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Alumis Inc.. (ALMS) Fundamental Analysis & AI Grade 2026

ALMS Nasdaq Pharmaceutical Preparations DE CIK: 0001847367
Updated This Month • Analysis: May 15, 2026 • SEC Data: 2026-03-31
Combined AI Grade
C
66% Confidence
STRONG AGREEMENT
C
45% Conf
C
88% Conf

📊 ALMS Key Takeaways

Revenue: $1.7M
Net Margin: -5,344.8%
Free Cash Flow: $-87.2M
Current Ratio: 7.51x
Debt/Equity: 0.00x
EPS: $-0.74
AI Grade: C with 45% confidence
Alumis Inc.. (ALMS) receives a C fundamental grade with 66% confidence from our AI analysis based on SEC 10-K filings. With revenue of $1.7M, net profit margin of -5,344.8%, and return on equity (ROE) of -16.4%, Alumis Inc.. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete ALMS stock analysis for 2026.

Is Alumis Inc.. (ALMS) a Good Investment?

Claude

ALUMIS is an early-stage pharmaceutical company with minimal revenue ($1.7M) and massive operating losses (-$98.4M), coupled with negative operating cash flow of -$87.1M. While the strong balance sheet ($567M equity, $63.9M cash) provides operational runway of 1-2 years, the company lacks demonstrated profitability or clear revenue trajectory from available fundamentals.

ChatGPT

Alumis shows extremely weak current fundamentals, with minimal revenue relative to its cost base, deeply negative operating and net margins, and nearly $300M of annual free cash outflow. The balance sheet is a mitigating factor because liquidity is strong and leverage is negligible, but the business still depends on translating pipeline spending into durable revenue before cash burn materially erodes that cushion.

Alumis Inc.. Key Strengths (ALMS)

Claude
  • + Strong balance sheet with $567M stockholders' equity and effectively zero debt
  • + Substantial cash reserves of $63.9M providing runway for continued R&D operations
  • + Excellent liquidity position with 7.51x current ratio limiting near-term financial distress risk
ChatGPT
  • + Strong liquidity with a 6.01x current ratio and meaningful cash relative to liabilities
  • + No meaningful balance-sheet leverage, reducing refinancing and solvency pressure
  • + Positive reported revenue indicates at least some non-zero commercial or collaboration inflow

ALMS Stock Risks: Alumis Inc.. Investment Risks

Claude
  • ! Massive operating losses of -$98.4M against only $1.7M revenue indicates unsustainable burn rate unsupported by revenue
  • ! Negative operating cash flow of -$87.1M will deplete reserves within 12-18 months if business model does not change
  • ! No demonstrated commercialization path or profitability timeline visible from available financial data; company appears in early R&D phase with unproven pipeline
ChatGPT
  • ! Operating model is highly unprofitable, with operating margin of -1615.5% and net margin of -679.9%
  • ! Cash burn is severe, with operating cash flow of -$297.62M and free cash flow of -$298.27M
  • ! Growth quality is weak because revenue remains far too small to support the current expense base

Key Metrics to Watch

Claude
  • * Quarterly revenue growth and clinical trial progression for lead pipeline candidates
  • * Monthly operating cash burn rate and projected runway remaining
  • * Gross margin evolution as company transitions from R&D to commercialization phase
ChatGPT
  • * Quarterly operating cash burn versus cash and equivalents
  • * Revenue scale-up and operating expense discipline

Alumis Inc.. (ALMS) Financial Metrics & Key Ratios

Revenue
$1.7M
Net Income
$-93.1M
EPS (Diluted)
$-0.74
Free Cash Flow
$-87.2M
Total Assets
$671.6M
Cash Position
$63.9M

💡 AI Analyst Insight

Strong liquidity with a 7.51x current ratio provides a solid financial cushion.

ALMS Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin -5,652.4%
Net Margin -5,344.8%
ROE -16.4%
ROA -13.9%
FCF Margin -5,011.3%

ALMS vs Healthcare Sector: How Alumis Inc.. Compares

How Alumis Inc.. compares to Healthcare sector averages

Net Margin
ALMS -5,344.8%
vs
Sector Avg 12.0%
ALMS Sector
ROE
ALMS -16.4%
vs
Sector Avg 15.0%
ALMS Sector
Current Ratio
ALMS 7.5x
vs
Sector Avg 2.0x
ALMS Sector
Debt/Equity
ALMS 0.0x
vs
Sector Avg 0.6x
ALMS Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Alumis Inc.. Stock Overvalued? ALMS Valuation Analysis 2026

Based on fundamental analysis, Alumis Inc.. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-16.4%
Sector avg: 15%
Net Profit Margin
-5,344.8%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Alumis Inc.. Balance Sheet: ALMS Debt, Cash & Liquidity

Current Ratio
7.51x
Quick Ratio
7.51x
Debt/Equity
0.00x
Debt/Assets
15.6%
Interest Coverage
N/A
Long-term Debt
N/A

ALMS Revenue & Earnings Growth: 5-Year Financial Trend

ALMS 5-year financial data: Year 2025: Revenue $24.1M, Net Income -$294.2M, EPS $-10.38.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Alumis Inc..'s revenue has remained relatively flat over the 5-year period, with a 0% decline. The most recent EPS of $-10.38 indicates the company is currently unprofitable.

ALMS Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-5,011.3%
Free cash flow / Revenue

ALMS Quarterly Earnings & Performance

Quarterly financial performance data for Alumis Inc.. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q1 2026 $1.7M -$93.1M $-0.74
Q3 2025 $2.1M -$49.8M $-1.06
Q2 2025 $2.7M -$39.6M $-0.61
Q1 2025 $17.4M -$49.8M $-1.82

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Alumis Inc.. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$87.1M
Cash generated from operations
Stock Buybacks
$17.0K
Shares repurchased (TTM)
Capital Expenditures
$164.0K
Investment in assets
Dividends
None
No dividend program

ALMS SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Alumis Inc.. (CIK: 0001847367)

📋 Recent SEC Filings

Date Form Document Action
May 27, 2026 4 xslF345X06/form4-05272026_110540.xml View →
May 18, 2026 DEF 14A tm266546-1_def14a.htm View →
May 14, 2026 10-Q alms-20260331x10q.htm View →
May 14, 2026 8-K alms-20260514x8k.htm View →
Apr 3, 2026 4 xslF345X06/tm2611109-3_4seq1.xml View →

Frequently Asked Questions about ALMS

What is the AI rating for ALMS?

Alumis Inc.. (ALMS) has a Combined AI Grade of C from Claude (C) and ChatGPT (C) with 66% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are ALMS's key strengths?

Claude: Strong balance sheet with $567M stockholders' equity and effectively zero debt. Substantial cash reserves of $63.9M providing runway for continued R&D operations. ChatGPT: Strong liquidity with a 6.01x current ratio and meaningful cash relative to liabilities. No meaningful balance-sheet leverage, reducing refinancing and solvency pressure.

What are the risks of investing in ALMS?

Claude: Massive operating losses of -$98.4M against only $1.7M revenue indicates unsustainable burn rate unsupported by revenue. Negative operating cash flow of -$87.1M will deplete reserves within 12-18 months if business model does not change. ChatGPT: Operating model is highly unprofitable, with operating margin of -1615.5% and net margin of -679.9%. Cash burn is severe, with operating cash flow of -$297.62M and free cash flow of -$298.27M.

What is ALMS's revenue and growth?

Alumis Inc.. reported revenue of $1.7M.

Does ALMS pay dividends?

Alumis Inc.. does not currently pay dividends.

Where can I find ALMS SEC filings?

Official SEC filings for Alumis Inc.. (CIK: 0001847367) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is ALMS's EPS?

Alumis Inc.. has a diluted EPS of $-0.74.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined grade reflects both perspectives for balanced insights.

What is ALMS's fundamental grade?

Based on our AI fundamental analysis in June 2026, Alumis Inc.. has a C grade with 66% confidence. Review the strengths and risks sections above for full context. This is not investment advice.

Is ALMS stock overvalued or undervalued?

Valuation metrics for ALMS: ROE of -16.4% (sector avg: 15%), net margin of -5,344.8% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

What is ALMS's AI grade for 2026?

Our dual AI analysis gives Alumis Inc.. a combined C grade for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is ALMS's free cash flow?

Alumis Inc..'s operating cash flow is $-87.1M, with capital expenditures of $164.0K. FCF margin is -5,011.3%.

How does ALMS compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -5,344.8% (avg: 12%), ROE -16.4% (avg: 15%), current ratio 7.51 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: May 15, 2026 | Data as of: 2026-03-31 | Powered by Claude AI