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Neurocrine Biosciences Inc. (NBIX) Stock Fundamental Analysis & AI Rating 2026

NBIX Nasdaq Biological Products, (No Diagnostic Substances) DE CIK: 0000914475
Recently Updated • Analysis: Apr 13, 2026 • SEC Data: 2025-12-31
Combined AI Rating
BUY
84% Confidence
AGREEMENT
STRONG BUY
88% Conf
BUY
80% Conf

📊 NBIX Key Takeaways

Revenue: $2.9B
Net Margin: 16.7%
Free Cash Flow: $748.7M
Current Ratio: 3.39x
Debt/Equity: 0.00x
EPS: $4.67
AI Rating: STRONG BUY with 88% confidence
Neurocrine Biosciences Inc. (NBIX) receives a BUY rating with 84% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $2.9B, net profit margin of 16.7%, and return on equity (ROE) of 14.7%, Neurocrine Biosciences Inc. demonstrates strong fundamentals in the Healthcare sector. Below is our complete NBIX stock analysis for 2026.

Is Neurocrine Biosciences Inc. (NBIX) a Good Investment?

Claude

Neurocrine demonstrates exceptional financial health with 21.4% revenue growth, fortress-like balance sheet (zero debt, $713M cash), and outstanding free cash flow generation ($748.7M, 26.2% margin). The company's combination of strong top-line growth, 21.6% operating margins, and robust cash conversion provides excellent financial flexibility for biotech R&D investment and shareholder returns.

ChatGPT

Strong 21%+ revenue growth, double‑digit operating and net margins, and a debt‑free, highly liquid balance sheet underscore sound fundamentals. Despite flat net income YoY, cash generation is robust (26% FCF margin), supporting continued R&D and commercialization without balance‑sheet strain.

Why Buy Neurocrine Biosciences Inc. Stock? NBIX Key Strengths

Claude
  • + Exceptional free cash flow generation of $748.7M with 26.2% FCF margin, demonstrating high-quality revenue
  • + Zero long-term debt with $713M cash position and 3.39x current ratio provides fortress balance sheet for biotech operations
  • + Strong 21.4% YoY revenue growth with 21.6% operating margin and 16.7% net margin showing profitable scaling
  • + EPS growth of 41.9% YoY despite flat net income indicates disciplined capital allocation through share buybacks
ChatGPT
  • + Rapid topline growth with solid operating margin (21.6%)
  • + Debt-free, excellent liquidity (3.39x current) and massive interest coverage
  • + Strong cash generation ($783M OCF; 26% FCF margin)

NBIX Stock Risks: Neurocrine Biosciences Inc. Investment Risks

Claude
  • ! Net income flat YoY (+0.0%) despite 21.4% revenue growth suggests rising operating costs or one-time charges requiring investigation
  • ! Biotech sector exposure to regulatory risk, drug development failures, patent expirations, and clinical trial outcomes
  • ! Operating margin sustainability uncertain if R&D expenses increase or product revenue declines
ChatGPT
  • ! Flat net income YoY suggests rising costs or one‑offs
  • ! Biopharma regulatory/reimbursement and product concentration risk
  • ! Gross margin not reported, reducing cost-structure visibility

Key Metrics to Watch

Claude
  • * Net income growth trajectory relative to revenue growth for signs of margin compression
  • * Operating cash flow sustainability and capital allocation decisions (R&D spending, M&A activity)
  • * Product pipeline advancement and regulatory approval status for revenue growth drivers
ChatGPT
  • * Operating margin trend and R&D/SG&A as % of revenue
  • * Free cash flow margin and OCF growth vs. revenue

Neurocrine Biosciences Inc. (NBIX) Financial Metrics & Key Ratios

Revenue
$2.9B
Net Income
$478.6M
EPS (Diluted)
$4.67
Free Cash Flow
$748.7M
Total Assets
$4.6B
Cash Position
$713.0M

💡 AI Analyst Insight

The 26.2% free cash flow margin provides substantial flexibility for dividends, buybacks, and strategic investments. Strong liquidity with a 3.39x current ratio provides a solid financial cushion.

NBIX Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin 21.6%
Net Margin 16.7%
ROE 14.7%
ROA 10.3%
FCF Margin 26.2%

NBIX vs Healthcare Sector: How Neurocrine Biosciences Inc. Compares

How Neurocrine Biosciences Inc. compares to Healthcare sector averages

Net Margin
NBIX 16.7%
vs
Sector Avg 12.0%
NBIX Sector
ROE
NBIX 14.7%
vs
Sector Avg 15.0%
NBIX Sector
Current Ratio
NBIX 3.4x
vs
Sector Avg 2.0x
NBIX Sector
Debt/Equity
NBIX 0.0x
vs
Sector Avg 0.6x
NBIX Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Neurocrine Biosciences Inc. Stock Overvalued? NBIX Valuation Analysis 2026

Based on fundamental analysis, Neurocrine Biosciences Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
14.7%
Sector avg: 15%
Net Profit Margin
16.7%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Neurocrine Biosciences Inc. Balance Sheet: NBIX Debt, Cash & Liquidity

Current Ratio
3.39x
Quick Ratio
3.30x
Debt/Equity
0.00x
Debt/Assets
29.8%
Interest Coverage
562.82x
Long-term Debt
N/A

NBIX Revenue & Earnings Growth: 5-Year Financial Trend

NBIX 5-year financial data: Year 2021: Revenue $1.1B, Net Income $37.0M, EPS $0.39. Year 2022: Revenue $1.5B, Net Income $407.3M, EPS $4.16. Year 2023: Revenue $1.9B, Net Income $89.6M, EPS $0.92. Year 2024: Revenue $2.4B, Net Income $154.5M, EPS $1.56. Year 2025: Revenue $2.9B, Net Income $249.7M, EPS $2.47.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Neurocrine Biosciences Inc.'s revenue has grown significantly by 152% over the 5-year period, indicating strong business expansion. The most recent EPS of $2.47 reflects profitable operations.

NBIX Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
26.2%
Free cash flow / Revenue

NBIX Quarterly Earnings & Performance

Quarterly financial performance data for Neurocrine Biosciences Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 $622.1M $129.8M $1.24
Q2 2025 $590.2M $65.0M $0.63
Q1 2025 $515.3M $7.9M $0.08
Q3 2024 $498.8M $83.1M $0.82
Q2 2024 $452.7M $18.9M $0.19
Q1 2024 $420.4M $43.4M $0.42
Q3 2023 $387.9M $65.5M $0.67
Q2 2023 $378.2M -$3.0M $-0.03

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Neurocrine Biosciences Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
$782.7M
Cash generated from operations
Stock Buybacks
$167.7M
Shares repurchased (TTM)
Capital Expenditures
$34.0M
Investment in assets
Dividends
None
No dividend program

NBIX SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Neurocrine Biosciences Inc. (CIK: 0000914475)

📋 Recent SEC Filings

Date Form Document Action
Apr 15, 2026 DEF 14A nbix-20260415.htm View →
Apr 6, 2026 8-K d110123d8k.htm View →
Mar 5, 2026 4 xslF345X05/wk-form4_1772752714.xml View →
Feb 23, 2026 4 xslF345X05/wk-form4_1771891938.xml View →
Feb 17, 2026 4 xslF345X05/wk-form4_1771368557.xml View →

Frequently Asked Questions about NBIX

What is the AI rating for NBIX?

Neurocrine Biosciences Inc. (NBIX) has a Combined AI Rating of BUY from Claude (STRONG BUY) and ChatGPT (BUY) with 84% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are NBIX's key strengths?

Claude: Exceptional free cash flow generation of $748.7M with 26.2% FCF margin, demonstrating high-quality revenue. Zero long-term debt with $713M cash position and 3.39x current ratio provides fortress balance sheet for biotech operations. ChatGPT: Rapid topline growth with solid operating margin (21.6%). Debt-free, excellent liquidity (3.39x current) and massive interest coverage.

What are the risks of investing in NBIX?

Claude: Net income flat YoY (+0.0%) despite 21.4% revenue growth suggests rising operating costs or one-time charges requiring investigation. Biotech sector exposure to regulatory risk, drug development failures, patent expirations, and clinical trial outcomes. ChatGPT: Flat net income YoY suggests rising costs or one‑offs. Biopharma regulatory/reimbursement and product concentration risk.

What is NBIX's revenue and growth?

Neurocrine Biosciences Inc. reported revenue of $2.9B.

Does NBIX pay dividends?

Neurocrine Biosciences Inc. does not currently pay dividends.

Where can I find NBIX SEC filings?

Official SEC filings for Neurocrine Biosciences Inc. (CIK: 0000914475) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is NBIX's EPS?

Neurocrine Biosciences Inc. has a diluted EPS of $4.67.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is NBIX a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Neurocrine Biosciences Inc. has a BUY rating with 84% confidence. The AI analysis suggests favorable fundamentals based on SEC filings. This is not investment advice.

Is NBIX stock overvalued or undervalued?

Valuation metrics for NBIX: ROE of 14.7% (sector avg: 15%), net margin of 16.7% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy NBIX stock in 2026?

Our dual AI analysis gives Neurocrine Biosciences Inc. a combined BUY rating for 2026. Revenue is data pending, with profitability above sector average. Always conduct your own research.

What is NBIX's free cash flow?

Neurocrine Biosciences Inc.'s operating cash flow is $782.7M, with capital expenditures of $34.0M. FCF margin is 26.2%.

How does NBIX compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin 16.7% (avg: 12%), ROE 14.7% (avg: 15%), current ratio 3.39 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Apr 13, 2026 | Data as of: 2025-12-31 | Powered by Claude AI