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Replimune Group, Inc. (REPL) Stock Fundamental Analysis & AI Rating 2026

REPL Nasdaq Biological Products, (No Diagnostic Substances) DE CIK: 0001737953
Updated This Month • Analysis: Apr 8, 2026 • SEC Data: 2025-12-31
Combined AI Rating
STRONG SELL
74% Confidence
STRONG AGREEMENT
STRONG SELL
75% Conf
STRONG SELL
72% Conf

📊 REPL Key Takeaways

Revenue: $0.0
Net Margin: N/A
Free Cash Flow: $-228.4M
Current Ratio: 5.60x
Debt/Equity: 0.23x
EPS: $-2.62
AI Rating: STRONG SELL with 75% confidence
Replimune Group, Inc. (REPL) receives a STRONG SELL rating with 74% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $0, and return on equity (ROE) of -114.3%, Replimune Group, Inc. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete REPL stock analysis for 2026.

Is Replimune Group, Inc. (REPL) a Good Investment?

Claude

Replimune is a pre-revenue biotech company with no commercialized products, posting $246.6M in operating losses and burning $228.4M in free cash flow annually. Despite a solid cash position of $123M and conservative leverage (0.23x D/E), the burn rate implies only 6-7 months of runway at current spending levels, necessitating immediate capital raises or dramatic operational changes to avoid liquidity crisis.

ChatGPT

Replimune remains pre‑revenue with very large operating losses and deeply negative returns on assets and equity, indicating no current path to profitability. While liquidity and leverage are acceptable today, the magnitude of cash burn relative to cash on hand implies a short runway and a high likelihood of near‑term dilutive financing absent revenue initiation or significant cost reduction.

Why Buy Replimune Group, Inc. Stock? REPL Key Strengths

Claude
  • + Strong cash position of $123.0M provides near-term operational runway
  • + Conservative leverage with 0.23x debt-to-equity ratio and low absolute debt of $47.6M
  • + Excellent liquidity ratios (5.60x current/quick ratio) indicate ability to meet short-term obligations
  • + Significant insider activity (16 Form 4 filings in 90 days) suggests management confidence in pipeline
ChatGPT
  • + Strong liquidity with 5.6x current ratio and $123M cash
  • + Moderate leverage (0.23x D/E) with manageable long‑term debt
  • + Low capital intensity (capex ~$4M) provides operating flexibility

REPL Stock Risks: Replimune Group, Inc. Investment Risks

Claude
  • ! Pre-revenue company with zero sales indicates no validated commercial products
  • ! Massive annual cash burn of $228.4M (free cash flow) against only $123M cash on hand
  • ! Operating losses of $246.6M with negative ROE (-114.3%) and ROA (-72.2%) demonstrate unprofitable operations
  • ! Only 6-7 months of cash runway at current burn rate; requires external financing or operational pivot
  • ! High clinical/regulatory execution risk typical of early-stage biotech with no approved products
ChatGPT
  • ! Sustained zero revenue and heavy operating losses (-$247M) and FCF (-$228M)
  • ! Short cash runway relative to burn, elevating dilution/financing risk
  • ! Negative ROE/ROA and interest coverage (-55.7x) signal weak profitability profile

Key Metrics to Watch

Claude
  • * Cash burn rate and remaining runway (critical for survival)
  • * Clinical trial progress and FDA regulatory milestones for pipeline programs
  • * Cash position and capital raise announcements or dilution
  • * Operating expense trends and whether burn rate can be reduced
ChatGPT
  • * Operating cash flow (quarterly burn)
  • * Operating expenses trend (R&D + SG&A)

Replimune Group, Inc. (REPL) Financial Metrics & Key Ratios

Revenue
$0.0
Net Income
$-240.7M
EPS (Diluted)
$-2.62
Free Cash Flow
$-228.4M
Total Assets
$333.6M
Cash Position
$123.0M

💡 AI Analyst Insight

Strong liquidity with a 5.60x current ratio provides a solid financial cushion.

REPL Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin N/A
Net Margin N/A
ROE -114.3%
ROA -72.2%
FCF Margin N/A

REPL vs Healthcare Sector: How Replimune Group, Inc. Compares

How Replimune Group, Inc. compares to Healthcare sector averages

Net Margin
REPL 0.0%
vs
Sector Avg 12.0%
REPL Sector
ROE
REPL -114.3%
vs
Sector Avg 15.0%
REPL Sector
Current Ratio
REPL 5.6x
vs
Sector Avg 2.0x
REPL Sector
Debt/Equity
REPL 0.2x
vs
Sector Avg 0.6x
REPL Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Replimune Group, Inc. Stock Overvalued? REPL Valuation Analysis 2026

Based on fundamental analysis, Replimune Group, Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-114.3%
Sector avg: 15%
Net Profit Margin
N/A
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.23x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Replimune Group, Inc. Balance Sheet: REPL Debt, Cash & Liquidity

Current Ratio
5.60x
Quick Ratio
5.60x
Debt/Equity
0.23x
Debt/Assets
36.9%
Interest Coverage
-55.67x
Long-term Debt
$47.6M

REPL Revenue & Earnings Growth: 5-Year Financial Trend

REPL 5-year financial data:
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Replimune Group, Inc.'s revenue has remained relatively flat over the 5-year period, with a 0% decline. The most recent EPS of $-3.24 indicates the company is currently unprofitable.

REPL Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
N/A
Free cash flow / Revenue

REPL Quarterly Earnings & Performance

Quarterly financial performance data for Replimune Group, Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2018 N/A -$4.2M N/A
Q2 2018 N/A -$4.0M N/A
Q1 2018 N/A -$2.6M N/A

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Replimune Group, Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$224.2M
Cash generated from operations
Capital Expenditures
$4.2M
Investment in assets
Dividends
None
No dividend program

REPL SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Replimune Group, Inc. (CIK: 0001737953)

📋 Recent SEC Filings

Date Form Document Action
Apr 13, 2026 8-K tm2611633d1_8k.htm View →
Apr 7, 2026 4 xslF345X06/ownership.xml View →
Apr 7, 2026 4 xslF345X06/tm2611350-7_4seq1.xml View →
Apr 7, 2026 4 xslF345X06/tm2611350-14_4seq1.xml View →
Apr 7, 2026 4 xslF345X06/tm2611350-6_4seq1.xml View →

Frequently Asked Questions about REPL

What is the AI rating for REPL?

Replimune Group, Inc. (REPL) has a Combined AI Rating of STRONG SELL from Claude (STRONG SELL) and ChatGPT (STRONG SELL) with 74% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are REPL's key strengths?

Claude: Strong cash position of $123.0M provides near-term operational runway. Conservative leverage with 0.23x debt-to-equity ratio and low absolute debt of $47.6M. ChatGPT: Strong liquidity with 5.6x current ratio and $123M cash. Moderate leverage (0.23x D/E) with manageable long‑term debt.

What are the risks of investing in REPL?

Claude: Pre-revenue company with zero sales indicates no validated commercial products. Massive annual cash burn of $228.4M (free cash flow) against only $123M cash on hand. ChatGPT: Sustained zero revenue and heavy operating losses (-$247M) and FCF (-$228M). Short cash runway relative to burn, elevating dilution/financing risk.

What is REPL's revenue and growth?

Replimune Group, Inc. reported revenue of $0.0.

Does REPL pay dividends?

Replimune Group, Inc. does not currently pay dividends.

Where can I find REPL SEC filings?

Official SEC filings for Replimune Group, Inc. (CIK: 0001737953) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is REPL's EPS?

Replimune Group, Inc. has a diluted EPS of $-2.62.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is REPL a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Replimune Group, Inc. has a STRONG SELL rating with 74% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is REPL stock overvalued or undervalued?

Valuation metrics for REPL: ROE of -114.3% (sector avg: 15%), net margin of N/A (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy REPL stock in 2026?

Our dual AI analysis gives Replimune Group, Inc. a combined STRONG SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is REPL's free cash flow?

Replimune Group, Inc.'s operating cash flow is $-224.2M, with capital expenditures of $4.2M.

How does REPL compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin N/A (avg: 12%), ROE -114.3% (avg: 15%), current ratio 5.60 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Apr 8, 2026 | Data as of: 2025-12-31 | Powered by Claude AI