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Cellectis S.A. (CLLS) Stock Fundamental Analysis & AI Rating 2026

CLLS Nasdaq Biological Products, (No Diagnostic Substances) I0 CIK: 0001627281
Updated This Month • Analysis: Mar 22, 2026 • SEC Data: 2026-03-22
Combined AI Rating
SELL
44% Confidence
AGREEMENT
SELL
15% Conf
HOLD
73% Conf

📊 CLLS Key Takeaways

Revenue: N/A
Net Margin: N/A
Free Cash Flow: N/A
Current Ratio: N/A
Debt/Equity: N/A
EPS: $0.00
AI Rating: SELL with 15% confidence
Cellectis S.A. (CLLS) receives a SELL rating with 44% confidence from our AI fundamental analysis based on SEC 10-K filings. Below is our complete CLLS stock analysis for 2026.

Is Cellectis S.A. (CLLS) a Good Investment?

Claude

Cellectis S.A. is a pre-revenue or early-stage biotech company with critically limited financial data available through SEC EDGAR, making fundamental analysis impossible. The near-complete absence of disclosed financial metrics—including revenue, profitability, assets, and cash position—prevents any meaningful assessment of financial health, operational performance, or sustainability.

ChatGPT

Cellectis has a stronger balance sheet than many clinical-stage biotech peers, with $383.5 million of assets, $131.0 million of equity, and roughly $260.3 million of cash plus current financial assets at December 31, 2024; by June 30, 2025, it still reported $226.1 million of cash and deposits and said this should fund operations into the second half of 2027. Fundamentals are improving but still mixed: 2024 net loss narrowed to $36.8 million and first-half 2025 operating loss improved year over year, yet the company remains dependent on collaboration revenue, has no therapeutic product sales, and returned to operating cash burn in 2025.

Why Buy Cellectis S.A. Stock? CLLS Key Strengths

Claude
  • + Operates in high-potential biological products sector with gene editing technology focus
  • + Nasdaq listing indicates access to capital markets for funding
  • + No identifiable near-term debt obligations mentioned in available data
ChatGPT
  • + Large liquidity cushion and disclosed runway into the second half of 2027 reduce near-term financing pressure
  • + 2024 and first-half 2025 showed better operating performance, with higher collaboration revenue and a narrower operating loss in first-half 2025 versus first-half 2024
  • + Financial obligations appear manageable relative to cash and deposits, supporting continued R&D investment in the pipeline

CLLS Stock Risks: Cellectis S.A. Investment Risks

Claude
  • ! Complete lack of revenue or profitability data suggests pre-commercial stage with burn rate concerns
  • ! Inability to assess cash runway or liquidity position poses existential business continuity risk
  • ! Absence of disclosed financial metrics prevents evaluation of R&D spending efficiency and clinical trial progress
  • ! No insider buying activity detected in last 90 days, potentially signaling low management confidence
  • ! Biotech sector inherently high-risk with uncertain regulatory and clinical development outcomes
ChatGPT
  • ! Business is still fundamentally unprofitable and has not generated any therapeutic product sales to date
  • ! Revenue quality is weak because it relies heavily on partnerships, milestones, and accounting-driven collaboration recognition rather than recurring commercial demand
  • ! Clinical, regulatory, and funding risk remain high if trials disappoint or cash burn stays elevated and forces new capital raising

Key Metrics to Watch

Claude
  • * Cash position and quarterly burn rate
  • * Clinical trial progress and regulatory milestones
  • * Revenue recognition from any approved products or partnerships
  • * Operating expenses and R&D spending efficiency
ChatGPT
  • * Quarterly operating cash burn versus collaboration cash inflows
  • * Collaboration revenue conversion and operating loss trend relative to R&D spend

Cellectis S.A. (CLLS) Financial Metrics & Key Ratios

Revenue
N/A
Net Income
N/A
EPS (Diluted)
$0.00
Free Cash Flow
N/A
Total Assets
N/A
Cash Position
N/A

💡 AI Analyst Insight

The current ratio below 1.0x warrants monitoring of short-term liquidity.

CLLS Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin N/A
Net Margin N/A
ROE N/A
ROA N/A
FCF Margin N/A

CLLS vs Healthcare Sector: How Cellectis S.A. Compares

How Cellectis S.A. compares to Healthcare sector averages

Net Margin
CLLS 0.0%
vs
Sector Avg 12.0%
CLLS Sector
ROE
CLLS 0.0%
vs
Sector Avg 15.0%
CLLS Sector
Current Ratio
CLLS 0.0x
vs
Sector Avg 2.0x
CLLS Sector
Debt/Equity
CLLS 0.0x
vs
Sector Avg 0.6x
CLLS Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Cellectis S.A. Stock Overvalued? CLLS Valuation Analysis 2026

Based on fundamental analysis, Cellectis S.A. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
N/A
Sector avg: 15%
Net Profit Margin
N/A
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
N/A
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Cellectis S.A. Balance Sheet: CLLS Debt, Cash & Liquidity

Current Ratio
N/A
Quick Ratio
N/A
Debt/Equity
N/A
Debt/Assets
0.0%
Interest Coverage
N/A
Long-term Debt
N/A

CLLS Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
N/A
Free cash flow / Revenue

CLLS SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Cellectis S.A. (CIK: 0001627281)

📋 Recent SEC Filings

Date Form Document Action
Nov 9, 2023 SC 13D tm2330279d1_sc13d.htm View →
May 3, 2022 SC 13G cellectis_13g.htm View →
Jan 12, 2022 SC 13G Cellectis31122021.txt View →
Nov 10, 2020 SC 13G tm2035564d1_sc13g.htm View →
Oct 20, 2020 4 xslF345X03/doc4.xml View →

Frequently Asked Questions about CLLS

What is the AI rating for CLLS?

Cellectis S.A. (CLLS) has a Combined AI Rating of SELL from Claude (SELL) and ChatGPT (HOLD) with 44% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are CLLS's key strengths?

Claude: Operates in high-potential biological products sector with gene editing technology focus. Nasdaq listing indicates access to capital markets for funding. ChatGPT: Large liquidity cushion and disclosed runway into the second half of 2027 reduce near-term financing pressure. 2024 and first-half 2025 showed better operating performance, with higher collaboration revenue and a narrower operating loss in first-half 2025 versus first-half 2024.

What are the risks of investing in CLLS?

Claude: Complete lack of revenue or profitability data suggests pre-commercial stage with burn rate concerns. Inability to assess cash runway or liquidity position poses existential business continuity risk. ChatGPT: Business is still fundamentally unprofitable and has not generated any therapeutic product sales to date. Revenue quality is weak because it relies heavily on partnerships, milestones, and accounting-driven collaboration recognition rather than recurring commercial demand.

What is CLLS's revenue and growth?

Cellectis S.A. reported revenue of N/A.

Does CLLS pay dividends?

Cellectis S.A. does not currently pay dividends.

Where can I find CLLS SEC filings?

Official SEC filings for Cellectis S.A. (CIK: 0001627281) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is CLLS's EPS?

Cellectis S.A. has a diluted EPS of $0.00.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is CLLS a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Cellectis S.A. has a SELL rating with 44% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is CLLS stock overvalued or undervalued?

Valuation metrics for CLLS: ROE of N/A (sector avg: 15%), net margin of N/A (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy CLLS stock in 2026?

Our dual AI analysis gives Cellectis S.A. a combined SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is CLLS's free cash flow?

Cellectis S.A.'s operating cash flow is N/A, with capital expenditures of N/A.

How does CLLS compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin N/A (avg: 12%), ROE N/A (avg: 15%), current ratio N/A (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Mar 22, 2026 | Data as of: 2026-03-22 | Powered by Claude AI