← Back to All US Stocks

Illumina, Inc.. (ILMN) Stock Fundamental Analysis & AI Rating 2026

ILMN Nasdaq Laboratory Analytical Instruments DE CIK: 0001110803
Updated This Month • Analysis: Mar 19, 2026 • SEC Data: 2025-12-28
Combined AI Rating
BUY
84% Confidence
NEUTRAL
STRONG BUY
88% Conf
HOLD
79% Conf

📊 ILMN Key Takeaways

Revenue: $4.3B
Net Margin: 19.6%
Free Cash Flow: $931.0M
Current Ratio: 2.08x
Debt/Equity: 0.25x
EPS: $5.45
AI Rating: STRONG BUY with 88% confidence
Illumina, Inc.. (ILMN) receives a BUY rating with 84% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $4.3B, net profit margin of 19.6%, and return on equity (ROE) of 31.2%, Illumina, Inc.. demonstrates strong fundamentals in the Industrial sector. Below is our complete ILMN stock analysis for 2026.

Is Illumina, Inc.. (ILMN) a Good Investment?

Claude

Illumina demonstrates exceptional financial health with robust profitability metrics (66.1% gross margin, 19.6% net margin) and outstanding ROE of 31.2%, despite flat revenue growth. The company generates substantial free cash flow of $931M (21.4% margin) with minimal leverage (0.25x D/E) and strong liquidity, providing financial flexibility for investments and shareholder returns. Net income surged 169.5% YoY, indicating operational efficiency improvements and potential margin expansion even in a growth-constrained environment.

ChatGPT

Illumina shows strong core fundamentals with high gross margins, solid operating profitability, strong free cash flow generation, and a conservative balance sheet. However, revenue is slightly declining, which weakens growth quality, and the sharp jump in net income appears stronger than underlying sales growth, suggesting investors should watch whether earnings strength is sustainable.

Why Buy Illumina, Inc.. Stock? ILMN Key Strengths

Claude
  • + Exceptional profitability with 66.1% gross margin and 19.6% net margin
  • + Outstanding return metrics with 31.2% ROE and 12.8% ROA
  • + Strong free cash flow generation of $931M with 21.4% FCF margin
  • + Fortress balance sheet with 2.08x current ratio and 0.25x debt-to-equity
  • + Net income jumped 169.5% YoY indicating significant operational leverage
  • + Exceptional interest coverage of 44.8x demonstrates minimal solvency risk
ChatGPT
  • + High profitability with 66.1% gross margin, 18.6% operating margin, and 19.6% net margin
  • + Strong financial health with 2.08x current ratio, low 0.25x debt-to-equity, and 44.8x interest coverage
  • + Robust cash generation with $1.08B operating cash flow and $931M free cash flow

ILMN Stock Risks: Illumina, Inc.. Investment Risks

Claude
  • ! Revenue declined 0.7% YoY indicating top-line stagnation and potential market headwinds
  • ! Operating margin of 18.6% may be vulnerable if revenue declines persist
  • ! Heavy concentration in life sciences instrumentation sector creates cyclical exposure
  • ! Capital intensity with $148M annual capex required to maintain competitive position
  • ! Sharp 169.5% net income increase appears unsustainable and may reflect one-time items or cost restructuring
ChatGPT
  • ! Revenue declined 0.7% year over year, indicating limited near-term top-line momentum
  • ! Net income growth far exceeded revenue growth, raising questions about earnings quality and sustainability
  • ! Business may face operating leverage pressure if revenue softness persists

Key Metrics to Watch

Claude
  • * Revenue growth trajectory and customer demand trends
  • * Gross margin sustainability as scale potentially becomes challenged
  • * Free cash flow conversion and capex requirements for R&D
  • * Operating leverage and ability to maintain net income growth with flat revenues
  • * Debt levels and covenant compliance on $673M long-term debt
ChatGPT
  • * Revenue growth trend and instrument/consumables demand
  • * Operating margin and free cash flow consistency

Illumina, Inc.. (ILMN) Financial Metrics & Key Ratios

Revenue
$4.3B
Net Income
$850.0M
EPS (Diluted)
$5.45
Free Cash Flow
$931.0M
Total Assets
$6.6B
Cash Position
$1.4B

💡 AI Analyst Insight

The 21.4% free cash flow margin provides substantial flexibility for dividends, buybacks, and strategic investments. Strong liquidity with a 2.08x current ratio provides a solid financial cushion.

ILMN Profit Margin, ROE & Profitability Analysis

Gross Margin 66.1%
Operating Margin 18.6%
Net Margin 19.6%
ROE 31.2%
ROA 12.8%
FCF Margin 21.4%

ILMN vs Industrial Sector: How Illumina, Inc.. Compares

How Illumina, Inc.. compares to Industrial sector averages

Net Margin
ILMN 19.6%
vs
Sector Avg 10.0%
ILMN Sector
ROE
ILMN 31.2%
vs
Sector Avg 15.0%
ILMN Sector
Current Ratio
ILMN 2.1x
vs
Sector Avg 1.8x
ILMN Sector
Debt/Equity
ILMN 0.2x
vs
Sector Avg 0.7x
ILMN Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Illumina, Inc.. Stock Overvalued? ILMN Valuation Analysis 2026

Based on fundamental analysis, Illumina, Inc.. appears fundamentally strong relative to the Industrial sector in 2026.

Return on Equity
31.2%
Sector avg: 15%
Net Profit Margin
19.6%
Sector avg: 10%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.25x
Sector avg: 0.7x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Illumina, Inc.. Balance Sheet: ILMN Debt, Cash & Liquidity

Current Ratio
2.08x
Quick Ratio
1.72x
Debt/Equity
0.25x
Debt/Assets
0.0%
Interest Coverage
44.83x
Long-term Debt
$673.0M

ILMN Revenue & Earnings Growth: 5-Year Financial Trend

ILMN 5-year financial data: Year 2021: Revenue $4.5B, Net Income $1.0B, EPS $6.74. Year 2022: Revenue $4.6B, Net Income N/A, EPS $4.45. Year 2023: Revenue $4.6B, Net Income $762.0M, EPS $5.04. Year 2024: Revenue $4.6B, Net Income -$4.4B, EPS $-28.00. Year 2025: Revenue $4.5B, Net Income -$1.2B, EPS $-7.34.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Illumina, Inc..'s revenue has remained relatively flat over the 5-year period, with a 0% decline. The most recent EPS of $-7.34 indicates the company is currently unprofitable.

ILMN Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
21.4%
Free cash flow / Revenue

ILMN Quarterly Earnings & Performance

Quarterly financial performance data for Illumina, Inc.. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 $1.1B -$126.0M $0.98
Q2 2025 $1.1B -$126.0M $1.49
Q1 2025 $1.0B -$126.0M $-0.79
Q3 2024 $1.1B $3.0M $4.42
Q2 2024 $1.1B $3.0M $-1.46
Q1 2024 $1.1B $3.0M $0.02
Q3 2023 $1.1B $3.0M $-4.77
Q2 2023 $1.2B $3.0M $-1.46

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Illumina, Inc.. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
$1.1B
Cash generated from operations
Stock Buybacks
$742.0M
Shares repurchased (TTM)
Capital Expenditures
$148.0M
Investment in assets
Dividends
None
No dividend program

ILMN SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Illumina, Inc.. (CIK: 0001110803)

📋 Recent SEC Filings

Date Form Document Action
Apr 9, 2026 DEF 14A d13789ddef14a.htm View →
Apr 2, 2026 4 xslF345X06/form4.xml View →
Apr 2, 2026 4 xslF345X06/form4.xml View →
Apr 2, 2026 8-K ilmn-20260402.htm View →
Mar 9, 2026 4 xslF345X05/form4.xml View →

Frequently Asked Questions about ILMN

What is the AI rating for ILMN?

Illumina, Inc.. (ILMN) has a Combined AI Rating of BUY from Claude (STRONG BUY) and ChatGPT (HOLD) with 84% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are ILMN's key strengths?

Claude: Exceptional profitability with 66.1% gross margin and 19.6% net margin. Outstanding return metrics with 31.2% ROE and 12.8% ROA. ChatGPT: High profitability with 66.1% gross margin, 18.6% operating margin, and 19.6% net margin. Strong financial health with 2.08x current ratio, low 0.25x debt-to-equity, and 44.8x interest coverage.

What are the risks of investing in ILMN?

Claude: Revenue declined 0.7% YoY indicating top-line stagnation and potential market headwinds. Operating margin of 18.6% may be vulnerable if revenue declines persist. ChatGPT: Revenue declined 0.7% year over year, indicating limited near-term top-line momentum. Net income growth far exceeded revenue growth, raising questions about earnings quality and sustainability.

What is ILMN's revenue and growth?

Illumina, Inc.. reported revenue of $4.3B.

Does ILMN pay dividends?

Illumina, Inc.. does not currently pay dividends.

Where can I find ILMN SEC filings?

Official SEC filings for Illumina, Inc.. (CIK: 0001110803) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is ILMN's EPS?

Illumina, Inc.. has a diluted EPS of $5.45.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is ILMN a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Illumina, Inc.. has a BUY rating with 84% confidence. The AI analysis suggests favorable fundamentals based on SEC filings. This is not investment advice.

Is ILMN stock overvalued or undervalued?

Valuation metrics for ILMN: ROE of 31.2% (sector avg: 15%), net margin of 19.6% (sector avg: 10%). Higher ROE suggests strong returns relative to peers.

Should I buy ILMN stock in 2026?

Our dual AI analysis gives Illumina, Inc.. a combined BUY rating for 2026. Revenue is data pending, with profitability above sector average. Always conduct your own research.

What is ILMN's free cash flow?

Illumina, Inc..'s operating cash flow is $1.1B, with capital expenditures of $148.0M. FCF margin is 21.4%.

How does ILMN compare to other Industrial stocks?

Vs Industrial sector averages: Net margin 19.6% (avg: 10%), ROE 31.2% (avg: 15%), current ratio 2.08 (avg: 1.8).

Why is ILMN's return on equity (ROE) so high?

Illumina, Inc.. has a return on equity of 31.2%, significantly above the Industrial sector average of 15%. A high ROE indicates the company is efficient at generating profits from shareholder equity. This is supported by a 19.6% net margin.

Top Rated Stocks
NSSC 92% MLI 92% MELI 92% MDXG 92% MANH 92% INVA 92% GGG 92% GCT 92% FTNT 92% FSLR 92%
Sector: All Industrial Stocks →
Browse: Buy Stocks High Confidence Stocks High ROE Stocks
Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Mar 19, 2026 | Data as of: 2025-12-28 | Powered by Claude AI