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Alumis Inc.. (ALMS) Stock Fundamental Analysis & AI Rating 2026

ALMS Nasdaq Pharmaceutical Preparations DE CIK: 0001847367
Updated This Month • Analysis: Mar 19, 2026 • SEC Data: 2025-09-30
Combined AI Rating
SELL
92% Confidence
AGREEMENT
STRONG SELL
95% Conf
SELL
88% Conf

📊 ALMS Key Takeaways

Revenue: $22.1M
Net Margin: -679.9%
Free Cash Flow: $-298.3M
Current Ratio: 6.01x
Debt/Equity: 0.00x
EPS: $-1.92
AI Rating: STRONG SELL with 95% confidence
Alumis Inc.. (ALMS) receives a SELL rating with 92% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $22.1M, net profit margin of -679.9%, and return on equity (ROE) of -39.1%, Alumis Inc.. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete ALMS stock analysis for 2026.

Is Alumis Inc.. (ALMS) a Good Investment?

Claude

Alumis is a pre-revenue pharmaceutical company with severe cash burn and unsustainable operating losses. Despite holding adequate cash reserves ($65.3M), the company is burning approximately $298M annually in free cash flow, indicating a runway of less than 3 quarters at current burn rates. Without demonstrated revenue generation or clear path to profitability, the fundamental financial position is critically deteriorating.

ChatGPT

Alumis shows extremely weak current fundamentals, with minimal revenue relative to its cost base, deeply negative operating and net margins, and nearly $300M of annual free cash outflow. The balance sheet is a mitigating factor because liquidity is strong and leverage is negligible, but the business still depends on translating pipeline spending into durable revenue before cash burn materially erodes that cushion.

Why Buy Alumis Inc.. Stock? ALMS Key Strengths

Claude
  • + Strong liquidity position with $65.3M cash and 6.01x current ratio providing near-term operational flexibility
  • + Low leverage with minimal debt obligations reducing immediate refinancing risk
  • + Substantial asset base of $488M suggests intellectual property or development assets in pharmaceutical pipeline
ChatGPT
  • + Strong liquidity with a 6.01x current ratio and meaningful cash relative to liabilities
  • + No meaningful balance-sheet leverage, reducing refinancing and solvency pressure
  • + Positive reported revenue indicates at least some non-zero commercial or collaboration inflow

ALMS Stock Risks: Alumis Inc.. Investment Risks

Claude
  • ! Catastrophic cash burn of -$298.3M in free cash flow annually will deplete reserves within 2-3 quarters at current rates
  • ! Minimal revenue of $22.1M against -$357.4M operating loss indicates no viable commercial operations or product market fit
  • ! Negative net margin of -679.9% and -$150.4M net loss demonstrate inability to control costs relative to revenue
  • ! Early-stage pharma company with unproven drug development success - typical attrition rates are extremely high
  • ! Operating losses and negative cash flow unsustainable without major capital raise, partnership, or acquisition
ChatGPT
  • ! Operating model is highly unprofitable, with operating margin of -1615.5% and net margin of -679.9%
  • ! Cash burn is severe, with operating cash flow of -$297.62M and free cash flow of -$298.27M
  • ! Growth quality is weak because revenue remains far too small to support the current expense base

Key Metrics to Watch

Claude
  • * Quarterly cash burn rate and remaining cash runway - critical for survival timeline
  • * Revenue growth trajectory - any meaningful revenue would require successful clinical trials and FDA approvals
  • * Operating expense reduction initiatives and burn rate improvement
  • * Financing activities and capital raise announcements - likely necessity given cash depletion timeline
  • * Pipeline clinical trial progress and regulatory milestones for lead candidates
ChatGPT
  • * Quarterly operating cash burn versus cash and equivalents
  • * Revenue scale-up and operating expense discipline

Alumis Inc.. (ALMS) Financial Metrics & Key Ratios

Revenue
$22.1M
Net Income
$-150.4M
EPS (Diluted)
$-1.92
Free Cash Flow
$-298.3M
Total Assets
$488.0M
Cash Position
$65.3M

💡 AI Analyst Insight

Strong liquidity with a 6.01x current ratio provides a solid financial cushion.

ALMS Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin -1,615.5%
Net Margin -679.9%
ROE -39.1%
ROA -30.8%
FCF Margin -1,348.4%

ALMS vs Healthcare Sector: How Alumis Inc.. Compares

How Alumis Inc.. compares to Healthcare sector averages

Net Margin
ALMS -679.9%
vs
Sector Avg 12.0%
ALMS Sector
ROE
ALMS -39.1%
vs
Sector Avg 15.0%
ALMS Sector
Current Ratio
ALMS 6.0x
vs
Sector Avg 2.0x
ALMS Sector
Debt/Equity
ALMS 0.0x
vs
Sector Avg 0.6x
ALMS Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Alumis Inc.. Stock Overvalued? ALMS Valuation Analysis 2026

Based on fundamental analysis, Alumis Inc.. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-39.1%
Sector avg: 15%
Net Profit Margin
-679.9%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Alumis Inc.. Balance Sheet: ALMS Debt, Cash & Liquidity

Current Ratio
6.01x
Quick Ratio
6.01x
Debt/Equity
0.00x
Debt/Assets
21.2%
Interest Coverage
N/A
Long-term Debt
N/A

ALMS Revenue & Earnings Growth: 5-Year Financial Trend

ALMS 5-year financial data: Year 2025: Revenue $24.1M, Net Income -$294.2M, EPS $-10.38.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Alumis Inc..'s revenue has remained relatively flat over the 5-year period, with a 0% decline. The most recent EPS of $-10.38 indicates the company is currently unprofitable.

ALMS Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-1,348.4%
Free cash flow / Revenue

ALMS Quarterly Earnings & Performance

Quarterly financial performance data for Alumis Inc.. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 $2.1M -$49.8M $-1.06
Q2 2025 $2.7M -$39.6M $-0.61
Q1 2025 $17.4M -$49.8M $-1.82

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Alumis Inc.. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$297.6M
Cash generated from operations
Stock Buybacks
$17.0K
Shares repurchased (TTM)
Capital Expenditures
$653.0K
Investment in assets
Dividends
None
No dividend program

ALMS SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Alumis Inc.. (CIK: 0001847367)

📋 Recent SEC Filings

Date Form Document Action
Apr 3, 2026 4 xslF345X06/tm2611109-3_4seq1.xml View →
Apr 3, 2026 4 xslF345X06/tm2611109-2_4seq1.xml View →
Apr 3, 2026 4 xslF345X06/tm2611109-1_4seq1.xml View →
Mar 30, 2026 8-K tm269978d1_8k.htm View →
Mar 19, 2026 10-K alms-20251231x10k.htm View →

Frequently Asked Questions about ALMS

What is the AI rating for ALMS?

Alumis Inc.. (ALMS) has a Combined AI Rating of SELL from Claude (STRONG SELL) and ChatGPT (SELL) with 92% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are ALMS's key strengths?

Claude: Strong liquidity position with $65.3M cash and 6.01x current ratio providing near-term operational flexibility. Low leverage with minimal debt obligations reducing immediate refinancing risk. ChatGPT: Strong liquidity with a 6.01x current ratio and meaningful cash relative to liabilities. No meaningful balance-sheet leverage, reducing refinancing and solvency pressure.

What are the risks of investing in ALMS?

Claude: Catastrophic cash burn of -$298.3M in free cash flow annually will deplete reserves within 2-3 quarters at current rates. Minimal revenue of $22.1M against -$357.4M operating loss indicates no viable commercial operations or product market fit. ChatGPT: Operating model is highly unprofitable, with operating margin of -1615.5% and net margin of -679.9%. Cash burn is severe, with operating cash flow of -$297.62M and free cash flow of -$298.27M.

What is ALMS's revenue and growth?

Alumis Inc.. reported revenue of $22.1M.

Does ALMS pay dividends?

Alumis Inc.. does not currently pay dividends.

Where can I find ALMS SEC filings?

Official SEC filings for Alumis Inc.. (CIK: 0001847367) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is ALMS's EPS?

Alumis Inc.. has a diluted EPS of $-1.92.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is ALMS a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Alumis Inc.. has a SELL rating with 92% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is ALMS stock overvalued or undervalued?

Valuation metrics for ALMS: ROE of -39.1% (sector avg: 15%), net margin of -679.9% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy ALMS stock in 2026?

Our dual AI analysis gives Alumis Inc.. a combined SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is ALMS's free cash flow?

Alumis Inc..'s operating cash flow is $-297.6M, with capital expenditures of $653.0K. FCF margin is -1,348.4%.

How does ALMS compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -679.9% (avg: 12%), ROE -39.1% (avg: 15%), current ratio 6.01 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Mar 19, 2026 | Data as of: 2025-09-30 | Powered by Claude AI