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Biofrontera Inc. (BFRIW) Stock Fundamental Analysis & AI Rating 2026

BFRIW Nasdaq Pharmaceutical Preparations DE CIK: 0001858685
Updated This Month • Analysis: Mar 20, 2026 • SEC Data: 2025-12-31
Combined AI Rating
SELL
84% Confidence
STRONG AGREEMENT
SELL
85% Conf
SELL
82% Conf

📊 BFRIW Key Takeaways

Revenue: $41.7M
Net Margin: -25.3%
Free Cash Flow: $-13.4M
Current Ratio: 1.52x
Debt/Equity: 0.00x
EPS: $-1.04
AI Rating: SELL with 85% confidence
Biofrontera Inc. (BFRIW) receives a SELL rating with 84% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $41.7M, net profit margin of -25.3%, and return on equity (ROE) of -100.5%, Biofrontera Inc. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete BFRIW stock analysis for 2026.

Is Biofrontera Inc. (BFRIW) a Good Investment?

Claude

Biofrontera demonstrates deteriorating fundamental health despite modest revenue growth. Severe cash burn of $13.4M annually combined with negative profitability across all metrics suggests the company is consuming capital at an unsustainable rate. With only $6.4M in cash and negative operating cash flow, the company faces significant liquidity pressure without a clear path to profitability.

ChatGPT

Biofrontera shows some top-line momentum and materially improved net losses, but the core business remains structurally unprofitable with deeply negative operating margins and cash flow. The balance sheet is helped by no meaningful debt and acceptable near-term liquidity, yet the current cash position looks thin relative to ongoing operating cash burn, which weakens the quality of the growth story.

Why Buy Biofrontera Inc. Stock? BFRIW Key Strengths

Claude
  • + Revenue growth of 11.7% year-over-year shows top-line expansion
  • + Positive cash position of $6.4M provides some operational runway
  • + Low leverage with 0.00x debt-to-equity ratio reduces financial stress
ChatGPT
  • + Revenue grew 11.7% year over year, indicating continued commercial traction
  • + Net loss and diluted EPS improved meaningfully versus the prior year
  • + Balance sheet leverage is low, with 0.00x debt-to-equity and a 1.52x current ratio

BFRIW Stock Risks: Biofrontera Inc. Investment Risks

Claude
  • ! Severe cash burn of $13.4M annually with only 5.7 months of runway at current burn rate
  • ! Consistently negative profitability with -25.3% net margin and -27.2% operating margin
  • ! Operating cash flow of -$13.4M indicates core business cannot fund operations
  • ! Negative ROE of -100.5% and ROA of -36.9% demonstrate capital destruction
  • ! Free cash flow margin of -32.0% indicates value destruction on every dollar of revenue
ChatGPT
  • ! Operating margin of -27.2% and net margin of -25.3% show the business is still far from sustainable profitability
  • ! Operating cash flow and free cash flow were both -$13.36M, indicating heavy ongoing cash burn
  • ! Cash of $6.39M appears limited relative to annual cash outflows, raising funding and dilution risk if trends do not improve

Key Metrics to Watch

Claude
  • * Operating cash flow trend and path to positive FCF
  • * Monthly cash burn rate and cash runway remaining
  • * Revenue growth sustainability and gross margin if disclosed
  • * Operating leverage improvements and timeline to EBITDA profitability
ChatGPT
  • * Operating cash flow burn relative to cash balance
  • * Operating margin improvement alongside revenue growth

Biofrontera Inc. (BFRIW) Financial Metrics & Key Ratios

Revenue
$41.7M
Net Income
$-10.5M
EPS (Diluted)
$-1.04
Free Cash Flow
$-13.4M
Total Assets
$28.6M
Cash Position
$6.4M

💡 AI Analyst Insight

Biofrontera Inc. presents a mixed fundamental picture. Review the detailed metrics above to form your own investment thesis.

BFRIW Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin -27.2%
Net Margin -25.3%
ROE -100.5%
ROA -36.9%
FCF Margin -32.0%

BFRIW vs Healthcare Sector: How Biofrontera Inc. Compares

How Biofrontera Inc. compares to Healthcare sector averages

Net Margin
BFRIW -25.3%
vs
Sector Avg 12.0%
BFRIW Sector
ROE
BFRIW -100.5%
vs
Sector Avg 15.0%
BFRIW Sector
Current Ratio
BFRIW 1.5x
vs
Sector Avg 2.0x
BFRIW Sector
Debt/Equity
BFRIW 0.0x
vs
Sector Avg 0.6x
BFRIW Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Biofrontera Inc. Stock Overvalued? BFRIW Valuation Analysis 2026

Based on fundamental analysis, Biofrontera Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-100.5%
Sector avg: 15%
Net Profit Margin
-25.3%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Biofrontera Inc. Balance Sheet: BFRIW Debt, Cash & Liquidity

Current Ratio
1.52x
Quick Ratio
1.40x
Debt/Equity
0.00x
Debt/Assets
63.3%
Interest Coverage
-5.56x
Long-term Debt
N/A

BFRIW Revenue & Earnings Growth: 5-Year Financial Trend

BFRIW 5-year financial data: Year 2021: Revenue $24.1M, Net Income -$11.0M, EPS N/A. Year 2022: Revenue $28.7M, Net Income -$37.7M, EPS N/A. Year 2023: Revenue $34.1M, Net Income -$640.0K, EPS $-0.61. Year 2024: Revenue $37.3M, Net Income -$20.1M, EPS $-13.02. Year 2025: Revenue $41.7M, Net Income -$17.8M, EPS $-3.22.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Biofrontera Inc.'s revenue has grown significantly by 73% over the 5-year period, indicating strong business expansion. The most recent EPS of $-3.22 indicates the company is currently unprofitable.

BFRIW Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-32.0%
Free cash flow / Revenue

BFRIW Quarterly Earnings & Performance

Quarterly financial performance data for Biofrontera Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 $7.0M -$5.7M $-0.62
Q2 2025 $7.8M -$257.0K $-0.05
Q1 2025 $7.9M -$4.2M $-0.47
Q3 2024 $8.9M -$5.7M $-0.98
Q2 2024 $5.8M -$257.0K $-0.05
Q1 2024 $7.9M -$7.5M $-2.88
Q3 2023 $4.3M $2.1M $2.19
Q2 2023 $4.5M -$850.0K $-0.90

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Biofrontera Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$13.4M
Cash generated from operations
Capital Expenditures
$2.0K
Investment in assets
Dividends
None
No dividend program

BFRIW SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Biofrontera Inc. (CIK: 0001858685)

📋 Recent SEC Filings

Date Form Document Action
Mar 19, 2026 10-K form10-k.htm View →
Mar 19, 2026 8-K form8-k.htm View →
Mar 9, 2026 8-K form8-k.htm View →
Mar 6, 2026 4 xslF345X05/ownership.xml View →
Mar 6, 2026 4 xslF345X05/ownership.xml View →

Frequently Asked Questions about BFRIW

What is the AI rating for BFRIW?

Biofrontera Inc. (BFRIW) has a Combined AI Rating of SELL from Claude (SELL) and ChatGPT (SELL) with 84% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are BFRIW's key strengths?

Claude: Revenue growth of 11.7% year-over-year shows top-line expansion. Positive cash position of $6.4M provides some operational runway. ChatGPT: Revenue grew 11.7% year over year, indicating continued commercial traction. Net loss and diluted EPS improved meaningfully versus the prior year.

What are the risks of investing in BFRIW?

Claude: Severe cash burn of $13.4M annually with only 5.7 months of runway at current burn rate. Consistently negative profitability with -25.3% net margin and -27.2% operating margin. ChatGPT: Operating margin of -27.2% and net margin of -25.3% show the business is still far from sustainable profitability. Operating cash flow and free cash flow were both -$13.36M, indicating heavy ongoing cash burn.

What is BFRIW's revenue and growth?

Biofrontera Inc. reported revenue of $41.7M.

Does BFRIW pay dividends?

Biofrontera Inc. does not currently pay dividends.

Where can I find BFRIW SEC filings?

Official SEC filings for Biofrontera Inc. (CIK: 0001858685) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is BFRIW's EPS?

Biofrontera Inc. has a diluted EPS of $-1.04.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is BFRIW a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Biofrontera Inc. has a SELL rating with 84% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is BFRIW stock overvalued or undervalued?

Valuation metrics for BFRIW: ROE of -100.5% (sector avg: 15%), net margin of -25.3% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy BFRIW stock in 2026?

Our dual AI analysis gives Biofrontera Inc. a combined SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is BFRIW's free cash flow?

Biofrontera Inc.'s operating cash flow is $-13.4M, with capital expenditures of $2.0K. FCF margin is -32.0%.

How does BFRIW compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -25.3% (avg: 12%), ROE -100.5% (avg: 15%), current ratio 1.52 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Mar 20, 2026 | Data as of: 2025-12-31 | Powered by Claude AI