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Arrowhead Pharmaceuticals, Inc.. (ARWR) Stock Fundamental Analysis & AI Rating 2026

ARWR Nasdaq Pharmaceutical Preparations DE CIK: 0000879407
Updated This Month • Analysis: Mar 20, 2026 • SEC Data: 2025-12-31
Combined AI Rating
HOLD
68% Confidence
STRONG AGREEMENT
HOLD
62% Conf
HOLD
74% Conf

📊 ARWR Key Takeaways

Revenue: $264.0M
Net Margin: 11.7%
Free Cash Flow: $11.3M
Current Ratio: 3.38x
Debt/Equity: 0.00x
EPS: $0.22
AI Rating: HOLD with 62% confidence
Arrowhead Pharmaceuticals, Inc.. (ARWR) receives a HOLD rating with 68% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $264.0M, net profit margin of 11.7%, and return on equity (ROE) of 5.4%, Arrowhead Pharmaceuticals, Inc.. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete ARWR stock analysis for 2026.

Is Arrowhead Pharmaceuticals, Inc.. (ARWR) a Good Investment?

Claude

Arrowhead Pharmaceuticals demonstrates exceptional revenue growth (+23258% YoY) with positive net income of $30.8M and strong liquidity (3.38x current ratio), indicating successful commercialization or major milestone. However, the dramatic YoY revenue surge masks concerning operational efficiency issues, with net income declining 105.4% YoY despite higher revenues, and weak free cash flow conversion (4.3% FCF margin) suggests cash generation challenges.

ChatGPT

Arrowhead Pharmaceuticals shows a materially improved near-term fundamental profile, with sharp revenue growth, positive operating income, and positive free cash flow alongside a very strong liquidity position and minimal leverage. However, growth quality appears uneven because profitability conversion remains modest relative to the revenue spike, returns on assets and equity are still low, and the reported revenue surge may reflect lumpier biotech economics rather than a fully durable operating trend.

Why Buy Arrowhead Pharmaceuticals, Inc.. Stock? ARWR Key Strengths

Claude
  • + Exceptional revenue growth of 23,258% YoY indicating major commercial breakthrough or significant milestone achievement
  • + Strong balance sheet with $201.6M cash, minimal debt ($1.0M long-term), and 0.00x debt-to-equity ratio providing financial flexibility
  • + Robust liquidity position with 3.38x current and quick ratios, indicating strong ability to meet short-term obligations
  • + Positive operating margin of 15.5% and net margin of 11.7% demonstrating profitability in latest period
ChatGPT
  • + Strong liquidity with 3.38x current and quick ratios plus over $200M in cash
  • + Near-zero leverage with only about $1M in long-term debt, limiting balance-sheet risk
  • + Positive operating income, net income, and free cash flow indicate improved near-term operating performance

ARWR Stock Risks: Arrowhead Pharmaceuticals, Inc.. Investment Risks

Claude
  • ! Net income declined 105.4% YoY despite massive revenue growth, signaling deteriorating operational leverage and cost control issues
  • ! Very weak free cash flow margin of 4.3% indicates majority of revenue is not converting to cash, raising sustainability concerns
  • ! Extremely volatile YoY comparisons suggest potential one-time revenue event, milestone payment, or accounting treatment change rather than sustainable business momentum
  • ! Low ROE of 5.4% and ROA of 1.9% indicate inefficient asset utilization and poor returns on shareholder capital
  • ! Operating cash flow of only $13.5M against $264M revenue suggests significant working capital management issues or non-cash revenue recognition
ChatGPT
  • ! Revenue growth may be low quality or non-recurring given the extreme YoY spike typical of milestone-driven biotech revenue
  • ! Profitability remains fragile with only 11.7% net margin, 4.3% FCF margin, and 3.2x interest coverage
  • ! Low ROA and ROE suggest the company is not yet generating strong returns from its asset and equity base

Key Metrics to Watch

Claude
  • * Recurring revenue quality and sustainability - determine if 23,258% growth reflects genuine ongoing business or one-time milestone
  • * Free cash flow conversion and operating cash flow trend - critical to assess if company can sustain operations and fund R&D
  • * Gross margin when disclosed - currently unavailable but essential to understand product profitability and manufacturing efficiency
  • * R&D spending levels and pipeline progress - crucial for pharmaceutical company to justify investment thesis
  • * Debt trajectory and covenant compliance - monitor for potential dilution or financing needs given weak cash generation
ChatGPT
  • * Operating cash flow and free cash flow consistency
  • * Revenue durability and operating margin sustainability

Arrowhead Pharmaceuticals, Inc.. (ARWR) Financial Metrics & Key Ratios

Revenue
$264.0M
Net Income
$30.8M
EPS (Diluted)
$0.22
Free Cash Flow
$11.3M
Total Assets
$1.6B
Cash Position
$201.6M

💡 AI Analyst Insight

The relatively thin 4.3% FCF margin may limit capital allocation flexibility. Strong liquidity with a 3.38x current ratio provides a solid financial cushion.

ARWR Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin 15.5%
Net Margin 11.7%
ROE 5.4%
ROA 1.9%
FCF Margin 4.3%

ARWR vs Healthcare Sector: How Arrowhead Pharmaceuticals, Inc.. Compares

How Arrowhead Pharmaceuticals, Inc.. compares to Healthcare sector averages

Net Margin
ARWR 11.7%
vs
Sector Avg 12.0%
ARWR Sector
ROE
ARWR 5.4%
vs
Sector Avg 15.0%
ARWR Sector
Current Ratio
ARWR 3.4x
vs
Sector Avg 2.0x
ARWR Sector
Debt/Equity
ARWR 0.0x
vs
Sector Avg 0.6x
ARWR Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Arrowhead Pharmaceuticals, Inc.. Stock Overvalued? ARWR Valuation Analysis 2026

Based on fundamental analysis, Arrowhead Pharmaceuticals, Inc.. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
5.4%
Sector avg: 15%
Net Profit Margin
11.7%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Arrowhead Pharmaceuticals, Inc.. Balance Sheet: ARWR Debt, Cash & Liquidity

Current Ratio
3.38x
Quick Ratio
3.38x
Debt/Equity
0.00x
Debt/Assets
0.0%
Interest Coverage
3.24x
Long-term Debt
$1.0M

ARWR Revenue & Earnings Growth: 5-Year Financial Trend

ARWR 5-year financial data: Year 2021: Revenue $168.8M, Net Income $68.0M, EPS $0.69. Year 2022: Revenue $243.2M, Net Income -$84.6M, EPS $-0.84. Year 2023: Revenue $243.2M, Net Income -$140.8M, EPS $-1.36. Year 2024: Revenue $243.2M, Net Income -$176.1M, EPS $-1.67. Year 2025: Revenue $829.4M, Net Income -$205.3M, EPS $-1.92.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Arrowhead Pharmaceuticals, Inc..'s revenue has grown significantly by 391% over the 5-year period, indicating strong business expansion. The most recent EPS of $-1.92 indicates the company is currently unprofitable.

ARWR Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
4.3%
Free cash flow / Revenue

ARWR Quarterly Earnings & Performance

Quarterly financial performance data for Arrowhead Pharmaceuticals, Inc.. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q1 2026 $2.5M $30.8M $0.22
Q3 2025 N/A $22.1M $0.17
Q2 2025 N/A -$125.3M $-1.02
Q1 2025 $2.5M -$132.9M $-1.24
Q3 2024 N/A -$95.6M $-0.90
Q2 2024 N/A $7.4M $0.07
Q1 2024 $3.6M -$41.3M $-0.39
Q3 2023 $15.8M -$41.3M $-0.68

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Arrowhead Pharmaceuticals, Inc.. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
$13.5M
Cash generated from operations
Capital Expenditures
$2.1M
Investment in assets
Dividends
None
No dividend program

ARWR SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Arrowhead Pharmaceuticals, Inc.. (CIK: 0000879407)

📋 Recent SEC Filings

Date Form Document Action
Mar 20, 2026 8-K arwr-20260319.htm View →
Mar 9, 2026 4 xslF345X05/wk-form4_1773097203.xml View →
Feb 5, 2026 10-Q arwr-20251231.htm View →
Feb 5, 2026 8-K arwr-20260205.htm View →
Jan 27, 2026 DEF 14A arwr-20260126.htm View →

Frequently Asked Questions about ARWR

What is the AI rating for ARWR?

Arrowhead Pharmaceuticals, Inc.. (ARWR) has a Combined AI Rating of HOLD from Claude (HOLD) and ChatGPT (HOLD) with 68% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are ARWR's key strengths?

Claude: Exceptional revenue growth of 23,258% YoY indicating major commercial breakthrough or significant milestone achievement. Strong balance sheet with $201.6M cash, minimal debt ($1.0M long-term), and 0.00x debt-to-equity ratio providing financial flexibility. ChatGPT: Strong liquidity with 3.38x current and quick ratios plus over $200M in cash. Near-zero leverage with only about $1M in long-term debt, limiting balance-sheet risk.

What are the risks of investing in ARWR?

Claude: Net income declined 105.4% YoY despite massive revenue growth, signaling deteriorating operational leverage and cost control issues. Very weak free cash flow margin of 4.3% indicates majority of revenue is not converting to cash, raising sustainability concerns. ChatGPT: Revenue growth may be low quality or non-recurring given the extreme YoY spike typical of milestone-driven biotech revenue. Profitability remains fragile with only 11.7% net margin, 4.3% FCF margin, and 3.2x interest coverage.

What is ARWR's revenue and growth?

Arrowhead Pharmaceuticals, Inc.. reported revenue of $264.0M.

Does ARWR pay dividends?

Arrowhead Pharmaceuticals, Inc.. does not currently pay dividends.

Where can I find ARWR SEC filings?

Official SEC filings for Arrowhead Pharmaceuticals, Inc.. (CIK: 0000879407) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is ARWR's EPS?

Arrowhead Pharmaceuticals, Inc.. has a diluted EPS of $0.22.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is ARWR a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Arrowhead Pharmaceuticals, Inc.. has a HOLD rating with 68% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is ARWR stock overvalued or undervalued?

Valuation metrics for ARWR: ROE of 5.4% (sector avg: 15%), net margin of 11.7% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy ARWR stock in 2026?

Our dual AI analysis gives Arrowhead Pharmaceuticals, Inc.. a combined HOLD rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is ARWR's free cash flow?

Arrowhead Pharmaceuticals, Inc..'s operating cash flow is $13.5M, with capital expenditures of $2.1M. FCF margin is 4.3%.

How does ARWR compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin 11.7% (avg: 12%), ROE 5.4% (avg: 15%), current ratio 3.38 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Mar 20, 2026 | Data as of: 2025-12-31 | Powered by Claude AI