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Biocryst Pharmaceuticals Inc. (BCRX) Stock Fundamental Analysis & AI Rating 2026

BCRX Nasdaq Biological Products, (No Diagnostic Substances) DE CIK: 0000882796
Updated This Month • Analysis: Mar 20, 2026 • SEC Data: 2025-12-31
Combined AI Rating
BUY
72% Confidence
AGREEMENT
HOLD
62% Conf
BUY
82% Conf

📊 BCRX Key Takeaways

Revenue: $874.8M
Net Margin: 30.2%
Free Cash Flow: $344.9M
Current Ratio: 2.06x
Debt/Equity: N/A
EPS: $1.21
AI Rating: HOLD with 62% confidence
Biocryst Pharmaceuticals Inc. (BCRX) receives a BUY rating with 72% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $874.8M, net profit margin of 30.2%, Biocryst Pharmaceuticals Inc. demonstrates strong fundamentals in the Healthcare sector. Below is our complete BCRX stock analysis for 2026.

Is Biocryst Pharmaceuticals Inc. (BCRX) a Good Investment?

Claude

BioCryst demonstrates exceptional revenue growth (+94.1% YoY) and strong profitability metrics (39% operating margin, 30.2% net margin) with robust free cash flow generation ($344.9M). However, the negative stockholders' equity of -$119.2M represents a critical balance sheet deterioration that must be resolved, creating meaningful financial risk despite operational strength.

ChatGPT

BioCryst Pharmaceuticals shows a sharp fundamental inflection, with revenue up 94.1% YoY and net income up 396.9% YoY, while converting that growth into strong operating margins and substantial free cash flow. The business now appears materially more self-funding, but negative equity and a liability-heavy balance sheet still warrant some caution despite strong liquidity.

Why Buy Biocryst Pharmaceuticals Inc. Stock? BCRX Key Strengths

Claude
  • + Exceptional revenue growth of 94.1% year-over-year indicating strong market demand
  • + Impressive net income growth of 396.9% with net margin of 30.2% showing operational leverage
  • + Strong free cash flow generation at $344.9M (39.4% FCF margin) providing financial flexibility
  • + Healthy liquidity position with current ratio of 2.06x and quick ratio of 2.03x
  • + Robust operating cash flow of $347.4M with minimal capital expenditure requirements
ChatGPT
  • + Revenue growth is exceptionally strong at 94.1% YoY, indicating major commercial momentum
  • + Profitability has improved meaningfully, with 39.0% operating margin and 30.2% net margin
  • + Cash generation is high quality, with $347.37M operating cash flow and $344.90M free cash flow

BCRX Stock Risks: Biocryst Pharmaceuticals Inc. Investment Risks

Claude
  • ! Critical balance sheet weakness with negative stockholders' equity of -$119.2M indicating liabilities exceed assets by $119.2M
  • ! Total liabilities of $633.3M exceed total assets of $514.2M, creating solvency concerns
  • ! Significant insider trading activity with 10 Form 4 filings in last 90 days warrants monitoring for insider confidence signals
  • ! Negative equity makes traditional leverage metrics meaningless and limits financing flexibility
  • ! Sustainability of 94% revenue growth rates uncertain; margin compression risk if growth moderates
ChatGPT
  • ! Stockholders equity is negative, which signals accumulated balance sheet strain despite current profitability
  • ! Total liabilities exceed total assets, limiting financial flexibility if operating performance weakens
  • ! Recent results may be difficult to sustain if growth normalizes after a breakout year

Key Metrics to Watch

Claude
  • * Stockholders' equity trajectory and debt reduction plan to return to positive equity position
  • * Revenue growth sustainability and gross margin trends as company scales
  • * Free cash flow generation capability and deployment strategy to strengthen balance sheet
  • * Operating leverage and net margin sustainability at current profitability levels
  • * Insider transaction patterns and management commentary on balance sheet restoration
ChatGPT
  • * Revenue growth durability and net margin retention
  • * Cash balance relative to liabilities and ongoing free cash flow generation

Biocryst Pharmaceuticals Inc. (BCRX) Financial Metrics & Key Ratios

Revenue
$874.8M
Net Income
$263.9M
EPS (Diluted)
$1.21
Free Cash Flow
$344.9M
Total Assets
$514.2M
Cash Position
$89.7M

💡 AI Analyst Insight

The 39.4% free cash flow margin provides substantial flexibility for dividends, buybacks, and strategic investments. Strong liquidity with a 2.06x current ratio provides a solid financial cushion.

BCRX Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin 39.0%
Net Margin 30.2%
ROE N/A
ROA 51.3%
FCF Margin 39.4%

BCRX vs Healthcare Sector: How Biocryst Pharmaceuticals Inc. Compares

How Biocryst Pharmaceuticals Inc. compares to Healthcare sector averages

Net Margin
BCRX 30.2%
vs
Sector Avg 12.0%
BCRX Sector
ROE
BCRX 0.0%
vs
Sector Avg 15.0%
BCRX Sector
Current Ratio
BCRX 2.1x
vs
Sector Avg 2.0x
BCRX Sector
Debt/Equity
BCRX 0.0x
vs
Sector Avg 0.6x
BCRX Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Biocryst Pharmaceuticals Inc. Stock Overvalued? BCRX Valuation Analysis 2026

Based on fundamental analysis, Biocryst Pharmaceuticals Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
N/A
Sector avg: 15%
Net Profit Margin
30.2%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
N/A
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Biocryst Pharmaceuticals Inc. Balance Sheet: BCRX Debt, Cash & Liquidity

Current Ratio
2.06x
Quick Ratio
2.03x
Debt/Equity
N/A
Debt/Assets
123.2%
Interest Coverage
6.93x
Long-term Debt
$0.0

BCRX Revenue & Earnings Growth: 5-Year Financial Trend

BCRX 5-year financial data: Year 2021: Revenue $157.2M, Net Income -$108.9M, EPS N/A. Year 2022: Revenue $270.8M, Net Income -$182.8M, EPS $-1.09. Year 2023: Revenue $331.4M, Net Income -$184.1M, EPS $-1.03. Year 2024: Revenue $450.7M, Net Income -$247.1M, EPS $-1.33. Year 2025: Revenue $874.8M, Net Income -$226.5M, EPS $-1.18.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Biocryst Pharmaceuticals Inc.'s revenue has grown significantly by 457% over the 5-year period, indicating strong business expansion. The most recent EPS of $-1.18 indicates the company is currently unprofitable.

BCRX Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
39.4%
Free cash flow / Revenue

BCRX Quarterly Earnings & Performance

Quarterly financial performance data for Biocryst Pharmaceuticals Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 $117.1M $32.0K $0.06
Q2 2025 $109.3M $32.0K $0.02
Q1 2025 $92.8M $32.0K $0.00
Q3 2024 $86.7M -$12.7M $-0.07
Q2 2024 $82.5M -$12.7M $-0.06
Q1 2024 $68.8M -$35.4M $-0.17
Q3 2023 $75.8M -$36.1M $-0.19
Q2 2023 $65.5M -$53.3M $-0.32

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Biocryst Pharmaceuticals Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
$347.4M
Cash generated from operations
Stock Buybacks
$61.0K
Shares repurchased (TTM)
Capital Expenditures
$2.5M
Investment in assets
Dividends
None
No dividend program

BCRX SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Biocryst Pharmaceuticals Inc. (CIK: 0000882796)

📋 Recent SEC Filings

Date Form Document Action
Apr 7, 2026 4 xslF345X06/form4.xml View →
Mar 24, 2026 4 xslF345X06/form4.xml View →
Mar 18, 2026 4 xslF345X06/form4.xml View →
Mar 3, 2026 4 xslF345X05/form4.xml View →
Mar 3, 2026 4 xslF345X05/form4.xml View →

Frequently Asked Questions about BCRX

What is the AI rating for BCRX?

Biocryst Pharmaceuticals Inc. (BCRX) has a Combined AI Rating of BUY from Claude (HOLD) and ChatGPT (BUY) with 72% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are BCRX's key strengths?

Claude: Exceptional revenue growth of 94.1% year-over-year indicating strong market demand. Impressive net income growth of 396.9% with net margin of 30.2% showing operational leverage. ChatGPT: Revenue growth is exceptionally strong at 94.1% YoY, indicating major commercial momentum. Profitability has improved meaningfully, with 39.0% operating margin and 30.2% net margin.

What are the risks of investing in BCRX?

Claude: Critical balance sheet weakness with negative stockholders' equity of -$119.2M indicating liabilities exceed assets by $119.2M. Total liabilities of $633.3M exceed total assets of $514.2M, creating solvency concerns. ChatGPT: Stockholders equity is negative, which signals accumulated balance sheet strain despite current profitability. Total liabilities exceed total assets, limiting financial flexibility if operating performance weakens.

What is BCRX's revenue and growth?

Biocryst Pharmaceuticals Inc. reported revenue of $874.8M.

Does BCRX pay dividends?

Biocryst Pharmaceuticals Inc. does not currently pay dividends.

Where can I find BCRX SEC filings?

Official SEC filings for Biocryst Pharmaceuticals Inc. (CIK: 0000882796) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is BCRX's EPS?

Biocryst Pharmaceuticals Inc. has a diluted EPS of $1.21.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is BCRX a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Biocryst Pharmaceuticals Inc. has a BUY rating with 72% confidence. The AI analysis suggests favorable fundamentals based on SEC filings. This is not investment advice.

Is BCRX stock overvalued or undervalued?

Valuation metrics for BCRX: ROE of N/A (sector avg: 15%), net margin of 30.2% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy BCRX stock in 2026?

Our dual AI analysis gives Biocryst Pharmaceuticals Inc. a combined BUY rating for 2026. Revenue is data pending, with profitability above sector average. Always conduct your own research.

What is BCRX's free cash flow?

Biocryst Pharmaceuticals Inc.'s operating cash flow is $347.4M, with capital expenditures of $2.5M. FCF margin is 39.4%.

How does BCRX compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin 30.2% (avg: 12%), ROE N/A (avg: 15%), current ratio 2.06 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Mar 20, 2026 | Data as of: 2025-12-31 | Powered by Claude AI