← Back to All US Stocks

Actuate Therapeutics, Inc.. (ACTU) Stock Fundamental Analysis & AI Rating 2026

ACTU Nasdaq Pharmaceutical Preparations DE CIK: 0001652935
Updated This Month • Analysis: Mar 19, 2026 • SEC Data: 2025-09-30
Combined AI Rating
SELL
85% Confidence
AGREEMENT
STRONG SELL
92% Conf
SELL
78% Conf

📊 ACTU Key Takeaways

Revenue: N/A
Net Margin: N/A
Free Cash Flow: $-15.5M
Current Ratio: 2.74x
Debt/Equity: 0.00x
EPS: $-0.88
AI Rating: STRONG SELL with 92% confidence
Actuate Therapeutics, Inc.. (ACTU) receives a SELL rating with 85% confidence from our AI fundamental analysis based on SEC 10-K filings., and return on equity (ROE) of -161.6% Below is our complete ACTU stock analysis for 2026.

Is Actuate Therapeutics, Inc.. (ACTU) a Good Investment?

Claude

Actuate Therapeutics is a pre-revenue biotech company with severe operational losses (-$17.8M operating income) and negative free cash flow (-$15.5M), indicating no commercialized products generating revenue. Despite adequate liquidity (2.74x current ratio, $16.9M cash), the company is burning cash rapidly with only ~1 year of runway at current burn rates, creating acute financing risk absent near-term catalysts.

ChatGPT

Actuate Therapeutics appears to be a pre-revenue biotech with no commercial income, persistent operating losses, and deeply negative returns on equity and assets, which makes current fundamental quality weak. The balance sheet is relatively clean with high cash balances, solid near-term liquidity, and no long-term debt, but cash burn of roughly $15.5M against $16.9M of cash suggests limited runway without meaningful clinical or financing progress.

Why Buy Actuate Therapeutics, Inc.. Stock? ACTU Key Strengths

Claude
  • + Strong liquidity position with $16.9M in cash and 2.74x current ratio providing near-term operational runway
  • + Zero debt obligations eliminating refinancing risk and balance sheet leverage concerns
  • + Lean asset base ($17.7M total assets) with modest liability burden ($6.8M), indicating no legacy encumbrances
ChatGPT
  • + Strong liquidity with a 2.74x current and quick ratio
  • + Cash represents most of the asset base, supporting near-term operations
  • + No meaningful long-term debt, limiting balance-sheet leverage risk

ACTU Stock Risks: Actuate Therapeutics, Inc.. Investment Risks

Claude
  • ! Pre-revenue stage with zero product commercialization and no revenue generation capability
  • ! Severe cash burn of $15.5M annually with only ~1 year of financial runway remaining before depletion
  • ! Negative profitability metrics across all dimensions (ROE -161.6%, ROA -99.8%, operating margin N/A) with no path to profitability visible
  • ! Dilutive financing requirement imminent given runway constraints, likely destroying shareholder value
ChatGPT
  • ! No revenue base, so the business is not yet self-sustaining
  • ! Large recurring losses and negative operating cash flow indicate heavy cash burn
  • ! Likely need for future capital raises if burn remains near current levels

Key Metrics to Watch

Claude
  • * Cash burn rate and remaining cash runway duration (critical survival metric)
  • * Clinical trial progress and regulatory milestones for any lead candidates
  • * Operating expense trends and evidence of cost efficiency improvements
ChatGPT
  • * Quarterly operating cash burn relative to cash on hand
  • * Clinical and regulatory progress that could translate into revenue or partnership inflows

Actuate Therapeutics, Inc.. (ACTU) Financial Metrics & Key Ratios

Revenue
N/A
Net Income
$-17.7M
EPS (Diluted)
$-0.88
Free Cash Flow
$-15.5M
Total Assets
$17.7M
Cash Position
$16.9M

💡 AI Analyst Insight

Strong liquidity with a 2.74x current ratio provides a solid financial cushion.

ACTU Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin N/A
Net Margin N/A
ROE -161.6%
ROA -99.8%
FCF Margin N/A

ACTU vs Healthcare Sector: How Actuate Therapeutics, Inc.. Compares

How Actuate Therapeutics, Inc.. compares to Healthcare sector averages

Net Margin
ACTU 0.0%
vs
Sector Avg 12.0%
ACTU Sector
ROE
ACTU -161.6%
vs
Sector Avg 15.0%
ACTU Sector
Current Ratio
ACTU 2.7x
vs
Sector Avg 2.0x
ACTU Sector
Debt/Equity
ACTU 0.0x
vs
Sector Avg 0.6x
ACTU Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Actuate Therapeutics, Inc.. Stock Overvalued? ACTU Valuation Analysis 2026

Based on fundamental analysis, Actuate Therapeutics, Inc.. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-161.6%
Sector avg: 15%
Net Profit Margin
N/A
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Actuate Therapeutics, Inc.. Balance Sheet: ACTU Debt, Cash & Liquidity

Current Ratio
2.74x
Quick Ratio
2.74x
Debt/Equity
0.00x
Debt/Assets
38.3%
Interest Coverage
N/A
Long-term Debt
N/A

ACTU Revenue & Earnings Growth: 5-Year Financial Trend

ACTU 5-year financial data:
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Actuate Therapeutics, Inc..'s revenue has remained relatively flat over the 5-year period, with a 0% decline. The most recent EPS of $-3.26 indicates the company is currently unprofitable.

ACTU Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
N/A
Free cash flow / Revenue

Actuate Therapeutics, Inc.. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$15.5M
Cash generated from operations
Dividends
None
No dividend program

ACTU SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Actuate Therapeutics, Inc.. (CIK: 0001652935)

📋 Recent SEC Filings

Date Form Document Action
Apr 6, 2026 DEF 14A actuate_def14a1.htm View →
Apr 1, 2026 4 xslF345X06/ownership.xml View →
Apr 1, 2026 4 xslF345X06/ownership.xml View →
Apr 1, 2026 4 xslF345X06/ownership.xml View →
Mar 26, 2026 10-K actuate_i10k-123125.htm View →

Frequently Asked Questions about ACTU

What is the AI rating for ACTU?

Actuate Therapeutics, Inc.. (ACTU) has a Combined AI Rating of SELL from Claude (STRONG SELL) and ChatGPT (SELL) with 85% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are ACTU's key strengths?

Claude: Strong liquidity position with $16.9M in cash and 2.74x current ratio providing near-term operational runway. Zero debt obligations eliminating refinancing risk and balance sheet leverage concerns. ChatGPT: Strong liquidity with a 2.74x current and quick ratio. Cash represents most of the asset base, supporting near-term operations.

What are the risks of investing in ACTU?

Claude: Pre-revenue stage with zero product commercialization and no revenue generation capability. Severe cash burn of $15.5M annually with only ~1 year of financial runway remaining before depletion. ChatGPT: No revenue base, so the business is not yet self-sustaining. Large recurring losses and negative operating cash flow indicate heavy cash burn.

What is ACTU's revenue and growth?

Actuate Therapeutics, Inc.. reported revenue of N/A.

Does ACTU pay dividends?

Actuate Therapeutics, Inc.. does not currently pay dividends.

Where can I find ACTU SEC filings?

Official SEC filings for Actuate Therapeutics, Inc.. (CIK: 0001652935) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is ACTU's EPS?

Actuate Therapeutics, Inc.. has a diluted EPS of $-0.88.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is ACTU a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Actuate Therapeutics, Inc.. has a SELL rating with 85% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is ACTU stock overvalued or undervalued?

Valuation metrics for ACTU: ROE of -161.6% (sector avg: 15%), net margin of N/A (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy ACTU stock in 2026?

Our dual AI analysis gives Actuate Therapeutics, Inc.. a combined SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is ACTU's free cash flow?

Actuate Therapeutics, Inc..'s operating cash flow is $-15.5M, with capital expenditures of N/A.

How does ACTU compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin N/A (avg: 12%), ROE -161.6% (avg: 15%), current ratio 2.74 (avg: 2).

Top Rated Stocks
NSSC 92% MLI 92% MELI 92% MDXG 92% MANH 92% INVA 92% GGG 92% GCT 92% FTNT 92% FSLR 92%
Sector: All Healthcare Stocks →
Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Mar 19, 2026 | Data as of: 2025-09-30 | Powered by Claude AI