current ratio. No long-term debt burden providing financial flexibility. ChatGPT: Strong current liquidity with a 3.18x current and quick ratio. No meaningful long-term debt, limiting balance-sheet leverage risk.

What are the risks of investing in BMEA?

Claude: Severe operating losses of -$71.8M with only $5.4M revenue indicates minimal commercial traction. Negative free cash flow of -$56.4M annually creates urgent funding need within 12 months. ChatGPT: Operating and net margins are severely negative, indicating an unsustainable cost structure. Operating cash flow and free cash flow are deeply negative, implying substantial ongoing cash burn.

What is BMEA's revenue and growth?

Biomea Fusion, Inc. reported revenue of $5.4M.

Does BMEA pay dividends?

Biomea Fusion, Inc. does not currently pay dividends.

Where can I find BMEA SEC filings?

Official SEC filings for Biomea Fusion, Inc. (CIK: 0001840439) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is BMEA's EPS?

Biomea Fusion, Inc. has a diluted EPS of $-1.45.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is BMEA a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Biomea Fusion, Inc. has a STRONG SELL rating with 90% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is BMEA stock overvalued or undervalued?

Valuation metrics for BMEA: ROE of -425.2% (sector avg: 15%), net margin of -1,233.5% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy BMEA stock in 2026?

Our dual AI analysis gives Biomea Fusion, Inc. a combined STRONG SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is BMEA's free cash flow?

Biomea Fusion, Inc.'s operating cash flow is $-56.4M, with capital expenditures of $0.0. FCF margin is -1,048.1%.

How does BMEA compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -1,233.5% (avg: 12%), ROE -425.2% (avg: 15%), current ratio 3.18 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Mar 21, 2026 | Data as of: 2025-09-30 | Powered by Claude AI