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Halozyme Therapeutics, Inc.. (HALO) Stock Fundamental Analysis & AI Rating 2026

HALO Nasdaq Biological Products, (No Diagnostic Substances) DE CIK: 0001159036
Recently Updated • Analysis: Apr 11, 2026 • SEC Data: 2025-12-31
Combined AI Rating
BUY
64% Confidence
AGREEMENT
HOLD
58% Conf
BUY
70% Conf

📊 HALO Key Takeaways

Revenue: $1.4B
Net Margin: 22.7%
Free Cash Flow: $644.6M
Current Ratio: 4.66x
Debt/Equity: 43.89x
EPS: $2.56
AI Rating: HOLD with 58% confidence
Halozyme Therapeutics, Inc.. (HALO) receives a BUY rating with 64% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $1.4B, net profit margin of 22.7%, and return on equity (ROE) of 649.2%, Halozyme Therapeutics, Inc.. demonstrates strong fundamentals in the Healthcare sector. Below is our complete HALO stock analysis for 2026.

Is Halozyme Therapeutics, Inc.. (HALO) a Good Investment?

Claude

HaloZyme demonstrates strong revenue growth of 37.6% YoY and exceptional free cash flow generation ($644.6M), but declining net income (-28.6% YoY) and EPS (-25.4% YoY) despite revenue expansion signal deteriorating profitability quality. Extremely high leverage (43.89x debt-to-equity) with minimal equity base ($48.8M) presents significant financial risk that offsets strong operational cash generation.

ChatGPT

Revenue growth is strong and operating profitability with exceptional free cash flow conversion supports balance sheet flexibility despite heavy leverage. Liquidity and interest coverage are robust, though the YoY earnings decline and anomalously low gross margin signal mix/accounting volatility to monitor.

Why Buy Halozyme Therapeutics, Inc.. Stock? HALO Key Strengths

Claude
  • + Robust revenue growth at 37.6% YoY indicating strong market demand
  • + Exceptional free cash flow of $644.6M with 46.2% FCF margin showing quality earnings
  • + Excellent short-term liquidity with current ratio of 4.66x and quick ratio of 3.66x
  • + Strong operating income margin of 33.6% and net margin of 22.7%
  • + Outstanding interest coverage ratio of 104.1x indicating manageable debt service
ChatGPT
  • + Strong top-line growth (+37.6% YoY) with high operating margin (33.6%)
  • + Exceptional free cash flow (46% margin) with minimal capex needs
  • + Solid liquidity (4.66x current) and very high interest coverage (104x)

HALO Stock Risks: Halozyme Therapeutics, Inc.. Investment Risks

Claude
  • ! Profitability deterioration: net income down 28.6% YoY and EPS down 25.4% despite 37.6% revenue growth
  • ! Extreme financial leverage with 43.89x debt-to-equity ratio and $2.1B long-term debt against only $48.8M equity
  • ! Abnormally low gross margin of 0.4% creates structural profitability concerns and data quality questions
  • ! Thin equity cushion ($48.8M on $2.5B total assets) limits financial flexibility and increases distress risk
ChatGPT
  • ! High leverage and thin equity (Debt/Equity 43.9x) raise refinancing/covenant risk
  • ! Net income and EPS down YoY despite growth, indicating margin/expense volatility
  • ! Extremely low reported gross margin (0.4%) suggests mix or accounting anomalies that could compress profitability if persistent

Key Metrics to Watch

Claude
  • * Net income and EPS trajectory - must stabilize and return to growth
  • * Gross margin normalization - 0.4% is unsustainable and requires investigation
  • * Debt reduction pace and leverage ratio trend - current 43.89x is dangerously high
  • * Operating cash flow sustainability - confirm $651.6M is repeatable
  • * Revenue growth sustainability - verify 37.6% growth rate continues
ChatGPT
  • * Free cash flow (FCF) margin
  • * Interest coverage

Halozyme Therapeutics, Inc.. (HALO) Financial Metrics & Key Ratios

Revenue
$1.4B
Net Income
$316.9M
EPS (Diluted)
$2.56
Free Cash Flow
$644.6M
Total Assets
$2.5B
Cash Position
$133.8M

💡 AI Analyst Insight

The 46.2% free cash flow margin provides substantial flexibility for dividends, buybacks, and strategic investments. Strong liquidity with a 4.66x current ratio provides a solid financial cushion.

HALO Profit Margin, ROE & Profitability Analysis

Gross Margin 0.4%
Operating Margin 33.6%
Net Margin 22.7%
ROE 649.2%
ROA 12.5%
FCF Margin 46.2%

HALO vs Healthcare Sector: How Halozyme Therapeutics, Inc.. Compares

How Halozyme Therapeutics, Inc.. compares to Healthcare sector averages

Net Margin
HALO 22.7%
vs
Sector Avg 12.0%
HALO Sector
ROE
HALO 649.2%
vs
Sector Avg 15.0%
HALO Sector
Current Ratio
HALO 4.7x
vs
Sector Avg 2.0x
HALO Sector
Debt/Equity
HALO 43.9x
vs
Sector Avg 0.6x
HALO Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Halozyme Therapeutics, Inc.. Stock Overvalued? HALO Valuation Analysis 2026

Based on fundamental analysis, Halozyme Therapeutics, Inc.. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
649.2%
Sector avg: 15%
Net Profit Margin
22.7%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
43.89x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Halozyme Therapeutics, Inc.. Balance Sheet: HALO Debt, Cash & Liquidity

Current Ratio
4.66x
Quick Ratio
3.66x
Debt/Equity
43.89x
Debt/Assets
98.1%
Interest Coverage
104.06x
Long-term Debt
$2.1B

HALO Revenue & Earnings Growth: 5-Year Financial Trend

HALO 5-year financial data: Year 2021: Revenue $443.3M, Net Income -$72.2M, EPS $-0.50. Year 2022: Revenue $660.1M, Net Income $129.1M, EPS $0.91. Year 2023: Revenue $829.3M, Net Income $402.7M, EPS $2.74. Year 2024: Revenue $1.0B, Net Income $202.1M, EPS $1.44. Year 2025: Revenue $1.4B, Net Income $281.6M, EPS $2.10.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Halozyme Therapeutics, Inc..'s revenue has grown significantly by 215% over the 5-year period, indicating strong business expansion. The most recent EPS of $2.10 reflects profitable operations.

HALO Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
46.2%
Free cash flow / Revenue

HALO Quarterly Earnings & Performance

Quarterly financial performance data for Halozyme Therapeutics, Inc.. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 $290.1M $137.0M $1.05
Q2 2025 $231.4M $93.2M $0.72
Q1 2025 $195.9M $76.8M $0.60
Q3 2024 $216.0M $81.8M $0.61
Q2 2024 $221.0M $74.8M $0.56
Q1 2024 $162.1M $39.6M $0.29
Q3 2023 $209.0M $61.6M $0.44
Q2 2023 $152.4M $22.7M $0.16

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Halozyme Therapeutics, Inc.. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
$651.6M
Cash generated from operations
Stock Buybacks
$342.4M
Shares repurchased (TTM)
Capital Expenditures
$7.0M
Investment in assets
Dividends
None
No dividend program

HALO SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Halozyme Therapeutics, Inc.. (CIK: 0001159036)

📋 Recent SEC Filings

Date Form Document Action
Apr 7, 2026 4 xslF345X06/wk-form4_1775596415.xml View →
Apr 2, 2026 4 xslF345X06/wk-form4_1775168956.xml View →
Apr 2, 2026 4 xslF345X06/wk-form4_1775168915.xml View →
Mar 23, 2026 DEF 14A halo-20260323.htm View →
Mar 12, 2026 8-K halo-20260312.htm View →

Frequently Asked Questions about HALO

What is the AI rating for HALO?

Halozyme Therapeutics, Inc.. (HALO) has a Combined AI Rating of BUY from Claude (HOLD) and ChatGPT (BUY) with 64% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are HALO's key strengths?

Claude: Robust revenue growth at 37.6% YoY indicating strong market demand. Exceptional free cash flow of $644.6M with 46.2% FCF margin showing quality earnings. ChatGPT: Strong top-line growth (+37.6% YoY) with high operating margin (33.6%). Exceptional free cash flow (46% margin) with minimal capex needs.

What are the risks of investing in HALO?

Claude: Profitability deterioration: net income down 28.6% YoY and EPS down 25.4% despite 37.6% revenue growth. Extreme financial leverage with 43.89x debt-to-equity ratio and $2.1B long-term debt against only $48.8M equity. ChatGPT: High leverage and thin equity (Debt/Equity 43.9x) raise refinancing/covenant risk. Net income and EPS down YoY despite growth, indicating margin/expense volatility.

What is HALO's revenue and growth?

Halozyme Therapeutics, Inc.. reported revenue of $1.4B.

Does HALO pay dividends?

Halozyme Therapeutics, Inc.. does not currently pay dividends.

Where can I find HALO SEC filings?

Official SEC filings for Halozyme Therapeutics, Inc.. (CIK: 0001159036) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is HALO's EPS?

Halozyme Therapeutics, Inc.. has a diluted EPS of $2.56.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is HALO a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Halozyme Therapeutics, Inc.. has a BUY rating with 64% confidence. The AI analysis suggests favorable fundamentals based on SEC filings. This is not investment advice.

Is HALO stock overvalued or undervalued?

Valuation metrics for HALO: ROE of 649.2% (sector avg: 15%), net margin of 22.7% (sector avg: 12%). Higher ROE suggests strong returns relative to peers.

Should I buy HALO stock in 2026?

Our dual AI analysis gives Halozyme Therapeutics, Inc.. a combined BUY rating for 2026. Revenue is data pending, with profitability above sector average. Always conduct your own research.

What is HALO's free cash flow?

Halozyme Therapeutics, Inc..'s operating cash flow is $651.6M, with capital expenditures of $7.0M. FCF margin is 46.2%.

How does HALO compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin 22.7% (avg: 12%), ROE 649.2% (avg: 15%), current ratio 4.66 (avg: 2).

Is Halozyme Therapeutics, Inc.. carrying too much debt?

HALO has a debt-to-equity ratio of 43.89x, which is above the Healthcare sector average of 0.6x. However, the current ratio of 4.66 suggests adequate short-term liquidity.

Why is HALO's return on equity (ROE) so high?

Halozyme Therapeutics, Inc.. has a return on equity of 649.2%, significantly above the Healthcare sector average of 15%. A high ROE indicates the company is efficient at generating profits from shareholder equity. This is supported by a 22.7% net margin.

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Apr 11, 2026 | Data as of: 2025-12-31 | Powered by Claude AI