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Arcturus Therapeutics Holdings Inc. (ARCT) Fundamental Analysis & AI Grade 2026

ARCT Nasdaq Pharmaceutical Preparations DE CIK: 0001768224
Update Pending • Analysis: May 9, 2026 • SEC Data: 2026-03-31
Combined AI Grade
C
76% Confidence
AGREEMENT
C
78% Conf
B
74% Conf

📊 ARCT Key Takeaways

Revenue: $2.1M
Net Margin: -1,308.3%
Free Cash Flow: $-19.4M
Current Ratio: 6.31x
Debt/Equity: 0.08x
EPS: $-0.95
AI Grade: C with 78% confidence
Arcturus Therapeutics Holdings Inc. (ARCT) receives a C fundamental grade with 76% confidence from our AI analysis based on SEC 10-K filings. With revenue of $2.1M, net profit margin of -1,308.3%, and return on equity (ROE) of -14.1%, Arcturus Therapeutics Holdings Inc. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete ARCT stock analysis for 2026.

Is Arcturus Therapeutics Holdings Inc. (ARCT) a Good Investment?

Claude

Arcturus Therapeutics is a development-stage biotech facing severe operational challenges with revenue collapsing 46% YoY to just $2.1M, while burning $28.9M in operating losses. The company maintains adequate liquidity with $211.4M cash reserves, but lacks a demonstrated path to profitability or revenue recovery, making it fundamentally distressed despite balance sheet strength.

ChatGPT

Arcturus Therapeutics has weak current fundamentals, with revenue down 46.1% year over year, deeply negative operating margin, and substantial cash burn. However, the balance sheet is unusually strong for a loss-making biotech, with $230.91M in cash, low leverage, and solid liquidity that provide meaningful operating runway while management works toward more durable revenue generation and improved operating efficiency.

Arcturus Therapeutics Holdings Inc. Key Strengths (ARCT)

Claude
  • + Strong cash position of $211.4M provides 10+ year operating runway at current burn rate
  • + Minimal leverage with debt-to-equity of 0.08x and only $15.0M long-term debt
  • + Excellent liquidity with current ratio of 6.31x, reducing near-term bankruptcy risk
ChatGPT
  • + Very strong liquidity, with a 6.64x current and quick ratio supported by $230.91M in cash
  • + Low balance-sheet leverage, with debt-to-equity of just 0.07x and only $15.00M in long-term debt
  • + Net loss and diluted EPS improved year over year despite continued operating pressure

ARCT Stock Risks: Arcturus Therapeutics Holdings Inc. Investment Risks

Claude
  • ! Revenue collapse of 46% YoY to critically low $2.1M indicates severe business deterioration
  • ! Massive operating losses of $28.9M with negative operating margin of -1403.7% showing unsustainable unit economics
  • ! Negative operating and free cash flow of -$19.4M annually means cash reserves are only buffer, not sustainable model
  • ! No visible path to profitability or revenue growth despite existing product/asset portfolio
ChatGPT
  • ! Revenue fell 46.1% year over year, indicating weak growth quality and likely dependence on lumpy or non-recurring revenue sources
  • ! Core profitability remains poor, with a -93.0% operating margin and -80.2% net margin
  • ! Free cash flow was -$74.50M, so sustained cash burn could materially reduce financial flexibility if revenue does not recover

Key Metrics to Watch

Claude
  • * Revenue growth rate and ability to stabilize/reverse 46% decline
  • * Operating cash flow trajectory and timeline to positive cash generation
  • * Cash burn rate relative to remaining reserves and runway
  • * FDA approvals or clinical trial results that could restore revenue streams
ChatGPT
  • * Quarterly revenue consistency and whether top-line growth becomes recurring rather than episodic
  • * Operating cash burn and free cash flow relative to the current cash balance

Arcturus Therapeutics Holdings Inc. (ARCT) Financial Metrics & Key Ratios

Revenue
$2.1M
Net Income
$-27.0M
EPS (Diluted)
$-0.95
Free Cash Flow
$-19.4M
Total Assets
$245.4M
Cash Position
$211.4M

💡 AI Analyst Insight

Strong liquidity with a 6.31x current ratio provides a solid financial cushion.

ARCT Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin -1,403.7%
Net Margin -1,308.3%
ROE -14.1%
ROA -11.0%
FCF Margin -943.3%

ARCT vs Healthcare Sector: How Arcturus Therapeutics Holdings Inc. Compares

How Arcturus Therapeutics Holdings Inc. compares to Healthcare sector averages

Net Margin
ARCT -1,308.3%
vs
Sector Avg 12.0%
ARCT Sector
ROE
ARCT -14.1%
vs
Sector Avg 15.0%
ARCT Sector
Current Ratio
ARCT 6.3x
vs
Sector Avg 2.0x
ARCT Sector
Debt/Equity
ARCT 0.1x
vs
Sector Avg 0.6x
ARCT Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Arcturus Therapeutics Holdings Inc. Stock Overvalued? ARCT Valuation Analysis 2026

Based on fundamental analysis, Arcturus Therapeutics Holdings Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-14.1%
Sector avg: 15%
Net Profit Margin
-1,308.3%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.08x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Arcturus Therapeutics Holdings Inc. Balance Sheet: ARCT Debt, Cash & Liquidity

Current Ratio
6.31x
Quick Ratio
6.31x
Debt/Equity
0.08x
Debt/Assets
22.0%
Interest Coverage
N/A
Long-term Debt
$15.0M

ARCT Revenue & Earnings Growth: 5-Year Financial Trend

ARCT 5-year financial data: Year 2021: Revenue $20.8M, Net Income -$26.0M, EPS N/A. Year 2022: Revenue $206.0M, Net Income -$203.7M, EPS $-7.74. Year 2023: Revenue $206.0M, Net Income -$203.7M, EPS $-7.74. Year 2024: Revenue $206.0M, Net Income $9.3M, EPS $0.35. Year 2025: Revenue $166.8M, Net Income -$29.7M, EPS $-1.12.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Arcturus Therapeutics Holdings Inc.'s revenue has grown significantly by 702% over the 5-year period, indicating strong business expansion. The most recent EPS of $-1.12 indicates the company is currently unprofitable.

ARCT Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-943.3%
Free cash flow / Revenue

ARCT Quarterly Earnings & Performance

Quarterly financial performance data for Arcturus Therapeutics Holdings Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q1 2026 $2.1M -$14.1M $-0.52
Q3 2025 $17.2M -$6.9M $-0.26
Q2 2025 $28.3M -$9.2M $-0.34
Q1 2025 $29.4M -$14.1M $-0.52
Q3 2024 $41.7M -$6.9M $-0.26
Q2 2024 $10.5M -$1.8M $-0.07
Q1 2024 $38.0M -$26.8M $-1.00
Q3 2023 $13.4M -$16.2M $-0.61

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Arcturus Therapeutics Holdings Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$19.4M
Cash generated from operations
Dividends
None
No dividend program

ARCT SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Arcturus Therapeutics Holdings Inc. (CIK: 0001768224)

📋 Recent SEC Filings

Date Form Document Action
Jun 5, 2026 8-K e665552_8k-arct.htm View →
May 7, 2026 4 xslF345X06/e665445_4-mulroy.xml View →
May 7, 2026 10-Q arct-20260331.htm View →
May 7, 2026 8-K e665435_8k-arct.htm View →
Apr 24, 2026 DEF 14A e665392_def14a-arct.htm View →

Frequently Asked Questions about ARCT

What is the AI rating for ARCT?

Arcturus Therapeutics Holdings Inc. (ARCT) has a Combined AI Grade of C from Claude (C) and ChatGPT (B) with 76% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are ARCT's key strengths?

Claude: Strong cash position of $211.4M provides 10+ year operating runway at current burn rate. Minimal leverage with debt-to-equity of 0.08x and only $15.0M long-term debt. ChatGPT: Very strong liquidity, with a 6.64x current and quick ratio supported by $230.91M in cash. Low balance-sheet leverage, with debt-to-equity of just 0.07x and only $15.00M in long-term debt.

What are the risks of investing in ARCT?

Claude: Revenue collapse of 46% YoY to critically low $2.1M indicates severe business deterioration. Massive operating losses of $28.9M with negative operating margin of -1403.7% showing unsustainable unit economics. ChatGPT: Revenue fell 46.1% year over year, indicating weak growth quality and likely dependence on lumpy or non-recurring revenue sources. Core profitability remains poor, with a -93.0% operating margin and -80.2% net margin.

What is ARCT's revenue and growth?

Arcturus Therapeutics Holdings Inc. reported revenue of $2.1M.

Does ARCT pay dividends?

Arcturus Therapeutics Holdings Inc. does not currently pay dividends.

Where can I find ARCT SEC filings?

Official SEC filings for Arcturus Therapeutics Holdings Inc. (CIK: 0001768224) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is ARCT's EPS?

Arcturus Therapeutics Holdings Inc. has a diluted EPS of $-0.95.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined grade reflects both perspectives for balanced insights.

What is ARCT's fundamental grade?

Based on our AI fundamental analysis in June 2026, Arcturus Therapeutics Holdings Inc. has a C grade with 76% confidence. Review the strengths and risks sections above for full context. This is not investment advice.

Is ARCT stock overvalued or undervalued?

Valuation metrics for ARCT: ROE of -14.1% (sector avg: 15%), net margin of -1,308.3% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

What is ARCT's AI grade for 2026?

Our dual AI analysis gives Arcturus Therapeutics Holdings Inc. a combined C grade for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is ARCT's free cash flow?

Arcturus Therapeutics Holdings Inc.'s operating cash flow is $-19.4M, with capital expenditures of $0.0. FCF margin is -943.3%.

How does ARCT compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -1,308.3% (avg: 12%), ROE -14.1% (avg: 15%), current ratio 6.31 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: May 9, 2026 | Data as of: 2026-03-31 | Powered by Claude AI