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Codexis, Inc.. (CDXS) Stock Fundamental Analysis & AI Rating 2026

CDXS Nasdaq Industrial Organic Chemicals DE CIK: 0001200375
Updated This Month • Analysis: Mar 22, 2026 • SEC Data: 2025-12-31
Combined AI Rating
SELL
83% Confidence
STRONG AGREEMENT
SELL
85% Conf
SELL
81% Conf

📊 CDXS Key Takeaways

Revenue: $70.4M
Net Margin: -62.5%
Free Cash Flow: $-23.8M
Current Ratio: 3.82x
Debt/Equity: 0.79x
EPS: $-0.50
AI Rating: SELL with 85% confidence
Codexis, Inc.. (CDXS) receives a SELL rating with 83% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $70.4M, net profit margin of -62.5%, and return on equity (ROE) of -87.0%, Codexis, Inc.. demonstrates mixed fundamentals in the Materials sector. Below is our complete CDXS stock analysis for 2026.

Is Codexis, Inc.. (CDXS) a Good Investment?

Claude

Codexis is a pre-profitability biotech/industrial chemicals company burning cash despite modest revenue growth, with operating losses of -$41.7M and negative free cash flow of -$23.8M. While the company maintains adequate liquidity (3.82x current ratio and $50.8M cash), it is consuming capital at an unsustainable rate and will deplete reserves within 2-3 years at current burn rates without achieving profitability or securing additional funding.

ChatGPT

Codexis is delivering solid top-line growth, but that growth is not translating into a sustainable earnings profile, with deeply negative operating margins, net losses, and negative free cash flow. The balance sheet still provides near-term flexibility through strong liquidity, but the combination of weak profitability, high cash burn, and negative returns on equity and assets makes the fundamental outlook unattractive until operating leverage materially improves.

Why Buy Codexis, Inc.. Stock? CDXS Key Strengths

Claude
  • + Revenue growth of 18.6% YoY demonstrates ongoing demand for services/products
  • + Strong liquidity position with $50.8M cash and 3.82x current ratio providing near-term financial flexibility
  • + Reasonable debt-to-equity ratio of 0.79x indicates manageable leverage relative to equity base
ChatGPT
  • + Revenue grew 18.6% year over year, showing continued commercial demand
  • + Current ratio of 3.82x and cash of $50.79M support near-term liquidity
  • + Debt/equity of 0.79x is manageable relative to available liquidity

CDXS Stock Risks: Codexis, Inc.. Investment Risks

Claude
  • ! Massive operating losses (-$59.3% operating margin) with no clear path to profitability in near term
  • ! Severe negative free cash flow of -$23.8M annually will exhaust cash reserves in approximately 2 years without operational improvement or external funding
  • ! High insider trading activity (7 Form 4 filings in 90 days) coupled with deteriorating financials may indicate insider uncertainty about near-term prospects
ChatGPT
  • ! Operating margin of -59.3% and net margin of -62.5% indicate an unsustainable cost structure
  • ! Free cash flow of -$23.85M and negative operating cash flow increase funding risk if losses persist
  • ! ROE of -87.0% and ROA of -29.8% reflect weak capital efficiency and poor underlying economics

Key Metrics to Watch

Claude
  • * Operating cash flow trajectory - must improve to positive before cash depletion
  • * Gross profit margin data - critical missing metric that may reveal unit economics issues
  • * Path to operating break-even - timeline and milestones for achieving EBITDA profitability
ChatGPT
  • * Operating cash flow and free cash flow trend
  • * Operating margin improvement versus revenue growth

Codexis, Inc.. (CDXS) Financial Metrics & Key Ratios

Revenue
$70.4M
Net Income
$-44.0M
EPS (Diluted)
$-0.50
Free Cash Flow
$-23.8M
Total Assets
$147.8M
Cash Position
$50.8M

💡 AI Analyst Insight

Strong liquidity with a 3.82x current ratio provides a solid financial cushion.

CDXS Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin -59.3%
Net Margin -62.5%
ROE -87.0%
ROA -29.8%
FCF Margin -33.9%

CDXS vs Materials Sector: How Codexis, Inc.. Compares

How Codexis, Inc.. compares to Materials sector averages

Net Margin
CDXS -62.5%
vs
Sector Avg 10.0%
CDXS Sector
ROE
CDXS -87.0%
vs
Sector Avg 14.0%
CDXS Sector
Current Ratio
CDXS 3.8x
vs
Sector Avg 1.6x
CDXS Sector
Debt/Equity
CDXS 0.8x
vs
Sector Avg 0.6x
CDXS Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Codexis, Inc.. Stock Overvalued? CDXS Valuation Analysis 2026

Based on fundamental analysis, Codexis, Inc.. shows some fundamental concerns relative to the Materials sector in 2026.

Return on Equity
-87.0%
Sector avg: 14%
Net Profit Margin
-62.5%
Sector avg: 10%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.79x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Codexis, Inc.. Balance Sheet: CDXS Debt, Cash & Liquidity

Current Ratio
3.82x
Quick Ratio
3.75x
Debt/Equity
0.79x
Debt/Assets
65.8%
Interest Coverage
-3,210.69x
Long-term Debt
$40.1M

CDXS Revenue & Earnings Growth: 5-Year Financial Trend

CDXS 5-year financial data: Year 2021: Revenue $104.8M, Net Income -$11.9M, EPS $-0.21. Year 2022: Revenue $138.6M, Net Income -$24.0M, EPS $-0.40. Year 2023: Revenue $138.6M, Net Income -$21.3M, EPS $-0.33. Year 2024: Revenue $138.6M, Net Income -$33.6M, EPS $-0.51. Year 2025: Revenue $70.4M, Net Income -$76.2M, EPS $-1.12.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Codexis, Inc..'s revenue has declined by 33% over the 5-year period, indicating business contraction. The most recent EPS of $-1.12 indicates the company is currently unprofitable.

CDXS Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-33.9%
Free cash flow / Revenue

CDXS Quarterly Earnings & Performance

Quarterly financial performance data for Codexis, Inc.. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 $8.6M -$19.6M $-0.22
Q2 2025 $8.0M -$13.3M $-0.16
Q1 2025 $7.5M -$11.5M $-0.16
Q3 2024 $9.3M -$20.6M $-0.29
Q2 2024 $8.0M -$11.5M $-0.17
Q1 2024 $13.0M -$11.5M $-0.16
Q3 2023 $9.3M -$10.0M $-0.15
Q2 2023 $21.3M -$2.6M $-0.04

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Codexis, Inc.. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$19.4M
Cash generated from operations
Capital Expenditures
$4.5M
Investment in assets
Dividends
None
No dividend program

CDXS SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Codexis, Inc.. (CIK: 0001200375)

📋 Recent SEC Filings

Date Form Document Action
Apr 14, 2026 8-K d96482d8k.htm View →
Mar 11, 2026 10-K cdxs-20251231.htm View →
Mar 11, 2026 8-K d106216d8k.htm View →
Feb 25, 2026 4 xslF345X05/form4.xml View →
Feb 25, 2026 4 xslF345X05/form4.xml View →

Frequently Asked Questions about CDXS

What is the AI rating for CDXS?

Codexis, Inc.. (CDXS) has a Combined AI Rating of SELL from Claude (SELL) and ChatGPT (SELL) with 83% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are CDXS's key strengths?

Claude: Revenue growth of 18.6% YoY demonstrates ongoing demand for services/products. Strong liquidity position with $50.8M cash and 3.82x current ratio providing near-term financial flexibility. ChatGPT: Revenue grew 18.6% year over year, showing continued commercial demand. Current ratio of 3.82x and cash of $50.79M support near-term liquidity.

What are the risks of investing in CDXS?

Claude: Massive operating losses (-$59.3% operating margin) with no clear path to profitability in near term. Severe negative free cash flow of -$23.8M annually will exhaust cash reserves in approximately 2 years without operational improvement or external funding. ChatGPT: Operating margin of -59.3% and net margin of -62.5% indicate an unsustainable cost structure. Free cash flow of -$23.85M and negative operating cash flow increase funding risk if losses persist.

What is CDXS's revenue and growth?

Codexis, Inc.. reported revenue of $70.4M.

Does CDXS pay dividends?

Codexis, Inc.. does not currently pay dividends.

Where can I find CDXS SEC filings?

Official SEC filings for Codexis, Inc.. (CIK: 0001200375) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is CDXS's EPS?

Codexis, Inc.. has a diluted EPS of $-0.50.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is CDXS a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Codexis, Inc.. has a SELL rating with 83% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is CDXS stock overvalued or undervalued?

Valuation metrics for CDXS: ROE of -87.0% (sector avg: 14%), net margin of -62.5% (sector avg: 10%). Compare these metrics with sector averages to assess valuation.

Should I buy CDXS stock in 2026?

Our dual AI analysis gives Codexis, Inc.. a combined SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is CDXS's free cash flow?

Codexis, Inc..'s operating cash flow is $-19.4M, with capital expenditures of $4.5M. FCF margin is -33.9%.

How does CDXS compare to other Materials stocks?

Vs Materials sector averages: Net margin -62.5% (avg: 10%), ROE -87.0% (avg: 14%), current ratio 3.82 (avg: 1.6).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Mar 22, 2026 | Data as of: 2025-12-31 | Powered by Claude AI